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Q1GQ92

- TYPH_SPHAL

UniProt

Q1GQ92 - TYPH_SPHAL

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Protein

Putative thymidine phosphorylase

Gene

Sala_2473

Organism
Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) (Sphingomonas alaskensis)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

  1. phosphorylase activity Source: InterPro
  2. thymidine phosphorylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pyrimidine nucleobase metabolic process Source: InterPro
  2. pyrimidine nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciSALA317655:GHHY-2507-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylaseUniRule annotation (EC:2.4.2.4UniRule annotation)
Alternative name(s):
TdRPaseUniRule annotation
Gene namesi
Ordered Locus Names:Sala_2473
OrganismiSphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) (Sphingomonas alaskensis)
Taxonomic identifieri317655 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeSphingopyxis
ProteomesiUP000006578: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 514514Putative thymidine phosphorylasePRO_0000314718Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi317655.Sala_2473.

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0213.
HOGENOMiHOG000252767.
KOiK00758.
OMAiIHYNDEA.
OrthoDBiEOG61ZTGG.

Family and domain databases

Gene3Di3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPiMF_00703. Thymid_phosp_2.
InterProiIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERiPTHR10515. PTHR10515. 1 hit.
PfamiPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000478. TP_PyNP. 1 hit.
SMARTiSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMiSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsiTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEiPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1GQ92-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTHPVPDTGP ASENMAPHRL RARPLGLFLP QQQPAVVMRT DCYICRSEGL
60 70 80 90 100
AARSQVLIQA GGREILASLL HSSGEMIAPG EIGLSESAAA ALGVAPGDAV
110 120 130 140 150
SVRHAPPIDS FGALRGRVYG NRLDGAAFRS IVDDIVAGRY SDVHLSAFVT
160 170 180 190 200
ACSAFPLDHA ETVALTGAMV ASGERLAWGS DVVVDKHSVG GLPGNRTTPI
210 220 230 240 250
VVAIVAALGL IMPKTSSRAI TSPAGTADTM ETLAPVNLDV GAIRRVVDHE
260 270 280 290 300
GGCIVWGGAV SLSPADDIII GVERVLDLDA AGQLVASVLS KKLAAGATHL
310 320 330 340 350
VVDMPIGPTA KVRSPADAAA LSGALQKVAA EFGLILKVMQ GDGREPIGRG
360 370 380 390 400
IGPALEARDI LAVLEGRDPP PDLARRACEL AGALIELAGR ASPGTGAALA
410 420 430 440 450
AQVLADGSAW SKFQRICEAQ GGMRTPPLSN HRHVMTAQRP GRVSAIDNRR
460 470 480 490 500
LAKLAKLAGA PAAKSAGLEM HVRLGSAVET GTPLLTVHAE SQGELAYALA
510
YAEAVGPILE LSDR
Length:514
Mass (Da):52,830
Last modified:June 27, 2006 - v1
Checksum:i7FB57264EA8DACDA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000356 Genomic DNA. Translation: ABF54180.1.
RefSeqiWP_011542745.1. NC_008048.1.
YP_617513.1. NC_008048.1.

Genome annotation databases

EnsemblBacteriaiABF54180; ABF54180; Sala_2473.
GeneIDi4081311.
KEGGisal:Sala_2473.
PATRICi23694298. VBISphAla23391_2563.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000356 Genomic DNA. Translation: ABF54180.1 .
RefSeqi WP_011542745.1. NC_008048.1.
YP_617513.1. NC_008048.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 317655.Sala_2473.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABF54180 ; ABF54180 ; Sala_2473 .
GeneIDi 4081311.
KEGGi sal:Sala_2473.
PATRICi 23694298. VBISphAla23391_2563.

Phylogenomic databases

eggNOGi COG0213.
HOGENOMi HOG000252767.
KOi K00758.
OMAi IHYNDEA.
OrthoDBi EOG61ZTGG.

Enzyme and pathway databases

BioCyci SALA317655:GHHY-2507-MONOMER.

Family and domain databases

Gene3Di 3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPi MF_00703. Thymid_phosp_2.
InterProi IPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view ]
PANTHERi PTHR10515. PTHR10515. 1 hit.
Pfami PF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF000478. TP_PyNP. 1 hit.
SMARTi SM00941. PYNP_C. 1 hit.
[Graphical view ]
SUPFAMi SSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsi TIGR02645. ARCH_P_rylase. 1 hit.
PROSITEi PS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13593 / LMG 18877 / RB2256.

Entry informationi

Entry nameiTYPH_SPHAL
AccessioniPrimary (citable) accession number: Q1GQ92
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 27, 2006
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3