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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei572 – 5721UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciLDEL390333:GIXG-497-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Ldb0501
OrganismiLactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778)
Taxonomic identifieri390333 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000001259 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 909909Phosphoenolpyruvate carboxylasePRO_1000025563Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi390333.Ldb0501.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1GBD4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAKKLENNS NHAVTAEEVK ILTDLLDEST RHLVGDEEFA KIKGLVKIAA
60 70 80 90 100
SSDHSQLESQ IACLSNQEMI IVARYFATLP LLINITEDVD LATEVNLLNN
110 120 130 140 150
TDKDYLGKLE STVDLVAEKD NAAEILSHVN VVPVLTAHPT QVQRKTILEL
160 170 180 190 200
TNKIHDQLRR HRDVKASTIN RKEWTNQLRR YIEIIMQTDI IREKKLKVSN
210 220 230 240 250
EIKNVMVYYP GSLIPAITKL TARYKELARE KGLNVDGATP ITMGMWIGGD
260 270 280 290 300
RDGNPYVTAE TLRLSATIQS EVIFEYYVKA LNDLYRTVSV STSYVQPTPE
310 320 330 340 350
VAELAKLSAD NSPFRENEPY RRAFYYLESR LAHTEMELLD VFSKEAVVKK
360 370 380 390 400
EAALKAPVYK DAYEFKKDLE AIKRSLIQNH DRAVTGGHFD ALLEAIDVFG
410 420 430 440 450
FHLATIDMRQ DSSVNEACVA ELLKSARICD NYSDLDEEEK IQILLSELNN
460 470 480 490 500
DPRSLHSSNS PKSELLQREL KIYHTARLLK DTLGENVIKQ HIISHTESIS
510 520 530 540 550
DMLEQAIMLK EYGLLDSEKA RVQVVPLFET VEDLQNSREI MKRYLSFDIV
560 570 580 590 600
KRWVASKGNY QEIMLGYSDS NKDGGYLASC WNLYKAQTEL TAIGEEQGIK
610 620 630 640 650
ITFMHGRGGT VGRGGGPSYE AITSQPFGSI KDRIRTTEQG EIIQNKYGNK
660 670 680 690 700
DAAYYNLEML VSAAVDRMVS KQKVSQDHIQ DFTASMDGIV EDSNRVYREL
710 720 730 740 750
VFDNPHFHDY FFQATPIKEV SSLNIGSRPA ARKKITELSG LRAIPWVFSW
760 770 780 790 800
SQSRVMFPGW YGVGSAFKHF IDADPNNLKE LQEMYQGWPF FHSLLSNVDM
810 820 830 840 850
VLSKSNMEIA EKYADLCEDE ATRSVFDIIK KEWELTKEVI LQIEGHSKLL
860 870 880 890 900
EDNPSLERSL DYRLPYFNVL NYVQLEMIKR GRQEKLSGIY ESIIHITING

VASGLRNSG
Length:909
Mass (Da):103,282
Last modified:June 26, 2006 - v1
Checksum:i3A40C3CD76549A2F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR954253 Genomic DNA. Translation: CAI97332.1.
RefSeqiYP_618606.1. NC_008054.1.

Genome annotation databases

EnsemblBacteriaiCAI97332; CAI97332; Ldb0501.
KEGGildb:Ldb0501.
PATRICi22216604. VBILacDel123523_0450.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR954253 Genomic DNA. Translation: CAI97332.1.
RefSeqiYP_618606.1. NC_008054.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi390333.Ldb0501.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAI97332; CAI97332; Ldb0501.
KEGGildb:Ldb0501.
PATRICi22216604. VBILacDel123523_0450.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciLDEL390333:GIXG-497-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778.

Entry informationi

Entry nameiCAPP_LACDA
AccessioniPrimary (citable) accession number: Q1GBD4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 14, 2008
Last sequence update: June 26, 2006
Last modified: March 31, 2015
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.