Q1GPD7 (Q1GPD7_SPHAL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	Sala_2780

Organism

Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) (Sphingomonas alaskensis) [Complete proteome] [HAMAP]

Taxonomic identifier

317655 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Sphingopyxis

Protein attributes

Sequence length	1092 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1GPD7 [UniParc]. Last modified June 27, 2006. Version 1. Checksum: 458C50D7D8A02582	FASTA	1,092	122,905
	10 20 30 40 50 60 MSENRFGPGF AELVAATNYS FLRGASHPAE MVKEALDLGM SGIGIADRNS VAGVVRALTG 70 80 90 100 110 120 LRKLHEDAAE EGIELPPFQL VVGARLVFDD GTPDIVAYPT TRHGWGRLTR MLTIGNRRTT 130 140 150 160 170 180 KGGCVMKLKN LLIHCQDMIL IAMAGEKDEA VLRRLKKIAP NALWLGATMP REGSDRRHLA 190 200 210 220 230 240 RLQSLADRVG IPMLATNDAL YATREQRPLH DVVTCIREGT TLHEAGRLLR ANGERHLKSP 250 260 270 280 290 300 QEMRRLFRAC PSAVDESIRI LDRIGFSLRD LEYEYPHEPV PEGWDPQSWL EHMVLDAANR 310 320 330 340 350 360 LHPQGLPQRW QEVLDEELSL IRKCNFACYF LTVHDIVKYA RSQDPPILCQ GRGSAANSLV 370 380 390 400 410 420 CYLLEITSID PIANNLLFTR FLSEERREPP DIDVDFEHER REEVMQYIYR RHTRRRAGIA 430 440 450 460 470 480 ATVIHYRPRS AVREVGKALG LSEDVTARLA DTSWGSWGSE MPVERFVEAG LDPEQDDMAR 490 500 510 520 530 540 LQWIVAQLLT FPRHLSQHVG GYVLTEDRLD ETVPIHNAAM AERTFIEWDK DDLDELRLMK 550 560 570 580 590 600 VDVLALGMLT CIRKCFDLMR LHGLGDHDLK SVPPEDPVVY DMLCKGDSIG VFQVESRAQI 610 620 630 640 650 660 NMLPRLRPRK FYDLVIQVAI VRPGPIEGDM VHPYLRRRNK EEKPELPLRA GAEANELEAV 670 680 690 700 710 720 LGKTEGVPLF QEQAMKLAIV AAGFSPDEAN GLRRAMATFR NVGTIHQYRE KMIGGMVRRG 730 740 750 760 770 780 YEADFAARCF KQIEGFGSYG FPESHAQSFA KLVYVSSWLK CHHPAVFTCG LLNSQPMGFY 790 800 810 820 830 840 APAQLVRDAR EHGVEVREVD VNASHWDNGL ERRADGSLAL RLGFRQVDGF REAWADQIVA 850 860 870 880 890 900 ARTTSFASVE DLARRAKLPP RALRLLAEAD ACRSMGLDRR PALWEARRVR QGVLPLFGAA 910 920 930 940 950 960 GANELGHEED AALPPTPMVE HVLTDYQTTR LSLKGHPMAF LRRDFARAGV LSAVEVAAAK 970 980 990 1000 1010 1020 NGAIVRTAGV VLIRQRPGKG NAIFITIEDE SGIVNILLWA RHFERYRRAV MASRLMLAEG 1030 1040 1050 1060 1070 1080 EVQRSKEGVI HLMATRIADR TAMLDTLGAD RRFDPDLARA DEVKHPQYPR GHAQRHGHPR 1090 DVRILPKSRD FH

References

[1]

"Complete sequence of chromosome of Sphingopyxis alaskensis RB2256." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Munk A.C., Chertkov O., Gilna P. , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Cavicchioli R., Robb F., Ertan H., Schut F., Ting L.M., Richardson P. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13593 / LMG 18877 / RB2256.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000356 Genomic DNA. Translation: ABF54485.1.
RefSeq	YP_617818.1. NC_008048.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4080361.
GenomeReviews	Gene locus Sala_2780 in contig CP000356_GR.
KEGG	sal:Sala_2780.
NMPDR	fig|317655.9.peg.2645.
PATRIC	23694926. VBISphAla23391_2871.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG734490.
OMA	LATNRNG.
ProtClustDB	CLSK753846.
Enzyme and pathway databases
BioCyc	SALA317655:SALA_2780-MONOMER.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q1GPD7_SPHAL

Accession

Primary (citable) accession number: Q1GPD7

Entry history

Integrated into UniProtKB/TrEMBL:	June 27, 2006
Last sequence update:	June 27, 2006
Last modified:	December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)