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Q1GGK7

- PUR5_RUEST

UniProt

Q1GGK7 - PUR5_RUEST

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Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Ruegeria sp. (strain TM1040) (Silicibacter sp.)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRSP292414:GHCT-1502-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
Alternative name(s):
AIR synthaseUniRule annotation
AIRSUniRule annotation
Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
Gene namesi
Name:purMUniRule annotation
Ordered Locus Names:TM1040_1476
OrganismiRuegeria sp. (strain TM1040) (Silicibacter sp.)
Taxonomic identifieri292414 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRuegeria
ProteomesiUP000000636: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 348348Phosphoribosylformylglycinamidine cyclo-ligasePRO_0000258406Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi292414.TM1040_1476.

Structurei

3D structure databases

ProteinModelPortaliQ1GGK7.
SMRiQ1GGK7. Positions 7-340.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741. AIRS.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1GGK7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTSGKNGLTY ADAGVDIDAG NELVDRIKPA AKRTNRPGVM SGLGGFGALF
60 70 80 90 100
DLKAAGYEDP ILVGATDGVG TKLRIAIDTG LVDGVGIDLV AMCVNDLVCQ
110 120 130 140 150
GAEPLFFLDY FATGKLETDV AARIIEGIAE GCVRSGCALI GGETAEMPGM
160 170 180 190 200
YPKGDFDLAG FAVGAMERGT ALPAGVSEGD VLLGLASDGV HSNGYSLVRQ
210 220 230 240 250
IVKYSGLGWD GDNPFGEGKL GEALLTPTRL YVKQSLAAVR AGGVNALAHI
260 270 280 290 300
TGGGLTENLP RVLPDDLGAD IDLGAWELPG VFKWMAQTGG IEESEMLKTF
310 320 330 340
NCGIGMILVV KADRADALTE VLEGEGETVA RLGTVTRGEG IRYTGALL
Length:348
Mass (Da):35,929
Last modified:June 27, 2006 - v1
Checksum:iE4053F41C370CE14
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000377 Genomic DNA. Translation: ABF64209.1.
RefSeqiWP_011538811.1. NC_008044.1.
YP_613471.1. NC_008044.1.

Genome annotation databases

EnsemblBacteriaiABF64209; ABF64209; TM1040_1476.
GeneIDi4077773.
KEGGisit:TM1040_1476.
PATRICi23387118. VBIRueSp69653_2377.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000377 Genomic DNA. Translation: ABF64209.1 .
RefSeqi WP_011538811.1. NC_008044.1.
YP_613471.1. NC_008044.1.

3D structure databases

ProteinModelPortali Q1GGK7.
SMRi Q1GGK7. Positions 7-340.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 292414.TM1040_1476.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABF64209 ; ABF64209 ; TM1040_1476 .
GeneIDi 4077773.
KEGGi sit:TM1040_1476.
PATRICi 23387118. VBIRueSp69653_2377.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci RSP292414:GHCT-1502-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741. AIRS.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TM1040.

Entry informationi

Entry nameiPUR5_RUEST
AccessioniPrimary (citable) accession number: Q1GGK7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: June 27, 2006
Last modified: October 29, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3