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Protein

Putative thymidine phosphorylase

Gene

Sala_2473

Organism
Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) (Sphingomonas alaskensis)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciSALA317655:GHHY-2496-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylaseUniRule annotation (EC:2.4.2.4UniRule annotation)
Alternative name(s):
TdRPaseUniRule annotation
Gene namesi
Ordered Locus Names:Sala_2473
OrganismiSphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) (Sphingomonas alaskensis)
Taxonomic identifieri317655 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeSphingopyxis
Proteomesi
  • UP000006578 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003147181 – 514Putative thymidine phosphorylaseAdd BLAST514

Interactioni

Protein-protein interaction databases

STRINGi317655.Sala_2473

Structurei

3D structure databases

SMRiQ1GQ92
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CMW Bacteria
COG0213 LUCA
HOGENOMiHOG000252767
KOiK00758
OMAiVHSIGGV
OrthoDBiPOG091H02BC

Family and domain databases

Gene3Di3.40.1030.10, 2 hits
3.90.1170.30, 1 hit
HAMAPiMF_00703 Thymid_phosp_2, 1 hit
InterProiView protein in InterPro
IPR000312 Glycosyl_Trfase_fam3
IPR017459 Glycosyl_Trfase_fam3_N_dom
IPR036320 Glycosyl_Trfase_fam3_N_dom)sf
IPR035902 Nuc_phospho_transferase
IPR036566 PYNP-like_C_sf
IPR013102 PYNP_C
IPR017872 Pyrmidine_PPase_CS
IPR028579 Thym_Pase_Put
IPR013466 Thymidine/AMP_Pase
IPR000053 Thymidine/pyrmidine_PPase
PANTHERiPTHR10515 PTHR10515, 1 hit
PfamiView protein in Pfam
PF02885 Glycos_trans_3N, 1 hit
PF00591 Glycos_transf_3, 1 hit
PF07831 PYNP_C, 1 hit
PIRSFiPIRSF000478 TP_PyNP, 1 hit
SMARTiView protein in SMART
SM00941 PYNP_C, 1 hit
SUPFAMiSSF47648 SSF47648, 1 hit
SSF52418 SSF52418, 1 hit
SSF54680 SSF54680, 1 hit
TIGRFAMsiTIGR02645 ARCH_P_rylase, 1 hit
PROSITEiView protein in PROSITE
PS00647 THYMID_PHOSPHORYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q1GQ92-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHPVPDTGP ASENMAPHRL RARPLGLFLP QQQPAVVMRT DCYICRSEGL
60 70 80 90 100
AARSQVLIQA GGREILASLL HSSGEMIAPG EIGLSESAAA ALGVAPGDAV
110 120 130 140 150
SVRHAPPIDS FGALRGRVYG NRLDGAAFRS IVDDIVAGRY SDVHLSAFVT
160 170 180 190 200
ACSAFPLDHA ETVALTGAMV ASGERLAWGS DVVVDKHSVG GLPGNRTTPI
210 220 230 240 250
VVAIVAALGL IMPKTSSRAI TSPAGTADTM ETLAPVNLDV GAIRRVVDHE
260 270 280 290 300
GGCIVWGGAV SLSPADDIII GVERVLDLDA AGQLVASVLS KKLAAGATHL
310 320 330 340 350
VVDMPIGPTA KVRSPADAAA LSGALQKVAA EFGLILKVMQ GDGREPIGRG
360 370 380 390 400
IGPALEARDI LAVLEGRDPP PDLARRACEL AGALIELAGR ASPGTGAALA
410 420 430 440 450
AQVLADGSAW SKFQRICEAQ GGMRTPPLSN HRHVMTAQRP GRVSAIDNRR
460 470 480 490 500
LAKLAKLAGA PAAKSAGLEM HVRLGSAVET GTPLLTVHAE SQGELAYALA
510
YAEAVGPILE LSDR
Length:514
Mass (Da):52,830
Last modified:June 27, 2006 - v1
Checksum:i7FB57264EA8DACDA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000356 Genomic DNA Translation: ABF54180.1
RefSeqiWP_011542745.1, NC_008048.1

Genome annotation databases

EnsemblBacteriaiABF54180; ABF54180; Sala_2473
KEGGisal:Sala_2473

Similar proteinsi

Entry informationi

Entry nameiTYPH_SPHAL
AccessioniPrimary (citable) accession number: Q1GQ92
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 27, 2006
Last modified: March 28, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health