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Q1GG88 (Q1GG88_SILST) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable L-aspartate dehydrogenase HAMAP MF_01265
EC=1.4.1.21 HAMAP MF_01265
Gene names
Name:nadX HAMAP MF_01265
Ordered Locus Names:TM1040_1595
OrganismSilicibacter sp. (strain TM1040) [Complete proteome] [HAMAP]
Taxonomic identifier292414 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Ruegeria

Protein attributes

Sequence length262 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate By similarity. HAMAP MF_01265

Catalytic activity

L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H. HAMAP MF_01265

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. HAMAP MF_01265

Miscellaneous

The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia By similarity. HAMAP MF_01265

Sequence similarities

Belongs to the L-aspartate dehydrogenase family. HAMAP MF_01265

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2151 By similarity HAMAP MF_01265
Binding site1191NAD; via amide nitrogen By similarity HAMAP MF_01265
Binding site1851NAD By similarity HAMAP MF_01265

Sequences

Sequence LengthMass (Da)Tools
Q1GG88 [UniParc].

Last modified June 27, 2006. Version 1.
Checksum: 0F8E6E962CD51405

FASTA26227,162
        10         20         30         40         50         60 
MKIGIIGAGA IAQYVAQQLR LRGLGPHVIL ARSAPPPEAQ EALDGVDYVQ RVQNLPQDIS 

        70         80         90        100        110        120 
VMVDCAGHGA LVQHGAALLE RGIALVTLSL GALADDALHA DLERAARAGK TRLHLASGAI 

       130        140        150        160        170        180 
GALDCLRAAK VGGLADVVYV GRKPPQAWRG SVAEHVLELD GLRSPATHFR GSAREAAIAY 

       190        200        210        220        230        240 
PKNANVAAAV ALAGTGFDTT RVELIADPSA RVNIHEIQAH GDFGSFHFRI EGNALPDNPR 

       250        260 
SSALAAMSAV AAIERACAAI IT

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References

[1]"Complete sequence of chromosome of Silicibacter sp. TM1040."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Goodwin L., Thompson L.S., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Belas R., Moran M.A., Buchan A., Gonzalez J.M., Schell M.A., Sun F., Richardson P.
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TM1040.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000377 Genomic DNA. Translation: ABF64328.1.
RefSeqYP_613590.1. NC_008044.1.

3D structure databases

ProteinModelPortalQ1GG88.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ1GG88.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4078404.
GenomeReviewsGene locus TM1040_1595 in contig CP000377_GR.
KEGGsit:TM1040_1595.
PATRIC23387360. VBIRueSp69653_2496.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1712.
HOGENOMHBG649642.
OMAECAGHSA.
ProtClustDBPRK13303.

Enzyme and pathway databases

BioCycSSP292414:TM1040_1595-MONOMER.

Family and domain databases

HAMAPMF_01265. NadX.
[Tree]
InterProIPR005106. Asp/hSer_DH_NAD-bd.
IPR002811. Asp_DH.
IPR011182. Asp_DH_NAD_syn.
IPR020626. Asp_DH_NAD_syn_prok.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK06989.
PfamPF01958. DUF108. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFPIRSF005227. Asp_dh_NAD_syn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ1GG88_SILST
AccessionPrimary (citable) accession number: Q1GG88
Entry history
Integrated into UniProtKB/TrEMBL: June 27, 2006
Last sequence update: June 27, 2006
Last modified: December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info