ID   Q1GMD3_RUEST            Unreviewed;       782 AA.
AC   Q1GMD3;
DT   27-JUN-2006, integrated into UniProtKB/TrEMBL.
DT   27-JUN-2006, sequence version 1.
DT   27-MAR-2024, entry version 101.
DE   SubName: Full=Methyl-accepting chemotaxis sensory transducer {ECO:0000313|EMBL:ABF62183.1};
GN   Name=mcpB {ECO:0000313|EMBL:ABF62183.1};
GN   OrderedLocusNames=TM1040_3209 {ECO:0000313|EMBL:ABF62183.1};
OS   Ruegeria sp. (strain TM1040) (Silicibacter sp.).
OG   Plasmid megaplasmid TM1040 {ECO:0000313|Proteomes:UP000000636}.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Ruegeria.
OX   NCBI_TaxID=292414 {ECO:0000313|EMBL:ABF62183.1, ECO:0000313|Proteomes:UP000000636};
RN   [1] {ECO:0000313|Proteomes:UP000000636}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TM1040 {ECO:0000313|Proteomes:UP000000636};
RC   PLASMID=megaplasmid TM1040 {ECO:0000313|Proteomes:UP000000636};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Brettin T., Bruce D., Han C., Tapia R., Goodwin L., Thompson L.S.,
RA   Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA   Belas R., Moran M.A., Buchan A., Gonzalez J.M., Schell M.A., Sun F.,
RA   Richardson P.;
RT   "Complete sequence of megaplasmid of Silicibacter sp. TM1040.";
RL   Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABF62183.1, ECO:0000313|Proteomes:UP000000636}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TM1040 {ECO:0000313|EMBL:ABF62183.1,
RC   ECO:0000313|Proteomes:UP000000636};
RC   PLASMID=megaplasmid TM1040 {ECO:0000313|Proteomes:UP000000636};
RX   PubMed=17526795; DOI=10.1128/AEM.02580-06;
RA   Moran M.A., Belas R., Schell M.A., Gonzalez J.M., Sun F., Sun S.,
RA   Binder B.J., Edmonds J., Ye W., Orcutt B., Howard E.C., Meile C.,
RA   Palefsky W., Goesmann A., Ren Q., Paulsen I., Ulrich L.E., Thompson L.S.,
RA   Saunders E., Buchan A.;
RT   "Ecological genomics of marine Roseobacters.";
RL   Appl. Environ. Microbiol. 73:4559-4569(2007).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000376; ABF62183.1; -; Genomic_DNA.
DR   RefSeq; WP_011536827.1; NC_008043.1.
DR   AlphaFoldDB; Q1GMD3; -.
DR   KEGG; sit:TM1040_3209; -.
DR   HOGENOM; CLU_000445_107_12_5; -.
DR   OrthoDB; 354287at2; -.
DR   Proteomes; UP000000636; Plasmid megaplasmid TM1040.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR43531:SF11; METHYL-ACCEPTING CHEMOTAXIS PROTEIN 3; 1.
DR   PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 2.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 2.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Plasmid {ECO:0000313|EMBL:ABF62183.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000636};
KW   Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          366..419
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          429..481
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          486..715
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          490..509
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          728..782
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        739..755
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   782 AA;  84440 MW;  FAAEF38C7AE7F1DA CRC64;
     MIALSQLKIR YKLPAFLVGF ALLASAILVT VSTVNYQRNA WITVENRFES IAADRASVLE
     ALFQTMRADV EVLAELPSTA TAAQRISAAW SGVSDSPAET LRQMYISENP HPPHERFMME
     RAQKTIPYNI HHANFHPSFR SLLISKGYSD AYLVNIAGDV IYSVAKQDDY GSNLLSGPHQ
     TSNLAATFKR IMTAAPEEVL FSDFEHFAPR DDTPMAFVGT QIVASSGQLV GVFILQIPDT
     LVSEIISPAE GLGVSTEVFV VGTDGKARSQ SRFDDGHNVL EDLAFSLQER AATEPQIFDS
     NATGIRGKPV VAMARQLPIE EKVWILAVEQ DRDEVLAPVR GDRMLLILTS LASALVMTGI
     GWWFARSFLK PIDGLCARMS EISEGQLDAP IPEADRADEF GHMGQILRTM QGDLQRAKDA
     DAHRQHLQEQ QAEVVRHISE GLVQVANGNL AHRITEPFDA DYEKLRSDFN SALTELSDVV
     SQVTETADGI RSGADEISQA SDDLSSRTES QAATLEETVA ALDELTASVK SAAEGARNVE
     DIVKQARGEA EKSDEVVRNA VDAMTKIETS SAKISQIISV IDDISFQTNL LALNAGVEAA
     RAGEAGRGFA VVASEVRGLA QRSSQAALEI KNLISESTQQ VGEGVELVDA AGDSLRSIAE
     RVSHISSLVS EIAQGATDQS AGLSEINDGM TQLDQVTQKN AAMVEESTAA SHLLKSDANK
     LAELVSHFET GQASAPKRAQ PADDRRPETP RASAHGEDIA FDPPPPIATS TGSAARDLWQ
     DF
//