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Q1GCI4 (Q1GCI4_SILST) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323

EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:TM1040_2900
OrganismSilicibacter sp. (strain TM1040) [Complete proteome] [HAMAP]
Taxonomic identifier292414 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRuegeria

Protein attributes

Sequence length354 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2221Iron By similarity HAMAP MF_00323
Metal binding3031Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
Q1GCI4 [UniParc].

Last modified June 27, 2006. Version 1.
Checksum: B3D2BA2238B184C6

FASTA35440,435
        10         20         30         40         50         60 
MLDATSTATR PDNAPADHPP VKAEKVGILL ANLGTPDHYS YWPMRRYLNE FLSDKRVIDY 

        70         80         90        100        110        120 
PSWKWQPLLQ LIILTKRPFA SGEAYKSIWN HERGESPLMT ITKDQTNAMA KAMEELYGDQ 

       130        140        150        160        170        180 
VMVDFCMRYG NPSTKSKVEK MIAAGCRKIL FVPLYPHYAG ATSATANDQF FRVLMEQPWQ 

       190        200        210        220        230        240 
PAVRTIEPYF DQPEYIDALA RSVEDAYAKL DKTPDILVCS YHGMPKRYLM QGDPYHCQCQ 

       250        260        270        280        290        300 
KTTRLLRERL GWDESKIMTT FQSVFGPEEW LRPYTVEHVA ELAKQGKKNI AVIAPAFSAD 

       310        320        330        340        350 
CIETLEEINE EIFESFEHAG GEEFTYIPCL NDSEAHIAAL SSVIRNNLKG WLEA 

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References

[1]"Complete sequence of chromosome of Silicibacter sp. TM1040."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Goodwin L., Thompson L.S., Gilna P. expand/collapse author list , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Belas R., Moran M.A., Buchan A., Gonzalez J.M., Schell M.A., Sun F., Richardson P.
Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TM1040.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000377 Genomic DNA. Translation: ABF65632.1.
RefSeqYP_614894.1. NC_008044.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ1GCI4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4078578.
GenomeReviewsGene locus TM1040_2900 in contig CP000377_GR.
KEGGsit:TM1040_2900.
NMPDRfig|292414.1.peg.1800.
PATRIC23390103. VBIRueSp69653_3850.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMAIRPAKSA.
PhylomeDBQ1GCI4.
ProtClustDBPRK00035.

Enzyme and pathway databases

BioCycSSP292414:TM1040_2900-MONOMER.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ1GCI4_SILST
AccessionPrimary (citable) accession number: Q1GCI4
Entry history
Integrated into UniProtKB/TrEMBL: June 27, 2006
Last sequence update: June 27, 2006
Last modified: December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)