ID   Q1GD86_RUEST            Unreviewed;       464 AA.
AC   Q1GD86;
DT   27-JUN-2006, integrated into UniProtKB/TrEMBL.
DT   27-JUN-2006, sequence version 1.
DT   27-MAR-2024, entry version 94.
DE   SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:ABF65380.1};
GN   OrderedLocusNames=TM1040_2648 {ECO:0000313|EMBL:ABF65380.1};
OS   Ruegeria sp. (strain TM1040) (Silicibacter sp.).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Ruegeria.
OX   NCBI_TaxID=292414 {ECO:0000313|EMBL:ABF65380.1, ECO:0000313|Proteomes:UP000000636};
RN   [1] {ECO:0000313|Proteomes:UP000000636}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TM1040 {ECO:0000313|Proteomes:UP000000636};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Brettin T., Bruce D., Han C., Tapia R., Goodwin L., Thompson L.S.,
RA   Gilna P., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA   Belas R., Moran M.A., Buchan A., Gonzalez J.M., Schell M.A., Sun F.,
RA   Richardson P.;
RT   "Complete sequence of chromosome of Silicibacter sp. TM1040.";
RL   Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ABF65380.1, ECO:0000313|Proteomes:UP000000636}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TM1040 {ECO:0000313|EMBL:ABF65380.1,
RC   ECO:0000313|Proteomes:UP000000636};
RX   PubMed=17526795; DOI=10.1128/AEM.02580-06;
RA   Moran M.A., Belas R., Schell M.A., Gonzalez J.M., Sun F., Sun S.,
RA   Binder B.J., Edmonds J., Ye W., Orcutt B., Howard E.C., Meile C.,
RA   Palefsky W., Goesmann A., Ren Q., Paulsen I., Ulrich L.E., Thompson L.S.,
RA   Saunders E., Buchan A.;
RT   "Ecological genomics of marine Roseobacters.";
RL   Appl. Environ. Microbiol. 73:4559-4569(2007).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000377; ABF65380.1; -; Genomic_DNA.
DR   RefSeq; WP_011539962.1; NC_008044.1.
DR   AlphaFoldDB; Q1GD86; -.
DR   STRING; 292414.TM1040_2648; -.
DR   KEGG; sit:TM1040_2648; -.
DR   eggNOG; COG2114; Bacteria.
DR   HOGENOM; CLU_033715_2_0_5; -.
DR   OrthoDB; 341967at2; -.
DR   Proteomes; UP000000636; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF17; BLL5647 PROTEIN; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000636};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        47..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        98..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        136..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        159..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          277..408
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   464 AA;  51748 MW;  BF700A44EF5E1342 CRC64;
     MADVALTKAD PPARASLDPI LQDDALQSQH IHAALEEHKK RGVEMAVLAR WIIMPMVAVF
     LIAVYPEPSQ LYYVALLALL CVNGFFIRRF ARVGRSRAEL GLIMLDLVLM TFGMVVPNPF
     DPNEMPVPML YQYDNFMYFF IILATGALAY SWRTVMAIGV WASVIWLGAA GLMWAFMTPD
     EELARRLSEV LVDWPHVQDL YNPNDVGFRF RIQEAMVFLM VAAILAQSTR RFYLMLDQNA
     DLARERANLS RYFSPNVVDQ LSQNDEAISQ VRTSRIAILF VDIVGFTRLA EHRDAVEVIE
     LLRGFHGRME AEVFRHGGTL DKYLGDGLMA TFGTPAPGPQ DASDALACAR AMCAVLDQWN
     AERRATGEPE IHAGIGIHFG EAVQGDIGAN RLEYAVIGTA VNIASRLEGM TRPMQARIVM
     SDALYRRVQE EGGAAALLRG FHCTPEQTIR GLQEPMPVWA LTSL
//