Q1GNU5 (Q1GNU5_SPHAL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA gyrase subunit B RuleBase RU003363
EC=5.99.1.3 RuleBase RU003363

Gene names

Ordered Locus Names:

Sala_2972

Organism

Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) (Sphingomonas alaskensis) [Complete proteome] [HAMAP]

Taxonomic identifier

317655 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Sphingopyxis

Protein attributes

Sequence length	858 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. RuleBase RU003363
Catalytic activity	ATP-dependent breakage, passage and rejoining of double-stranded DNA. RuleBase RU003363 SAAS SAAS002288
Sequence similarities	Belongs to the type II topoisomerase family. RuleBase RU000380 Contains 1 Toprim domain. SAAS SAAS002288

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS002288 RuleBase RU000380 Nucleotide-binding
Molecular function	Isomerase Topoisomerase SAAS SAAS002288 RuleBase RU000380
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA topoisomerase (ATP-hydrolyzing) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1GNU5 [UniParc]. Last modified June 27, 2006. Version 1. Checksum: 2345F021A32E6067	FASTA	858	93,328
	10 20 30 40 50 60 MTDTPENSAP EGAAKQPNAN AYGADSIKVL KGLDAVRKRP GMYIGDTDDG SGLHHMVFEV 70 80 90 100 110 120 SDNAIDEALA GHCDLILITL NSDGSVSVED NGRGIPTDIH AEEGVSAAEV IMTQLHAGGK 130 140 150 160 170 180 FENTSDDNAY KVSGGLHGVG VSVVNALSEW LELTIWRDGQ EHWMRFEHGD AVAPLRVNGP 190 200 210 220 230 240 APAGKKGTRV TFQASTDTFK NVTEFDFEKL EHRYRELAFL NSGVRIKLVD ARHAEHVSHD 250 260 270 280 290 300 LFYEGGIAAF VKYLDRNKTP LLPDPIAISS ERDGIGIDVA LEWNDSYYEN VLCFTNNIPQ 310 320 330 340 350 360 RDGGTHLAAF RAALTRTLNG YGEKSGLLKK EKVSLTGEDM REGLTAIVSV KLPDPKFSSQ 370 380 390 400 410 420 TKDKLVSSEV RQPLESLMAD RMTEWLEENP AYAKAVIQKV VDAAAAREAA KKARELTRRK 430 440 450 460 470 480 GAMDIASLPG KLADCQERDP AKCELFLVEG DSAGGSAKQG RDRHVQAILP LKGKILNVER 490 500 510 520 530 540 ARFDRIISSK EVGTLIQALG TGIRDEFNIE KLRYHKIVIM TDADVDGAHI RTLLLTFFYR 550 560 570 580 590 600 QMPEIIEKGH LYIAQPPLYK VAKGRSEVYL KDDSALENYL VDGGIDALML ETTGGARSGA 610 620 630 640 650 660 DLRGLIEHGR RLRALMRYVP RGHNYGLVEA LALNGALDPA LDSAGRTAAA VRAAEWLNAA 670 680 690 700 710 720 ERALTGGAEA KWTITAAGGG YTLEKRWRGV SDHHAIDAAF LASQEARRLH TLAAEQAETY 730 740 750 760 770 780 AHPARLVKGS SAAALAADAA ALAATEAAED DAEASDGDLP AATARKVTPI TRPSELLEAI 790 800 810 820 830 840 FAHSRKGLAI SRYKGLGEMN AEQLWETTLD PSNRSLLRVE AEQADIAHEI FERLMGDEVE 850 PRRDFIQTNA LSVANLDV

References

[1]

"Complete sequence of chromosome of Sphingopyxis alaskensis RB2256." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Munk A.C., Chertkov O., Gilna P. , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Cavicchioli R., Robb F., Ertan H., Schut F., Ting L.M., Richardson P. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13593 / LMG 18877 / RB2256.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000356 Genomic DNA. Translation: ABF54677.1.
RefSeq	YP_618010.1. NC_008048.1.
3D structure databases
ProteinModelPortal	Q1GNU5.
SMR	Q1GNU5. Positions 27-402.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4081088.
GenomeReviews	Gene locus Sala_2972 in contig CP000356_GR.
KEGG	sal:Sala_2972.
NMPDR	fig|317655.9.peg.2829.
PATRIC	23695314. VBISphAla23391_3064.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304889.
OMA	DCSSRDP.
ProtClustDB	PRK14939.
Enzyme and pathway databases
BioCyc	SALA317655:SALA_2972-MONOMER.
Family and domain databases
HAMAP	MF_01898. GyrB. [Tree]
InterPro	IPR003594. ATPase-like_ATP-bd. IPR011557. GyrB. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR001241. Topo_IIA. IPR013759. Topo_IIA_B/N_ab. IPR002288. Topo_IIA_B_C. IPR013506. Topo_IIA_bsu_dom2. IPR013760. Topo_IIA_cen. IPR018522. TopoIIA_CS. IPR006171. Toprim_domain. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit. G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 2 hits.
KO	K02470.
Pfam	PF00204. DNA_gyraseB. 1 hit. PF00986. DNA_gyraseB_C. 1 hit. PF02518. HATPase_c. 1 hit. PF01751. Toprim. 1 hit. [Graphical view]
PRINTS	PR00418. TPI2FAMILY.
SMART	SM00387. HATPase_c. 1 hit. SM00433. TOP2c. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMs	TIGR01059. GyrB. 1 hit.
PROSITE	PS00177. TOPOISOMERASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q1GNU5_SPHAL

Accession

Primary (citable) accession number: Q1GNU5

Entry history

Integrated into UniProtKB/TrEMBL:	June 27, 2006
Last sequence update:	June 27, 2006
Last modified:	January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)