Q1GK79 (TRPF_RUEST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	TM1040_0204

Organism

Ruegeria sp. (strain TM1040) (Silicibacter sp.) [Complete proteome] [HAMAP]

Taxonomic identifier

292414 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Ruegeria

Protein attributes

Sequence length	215 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 215	215	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135		PRO_1000018639

Sequences

	Sequence		Length	Mass (Da)
	Q1GK79 [UniParc]. Last modified June 27, 2006. Version 1. Checksum: 01B1D9DEADEE6921	FASTA	215	22,433
	10 20 30 40 50 60 MADIRVKICG MKTRADMEAA AAAGAAYVGL NFYAKSARSV TIAQAAALAS DAPVGLAKVG 70 80 90 100 110 120 LVVNPTDADL DAITGSVPLD MIQLHGQESV ERVAEIKTRY GLPVMKVIGV AEAADLDPID 130 140 150 160 170 180 LYAQVADQLM VDAKAPKGAK LPGGNGISFD WQLLASKKYW QAPWMLAGGL TPENVAEAIR 190 200 210 KTGARQVDVA SGVESAPAQK DPDLMRAFVE AAQAV

References

[1]

"Complete sequence of chromosome of Silicibacter sp. TM1040." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Goodwin L., Thompson L.S., Gilna P. , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Belas R., Moran M.A., Buchan A., Gonzalez J.M., Schell M.A., Sun F., Richardson P. Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TM1040.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000377 Genomic DNA. Translation: ABF62937.1.
RefSeq	YP_612199.1. NC_008044.1.
3D structure databases
ProteinModelPortal	Q1GK79.
ModBase	Search...
Protein-protein interaction databases
STRING	292414.TM1040_0204.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABF62937; ABF62937; TM1040_0204.
GeneID	4078652.
KEGG	sit:TM1040_0204.
PATRIC	23384461. VBIRueSp69653_1066.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0135.
HOGENOM	HOG000161598.
KO	K01817.
OMA	PVIRAIQ.
ProtClustDB	PRK01222.
Enzyme and pathway databases
BioCyc	RSP292414:GHCT-255-MONOMER.
UniPathway	UPA00035; UER00042.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00135. PRAI.
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_RUEST

Accession

Primary (citable) accession number: Q1GK79

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	June 27, 2006
Last modified:	May 1, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program