Q1GKA8 (Q1GKA8_SILST) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	TM1040_0175

Organism

Silicibacter sp. (strain TM1040) [Complete proteome] [HAMAP]

Taxonomic identifier

292414 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Ruegeria

Protein attributes

Sequence length	1126 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1GKA8 [UniParc]. Last modified June 27, 2006. Version 1. Checksum: 4F68B33C3C2B064A	FASTA	1,126	125,209
	10 20 30 40 50 60 MEPNRTHRPV ETFSTARLSP PHAGPGYAEL CVTSNFTFLT GASHPEELVT RAAELGLAAI 70 80 90 100 110 120 AITDRNSLAG VVRAWSALKE LRREAEAGIQ IRSHQRVDPS SRQKIDTSAP LEPPAAPTLP 130 140 150 160 170 180 KLIVGCRLVL RDSQTDWIAL PRDRAAYARL TRLLTLGKRR APKGECHLDA RDLMAACRGM 190 200 210 220 230 240 SLIALPQSDL KTAIPEIRRM QQCFPHYVFL GAAPRYDGSD QAYLAACAHA AQITSAPMVA 250 260 270 280 290 300 VGDVLMHRAS RRPLADVLTC MREHITIDEI GSRALPNSER RLKAGADMAR LFQAHPAALR 310 320 330 340 350 360 RTLEIADKCS FDLGELSYDY PHEIVDGETP QARLERLAAE GLRRRYPDGP TQKAVVLMDK 370 380 390 400 410 420 ELKLVAELGF AAYFLTVHDI VQYAKSQNIL CQGRGSAANS ILCYLLGITD VSPDMITMVF 430 440 450 460 470 480 ERFVSRYRGE PPDIDVDFEH ERREEVIQWI YQKYGRDRAG LCATVIHFRS RAAIREVGKV 490 500 510 520 530 540 MGLSQDVTAG LSGQIWGMSN GGVDLKRIEE LGLDIQDRRL MQTIRLIGEI IGFPRHLSQH 550 560 570 580 590 600 VGGFVITKGR LDELAPIENA AMEDRTVIEW DKDDIDALGI LKVDVLSLGM LTCLQKSFAL 610 620 630 640 650 660 LKAHEGETLS IGTVPQEDAK TYAMLCRADA VGVFQVESRA QMNFLPRMQP REFYDLVIEV 670 680 690 700 710 720 AIVRPGPIQG DMVQPYIRRR NGLEEPEPFG PELEQVTKRT LGVPLFQEQA MQIAVVGAGF 730 740 750 760 770 780 TPEEADHLRR SLASFRRMGT IGTFRDKFIN GMLDKGYSQE VAARCFSQIE GFADYGFPES 790 800 810 820 830 840 HAAAFAMLAY VSAWLKCHHP AVFACALLNS QPMGFYAPAQ IVRDAREHGV EIRPICVNAS 850 860 870 880 890 900 DWDNQLERRP DGALALRLGF RQIKGFREED AGWITAARGN GYPDPESLWL RAGLRPDVLT 910 920 930 940 950 960 RLAEADAFSD MGLTRRDALW QVKAIRSAKP LPLFDDPIDG ESISEPAVDL PVMHLGEEVV 970 980 990 1000 1010 1020 EDYISTRLTL RAHPMELLRP ALPGLTPHAA LLDAPLGRHT VCGLVITRQR PGTASGVIFL 1030 1040 1050 1060 1070 1080 TLEDETGVSN VVVWPKIYEQ YRRIVMGGRL LQVRGYLQRE GIVVHLIAQE ITDMSHRLSD 1090 1100 1110 1120 LGHPLDEAVG ITQPQADDAP RPRQATTSAR HPREQAKRLF PSRDFH

References

[1]

"Complete sequence of chromosome of Silicibacter sp. TM1040." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Goodwin L., Thompson L.S., Gilna P. , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Belas R., Moran M.A., Buchan A., Gonzalez J.M., Schell M.A., Sun F., Richardson P. Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TM1040.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000377 Genomic DNA. Translation: ABF62908.1.
RefSeq	YP_612170.1. NC_008044.1.
3D structure databases
ProteinModelPortal	Q1GKA8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1GKA8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4078783.
GenomeReviews	Gene locus TM1040_0175 in contig CP000377_GR.
KEGG	sit:TM1040_0175.
NMPDR	fig|292414.1.peg.2628.
PATRIC	23384403. VBIRueSp69653_1037.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	ADYCANG.
ProtClustDB	CLSK933325.
Enzyme and pathway databases
BioCyc	SSP292414:TM1040_0175-MONOMER.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q1GKA8_SILST

Accession

Primary (citable) accession number: Q1GKA8

Entry history

Integrated into UniProtKB/TrEMBL:	June 27, 2006
Last sequence update:	June 27, 2006
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)