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Q1GGQ1 (AROB_SILST) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:TM1040_1432
OrganismSilicibacter sp. (strain TM1040) [Complete proteome] [HAMAP]
Taxonomic identifier292414 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Ruegeria

Protein attributes

Sequence length373 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3733733-dehydroquinate synthase HAMAP MF_00110
PRO_1000094623

Sequences

Sequence LengthMass (Da)Tools
Q1GGQ1 [UniParc].

Last modified June 27, 2006. Version 1.
Checksum: 4B860377F2FE5930

FASTA37339,431
        10         20         30         40         50         60 
MEQTVHVPLG ARAYDVVIGP DLVAQAGQRI APLLRRKTVA VLTDETVAAL HLEALRAGLA 

        70         80         90        100        110        120 
ADGIEMEALA LPPGEATKGW PQFTRAVEWL LDKKVERGDI VIAFGGGVIG DLAGFAAAVL 

       130        140        150        160        170        180 
RRGVRFVQIP TSLLAQVDSS VGGKTGINAP QGKNLIGAFH QPSLVLADTA VLGTLTERDF 

       190        200        210        220        230        240 
LAGYGEVVKY GLLGDAAFFD WLEENAPAMA AGDMALRVEA VARSVQMKAD IVARDETEQG 

       250        260        270        280        290        300 
DRALLNLGHT FCHALEAATG YSDRLLHGEG VAIGCALAFE LSARLGLCSQ EDPSRVRAHL 

       310        320        330        340        350        360 
KAMGMKTDLS DIPGDLPPAQ ELLDLMAQDK KVVDGQLRFI LARGIGAAFV TADVPSEKVL 

       370 
EVLQEALAHT QPA

« Hide

References

[1]"Complete sequence of chromosome of Silicibacter sp. TM1040."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Goodwin L., Thompson L.S., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Belas R., Moran M.A., Buchan A., Gonzalez J.M., Schell M.A., Sun F., Richardson P.
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TM1040.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000377 Genomic DNA. Translation: ABF64165.1.
RefSeqYP_613427.1. NC_008044.1.

3D structure databases

ProteinModelPortalQ1GGQ1.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1GGQ1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4078062.
GenomeReviewsGene locus TM1040_1432 in contig CP000377_GR.
KEGGsit:TM1040_1432.
NMPDRfig|292414.1.peg.3465.
PATRIC23387022. VBIRueSp69653_2330.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAVMALEMS.
PhylomeDBQ1GGQ1.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycSSP292414:TM1040_1432-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_SILST
AccessionPrimary (citable) accession number: Q1GGQ1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 27, 2006
Last modified: January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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