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Q1GRU9 (Q1GRU9_SPHAL) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
GTP cyclohydrolase 1 HAMAP MF_00223
EC=3.5.4.16 HAMAP MF_00223
Alternative name(s):
GTP cyclohydrolase I HAMAP MF_00223
Gene names
Name:folE HAMAP MF_00223
Ordered Locus Names:Sala_1911
OrganismSphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) (Sphingomonas alaskensis) [Complete proteome] [HAMAP]
Taxonomic identifier317655 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Sphingopyxis

Protein attributes

Sequence length200 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. HAMAP MF_00223 SAAS SAAS001474

Pathway

Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. HAMAP MF_00223 SAAS SAAS001474

Subunit structure

Homopolymer By similarity. HAMAP MF_00223

Sequence similarities

Belongs to the GTP cyclohydrolase I family. HAMAP MF_00223

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding911Zinc By similarity HAMAP MF_00223
Metal binding941Zinc By similarity HAMAP MF_00223
Metal binding1621Zinc By similarity HAMAP MF_00223

Sequences

Sequence LengthMass (Da)Tools
Q1GRU9 [UniParc].

Last modified June 27, 2006. Version 1.
Checksum: AC169DBF17E2C8EF

FASTA20022,117
        10         20         30         40         50         60 
MSELGQDLGP DGKLIVPDHV ADAVRTLIEW AGDDPAREGL LDTPRRVARA WKEYCSGYGE 

        70         80         90        100        110        120 
DPSIHLSRTF EEVGGYDEVV LLRDIPFQSH CEHHMAPITG KASIAYLPRD RVVGISKLAR 

       130        140        150        160        170        180 
VLNGYARRLQ VQERLTAEVA QCIWDNLQPH GVAVVIDAQH GCMTGRGVRT PGVGMVTSRL 

       190        200 
LGCFLEDQRS RKEVLGLMGY

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References

[1]"Complete sequence of chromosome of Sphingopyxis alaskensis RB2256."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Munk A.C., Chertkov O., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Cavicchioli R., Robb F., Ertan H., Schut F., Ting L.M., Richardson P.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13593 / LMG 18877 / RB2256.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000356 Genomic DNA. Translation: ABF53623.1.
RefSeqYP_616956.1. NC_008048.1.

3D structure databases

ProteinModelPortalQ1GRU9.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4082767.
GenomeReviewsGene locus Sala_1911 in contig CP000356_GR.
KEGGsal:Sala_1911.
NMPDRfig|317655.9.peg.1839.
PATRIC23693116. VBISphAla23391_1979.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG370191.
OMAEPREYLE.
ProtClustDBCLSK944465.

Enzyme and pathway databases

BioCycSALA317655:SALA_1911-MONOMER.

Family and domain databases

HAMAPMF_00223. FolE.
[Tree]
InterProIPR001474. GTP_CycHdrlase_I.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
IPR018234. GTP_CycHdrlase_I_CS.
[Graphical view]
KOK01495.
PANTHERPTHR11109. GTP_cyclohydro_I. 1 hit.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsTIGR00063. FolE. 1 hit.
PROSITEPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
PS00860. GTP_CYCLOHYDROL_1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ1GRU9_SPHAL
AccessionPrimary (citable) accession number: Q1GRU9
Entry history
Integrated into UniProtKB/TrEMBL: June 27, 2006
Last sequence update: June 27, 2006
Last modified: December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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