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Q1GS49 (Q1GS49_SPHAL) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A synthetase HAMAP MF_01123
EC=6.2.1.1 HAMAP MF_01123
Alternative name(s):
Acetate--CoA ligase HAMAP MF_01123
Acyl-activating enzyme HAMAP MF_01123
Gene names
Name:acsA HAMAP MF_01123
Ordered Locus Names:Sala_1811
OrganismSphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) (Sphingomonas alaskensis) [Complete proteome] [HAMAP]
Taxonomic identifier317655 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Sphingopyxis

Protein attributes

Sequence length654 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. HAMAP MF_01123

Post-translational modification

Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme By similarity. HAMAP MF_01123

Sequence similarities

Belongs to the ATP-dependent AMP-binding enzyme family. HAMAP MF_01123

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site5231 By similarity HAMAP MF_01123

Amino acid modifications

Modified residue6151N6-acetyllysine By similarity HAMAP MF_01123

Sequences

Sequence LengthMass (Da)Tools
Q1GS49 [UniParc].

Last modified June 27, 2006. Version 1.
Checksum: 5678958F482A7436

FASTA65471,409
        10         20         30         40         50         60 
MSDLPPSEPM VPVPADAAAN THCSAADYDR LYAASIADPD AFWAEQAKRL DWIKAPTRIA 

        70         80         90        100        110        120 
GWSYDPVSIK WYEDGVLNLC HNAVDRHVAA DHGDRTAIIF EPDAPDGETR HISYAALLAD 

       130        140        150        160        170        180 
VVRFANTLKK MGVRKGDRVT IYMPMIPEGA VAMLACARIG AVHSVVFGGF SPEAIHGRIE 

       190        200        210        220        230        240 
DCGSDWVICA DEGLRGGKTV PLKANVDKAL ERIAVRGVLV IAHTGGEVNM TEGRDHWYDA 

       250        260        270        280        290        300 
LSADVSADCP CEPMGAEDPL FILYTSGSTG KPKGVLHTVG GYSVWTATTF WYGFDYRPGE 

       310        320        330        340        350        360 
IFWCSADIGW VTGHSYVVYG PLQNGATTLM FEGVPNYPDH DRFWQVVDKH GVNILYTAPT 

       370        380        390        400        410        420 
AIRALMREGD DYVTRHDLSS LRLLGSVGEP INPEAWRWYH QIVGKGRVPV IDTWWQTETG 

       430        440        450        460        470        480 
GIMITTLPGA HPMQPGSAGR PFFGIRPQLV DADGAVLVDE QTGGAAEGNL CITHSWPGQA 

       490        500        510        520        530        540 
RTVYGDHDRF VQTYFSTYKG KYFTGDGCRR DASGYWRITG RVDDVINVSG HRMGTAEVES 

       550        560        570        580        590        600 
ALVLHEDVAE AAVVGFPHDI KGQGIYAYVT LNAGVEPGED IVAALKQQVR KEIGPIATPD 

       610        620        630        640        650 
HIHLTPALPK TRSGKIMRRI LRKIAENDFG SLGDTSTLAD PGLVDGLIEE RRNR

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References

[1]"Complete sequence of chromosome of Sphingopyxis alaskensis RB2256."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Munk A.C., Chertkov O., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Cavicchioli R., Robb F., Ertan H., Schut F., Ting L.M., Richardson P.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13593 / LMG 18877 / RB2256.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000356 Genomic DNA. Translation: ABF53523.1.
RefSeqYP_616856.1. NC_008048.1.

3D structure databases

ProteinModelPortalQ1GS49.
SMRQ1GS49. Positions 13-652.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4082202.
GenomeReviewsGene locus Sala_1811 in contig CP000356_GR.
KEGGsal:Sala_1811.
NMPDRfig|317655.9.peg.1740.
PATRIC23692912. VBISphAla23391_1878.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG547964.
OMAIARTIWG.
ProtClustDBCLSK753521.

Enzyme and pathway databases

BioCycSALA317655:SALA_1811-MONOMER.

Family and domain databases

HAMAPMF_01123. Ac_CoA_synth.
[Tree]
InterProIPR011904. Ac_CoA_lig.
IPR024597. Acyl-CoA_synth_DUF3448.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
KOK01895.
PANTHERPTHR24095:SF42. PTHR24095:SF42. 1 hit.
PfamPF00501. AMP-binding. 1 hit.
PF11930. DUF3448. 1 hit.
[Graphical view]
TIGRFAMsTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ1GS49_SPHAL
AccessionPrimary (citable) accession number: Q1GS49
Entry history
Integrated into UniProtKB/TrEMBL: June 27, 2006
Last sequence update: June 27, 2006
Last modified: December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info