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Q1GTU1 (G6PI_SPHAL) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:Sala_1215
OrganismSphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) (Sphingomonas alaskensis) [Complete proteome] [HAMAP]
Taxonomic identifier317655 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeSphingopyxis

Protein attributes

Sequence length501 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 501501Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000252647

Sites

Active site3331Proton donor By similarity
Active site3641 By similarity
Active site4741 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1GTU1 [UniParc].

Last modified June 27, 2006. Version 1.
Checksum: 26281EBD752465AB

FASTA50153,610
        10         20         30         40         50         60 
MTIASDAWQA LADWQPQKLT DLVAADPDAR LQALVRNVAD IRFDFAKTHL DAAAIAILAN 

        70         80         90        100        110        120 
LAEAQDFGGR RKTLFSGGIA NPTENRAAEH SAERGDGAPE SVHAAQALHQ RMRMMIDAIE 

       130        140        150        160        170        180 
AGAFGEIRHL LHIGIGGSAL GPDLLVDALG RHSDRYDVAV VSNVDGAALD EAFAKFSPEH 

       190        200        210        220        230        240 
TLVAVASKTF TTTETLLNAN SALQWLDEAG VADPVGRFIA LTANPGRAME WGIDETRILP 

       250        260        270        280        290        300 
FSETVGGRYS LWSSIGFPAA LALGWDAFAD LLEGAAEMDR HFRLADGADN ICLLAAFADQ 

       310        320        330        340        350        360 
VYANRLGCQT RAVFAYDERL RLLPAYLQQL EMESNGKSVT LDGAPLAQHS APVTWGGVGT 

       370        380        390        400        410        420 
DAQHAVFQLL HQGTHLVPVE FIVAREPDHL LDDAHHETLV ANCIAQGAAL MAGRASDDRA 

       430        440        450        460        470        480 
RAYPGDRPST TILLDQVSPR SLGALIAFYE HRVFANAVLL GVNPFDQFGV ELGKEMAKGL 

       490        500 
AEGTVDFDPA TQALMKAALG D 

« Hide

References

[1]"Complete sequence of chromosome of Sphingopyxis alaskensis RB2256."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Munk A.C., Chertkov O., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Cavicchioli R., Robb F., Ertan H., Schut F., Ting L.M., Richardson P.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13593 / LMG 18877 / RB2256.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000356 Genomic DNA. Translation: ABF52931.1.
RefSeqYP_616264.1. NC_008048.1.

3D structure databases

ProteinModelPortalQ1GTU1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING317655.Sala_1215.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABF52931; ABF52931; Sala_1215.
GeneID4080439.
KEGGsal:Sala_1215.
PATRIC23691623. VBISphAla23391_1251.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMARAHYVSN.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycSALA317655:GHHY-1222-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_SPHAL
AccessionPrimary (citable) accession number: Q1GTU1
Entry history
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: June 27, 2006
Last modified: June 11, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways