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Protein

Uronate isomerase

Gene

uxaC

Organism
Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) (Sphingomonas alaskensis)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. glucuronate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glucuronate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciSALA317655:GHHY-3089-MONOMER.
UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:Sala_3046
OrganismiSphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) (Sphingomonas alaskensis)
Taxonomic identifieri317655 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeSphingopyxis
ProteomesiUP000006578: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 470470Uronate isomerasePRO_1000044777Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi317655.Sala_3046.

Structurei

3D structure databases

ProteinModelPortaliQ1GNM2.
SMRiQ1GNM2. Positions 3-470.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1904.
HOGENOMiHOG000238114.
KOiK01812.
OMAiGHTDPRW.
OrthoDBiEOG6J1D95.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1GNM2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPRPLYLSPD RLFPSDPAQR DIARRLYKAV AGLPIVSPHG HTDPAWFAGD
60 70 80 90 100
APFGNAAELL LHPDHYVFRM LYSQGVSLDA LGIGNADADP RESWRLFAEN
110 120 130 140 150
YHLFRATPSR MWMDWVFAEV FGFDVQLSAE TSDLYYDRIT EALAIDAFRP
160 170 180 190 200
RALFDRFGIE VIATTESPLD SLDHHAVIRA ANASGEWGGR VITAYRPDPV
210 220 230 240 250
VDPEFEGFRD NLARFSNLSG EDAFSYSGYL AAHRKRRAFF ASMGATSTDH
260 270 280 290 300
GHPSAATADL SETQAEALFA RVTGEDMSAA DAELFRAHML TVMAGMSLDD
310 320 330 340 350
GLVMQIHPGA FRNHNPWLFA NHGRDKGADI PTATDYVHAL RPLLGRYGNE
360 370 380 390 400
ADLTIILFTL DETSYARELA PLAGHYPALK LGPAWWFHDS PEGMRRFRSQ
410 420 430 440 450
MTETAGFYNT VGFNDDTRAF LSIPARHDVA RRIDCGFLAQ LVSEHRLEEW
460 470
EAAELAADLS YNLAKASYKL
Length:470
Mass (Da):52,409
Last modified:June 27, 2006 - v1
Checksum:i93040A502BA83DDB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000356 Genomic DNA. Translation: ABF54750.1.
RefSeqiYP_618083.1. NC_008048.1.

Genome annotation databases

EnsemblBacteriaiABF54750; ABF54750; Sala_3046.
GeneIDi4083054.
KEGGisal:Sala_3046.
PATRICi23695470. VBISphAla23391_3140.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000356 Genomic DNA. Translation: ABF54750.1.
RefSeqiYP_618083.1. NC_008048.1.

3D structure databases

ProteinModelPortaliQ1GNM2.
SMRiQ1GNM2. Positions 3-470.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi317655.Sala_3046.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABF54750; ABF54750; Sala_3046.
GeneIDi4083054.
KEGGisal:Sala_3046.
PATRICi23695470. VBISphAla23391_3140.

Phylogenomic databases

eggNOGiCOG1904.
HOGENOMiHOG000238114.
KOiK01812.
OMAiGHTDPRW.
OrthoDBiEOG6J1D95.

Enzyme and pathway databases

UniPathwayiUPA00246.
BioCyciSALA317655:GHHY-3089-MONOMER.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC.
InterProiIPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13593 / LMG 18877 / RB2256.

Entry informationi

Entry nameiUXAC_SPHAL
AccessioniPrimary (citable) accession number: Q1GNM2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 27, 2006
Last modified: February 4, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.