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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Ruegeria sp. (strain TM1040) (Silicibacter sp.)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-lysyl-[protein].UniRule annotation
L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-arginyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:TM1040_1519
OrganismiRuegeria sp. (strain TM1040) (Silicibacter sp.)
Taxonomic identifieri292414 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRuegeria
Proteomesi
  • UP000000636 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002581021 – 210Leucyl/phenylalanyl-tRNA--protein transferaseAdd BLAST210

Proteomic databases

PRIDEiQ1GGG4

Interactioni

Protein-protein interaction databases

STRINGi292414.TM1040_1519

Structurei

3D structure databases

ProteinModelPortaliQ1GGG4
SMRiQ1GGG4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R4Z Bacteria
COG2360 LUCA
HOGENOMiHOG000102326
KOiK00684
OMAiYRQGIFP
OrthoDBiPOG091H045I

Family and domain databases

HAMAPiMF_00688 Leu_Phe_trans, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR004616 Leu/Phe-tRNA_Trfase
PANTHERiPTHR30098 PTHR30098, 1 hit
PfamiView protein in Pfam
PF03588 Leu_Phe_trans, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
TIGRFAMsiTIGR00667 aat, 1 hit

Sequencei

Sequence statusi: Complete.

Q1GGG4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLSADLLLH AYANGVFPMA ESRDDPEVFW VDPKRRGILP LDGFRISRSL
60 70 80 90 100
AKRLRRDDYS ISVNRDFAGV VQGCADREET WINGEIFDRY QELHHDGFAH
110 120 130 140 150
SLEVWMDDAL VGGVYGVSLG GAFFGESMFS RRRDASKIAL AYLVDRLNAG
160 170 180 190 200
GYILCDTQFI TPHLASLGGR EISRAAYRRR LAEALDQPGD FISPALPSPQ
210
VLLQRRTQTS
Length:210
Mass (Da):23,538
Last modified:June 27, 2006 - v1
Checksum:i01CF9EBD47EFA0A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000377 Genomic DNA Translation: ABF64252.1
RefSeqiWP_011538853.1, NC_008044.1

Genome annotation databases

EnsemblBacteriaiABF64252; ABF64252; TM1040_1519
KEGGisit:TM1040_1519

Similar proteinsi

Entry informationi

Entry nameiLFTR_RUEST
AccessioniPrimary (citable) accession number: Q1GGG4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: June 27, 2006
Last modified: May 23, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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