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Q1GS60 (Q1GS60_SPHAL) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase HAMAP MF_00110

EC=4.2.3.4 HAMAP MF_00110
Gene names
Name:aroB HAMAP MF_00110
Ordered Locus Names:Sala_1800
OrganismSphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) (Sphingomonas alaskensis) [Complete proteome] [HAMAP]
Taxonomic identifier317655 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeSphingopyxis

Protein attributes

Sequence length368 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family. HAMAP MF_00110

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis HAMAP MF_00110
   Cellular componentCytoplasm HAMAP MF_00110
   LigandNAD HAMAP MF_00110
   Molecular functionLyase HAMAP MF_00110 EMBL ABF53512.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q1GS60 [UniParc].

Last modified June 27, 2006. Version 1.
Checksum: C632FC7420D37D7F

FASTA36838,385
        10         20         30         40         50         60 
MEKLTVELGA RSYPILIGDG LIRDIGAHVA PLLKRPRTMI VTDSHVADHY LAPIGTALAM 

        70         80         90        100        110        120 
ENIACSSFVL DPGEATKSWS GLARLTEWLI GEGIERSDHV IALGGGVIGD LVGFACSIVK 

       130        140        150        160        170        180 
RGCAFIQVPT TLLAQVDSSV GGKTAINVPA GKNLIGAFHQ PAMVVIDPTT LETLPRRELG 

       190        200        210        220        230        240 
AGYAEVVKYG LIDDADFFAW CEAHGAALLA GDSAARAHAI AHSVAAKARI VAADERETQD 

       250        260        270        280        290        300 
IRALLNLGHS FGHALEAETG YSDRLLHGEA VAAGMVLAHQ FSAANGLCPA ADAARVRDHL 

       310        320        330        340        350        360 
ASVGLPHSLA SAGINGGGAQ LAAHMAHDKK VRGGRLPLIL SRGIGQSFVT DAYDLDAVAA 


FLDEQRSV 

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References

[1]"Complete sequence of chromosome of Sphingopyxis alaskensis RB2256."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Munk A.C., Chertkov O., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Cavicchioli R., Robb F., Ertan H., Schut F., Ting L.M., Richardson P.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13593 / LMG 18877 / RB2256.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000356 Genomic DNA. Translation: ABF53512.1.
RefSeqYP_616845.1. NC_008048.1.

3D structure databases

ProteinModelPortalQ1GS60.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4082191.
GenomeReviewsGene locus Sala_1800 in contig CP000356_GR.
KEGGsal:Sala_1800.
NMPDRfig|317655.9.peg.1729.
PATRIC23692888. VBISphAla23391_1866.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG632303.
OMAMADEHEQ.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycSALA317655:SALA_1800-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ1GS60_SPHAL
AccessionPrimary (citable) accession number: Q1GS60
Entry history
Integrated into UniProtKB/TrEMBL: June 27, 2006
Last sequence update: June 27, 2006
Last modified: December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)