Q1GC77 (Q1GC77_RUEST) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Urocanate hydratase EMBL ABF65739.1
EC=4.2.1.49 EMBL ABF65739.1

Gene names

Ordered Locus Names:

TM1040_3007 EMBL ABF65739.1

Organism

Ruegeria sp. (strain TM1040) (Silicibacter sp.) [Complete proteome] [HAMAP] EMBL ABF65739.1

Taxonomic identifier

292414 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Ruegeria

Protein attributes

Sequence length	562 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate = urocanate + H2O. SAAS SAAS000193
Cofactor	Binds 1 NAD per subunit By similarity.
Pathway	Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 2/3. SAAS SAAS000193

Ontologies

Keywords
Biological process	Histidine metabolism SAAS SAAS000193
Ligand	NAD SAAS SAAS000193
Molecular function	Lyase SAAS SAAS000193 EMBL ABF65739.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	histidine catabolic process to glutamate and formamide Inferred from electronic annotation. Source: UniProtKB-UniPathway histidine catabolic process to glutamate and formate Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	urocanate hydratase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1GC77 [UniParc]. Last modified June 27, 2006. Version 1. Checksum: D7AD7D77A5C57719	FASTA	562	61,654
	10 20 30 40 50 60 MSDPRKNTRD IFPATGTEIT AKSWLTEAPM RMLMNNLHPD VAENPHELVV YGGIGRAART 70 80 90 100 110 120 WQDFDLIVET LKTLEEDQTL MVQSGKPVGV FQTHKDAPRV LIANSNLVPH WANWDHFNEL 130 140 150 160 170 180 DKKGLMMYGQ MTAGSWIYIG TQGIVQGTYE TFAEAGRQHY GGDLTGKWIL TGGLGGMGGA 190 200 210 220 230 240 QPLAAVFAGA CCLAVECNPD SIDFRLRTKY LDEKAETLDE ALEMIERWTK AGEAKSVGLL 250 260 270 280 290 300 GNAADVFAEL VERAKAGGMR PDIVTDQTSA HDPVNGYLPQ GWTMAEWREK RETDKKAVEK 310 320 330 340 350 360 ASRASMKAHV KAMVDFHEMG IPTVDYGNNI RQVALEEGLE TAFSFPGFVP AYIRPLFCKG 370 380 390 400 410 420 IGPFRWCALS GDPEDIRKTD AKMKELFPEN ESLHRWLDMA QDRIAFQGLP ARICWIGLGD 430 440 450 460 470 480 RHKAGLAFNE MVRNGELSAP VVIGRDHLDS GSVASPNRET EAMMDGSDAV SDWPLLNALL 490 500 510 520 530 540 NTASGATWVS LHHGGGVGMG FSQHSGVVIC CDGTEDADRR IGRVLWNDPA TGVMRHADAG 550 560 YEIAKDCAKE HGLNLPGILR SE

References

[1]

"Complete sequence of chromosome of Silicibacter sp. TM1040." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Brettin T., Bruce D., Han C., Tapia R., Goodwin L., Thompson L.S., Gilna P. , Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Belas R., Moran M.A., Buchan A., Gonzalez J.M., Schell M.A., Sun F., Richardson P. Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TM1040.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000377 Genomic DNA. Translation: ABF65739.1.
RefSeq	YP_615001.1. NC_008044.1.
3D structure databases
ProteinModelPortal	Q1GC77.
SMR	Q1GC77. Positions 16-558.
ModBase	Search...
Protein-protein interaction databases
STRING	292414.TM1040_3007.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABF65739; ABF65739; TM1040_3007.
GeneID	4076580.
KEGG	sit:TM1040_3007.
PATRIC	23390317. VBIRueSp69653_3957.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2987.
HOGENOM	HOG000237606.
KO	K01712.
OMA	IRQMAFE.
ProtClustDB	PRK05414.
Enzyme and pathway databases
BioCyc	RSP292414:GHCT-3058-MONOMER.
UniPathway	UPA00379; UER00550.
Family and domain databases
InterPro	IPR000193. Urocanase. IPR023636. Urocanase_CS. IPR023637. Urocanase_dom. [Graphical view]
PANTHER	PTHR32312. PTHR32312. 1 hit.
Pfam	PF01175. Urocanase. 1 hit. [Graphical view]
PIRSF	PIRSF001423. Urocanate_hydrat. 1 hit.
SUPFAM	SSF111326. Urocanase. 1 hit.
TIGRFAMs	TIGR01228. hutU. 1 hit.
PROSITE	PS01233. UROCANASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q1GC77_RUEST

Accession

Primary (citable) accession number: Q1GC77

Entry history

Integrated into UniProtKB/TrEMBL:	June 27, 2006
Last sequence update:	June 27, 2006
Last modified:	May 1, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)