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Q1GBD4 (CAPP_LACDA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:Ldb0501
OrganismLactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081) [Complete proteome] [HAMAP]
Taxonomic identifier390333 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Protein attributes

Sequence length909 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 909909Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_1000025563

Sites

Active site1381 By similarity
Active site5721 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1GBD4 [UniParc].

Last modified June 27, 2006. Version 1.
Checksum: 3A40C3CD76549A2F

FASTA909103,282
        10         20         30         40         50         60 
MTAKKLENNS NHAVTAEEVK ILTDLLDEST RHLVGDEEFA KIKGLVKIAA SSDHSQLESQ 

        70         80         90        100        110        120 
IACLSNQEMI IVARYFATLP LLINITEDVD LATEVNLLNN TDKDYLGKLE STVDLVAEKD 

       130        140        150        160        170        180 
NAAEILSHVN VVPVLTAHPT QVQRKTILEL TNKIHDQLRR HRDVKASTIN RKEWTNQLRR 

       190        200        210        220        230        240 
YIEIIMQTDI IREKKLKVSN EIKNVMVYYP GSLIPAITKL TARYKELARE KGLNVDGATP 

       250        260        270        280        290        300 
ITMGMWIGGD RDGNPYVTAE TLRLSATIQS EVIFEYYVKA LNDLYRTVSV STSYVQPTPE 

       310        320        330        340        350        360 
VAELAKLSAD NSPFRENEPY RRAFYYLESR LAHTEMELLD VFSKEAVVKK EAALKAPVYK 

       370        380        390        400        410        420 
DAYEFKKDLE AIKRSLIQNH DRAVTGGHFD ALLEAIDVFG FHLATIDMRQ DSSVNEACVA 

       430        440        450        460        470        480 
ELLKSARICD NYSDLDEEEK IQILLSELNN DPRSLHSSNS PKSELLQREL KIYHTARLLK 

       490        500        510        520        530        540 
DTLGENVIKQ HIISHTESIS DMLEQAIMLK EYGLLDSEKA RVQVVPLFET VEDLQNSREI 

       550        560        570        580        590        600 
MKRYLSFDIV KRWVASKGNY QEIMLGYSDS NKDGGYLASC WNLYKAQTEL TAIGEEQGIK 

       610        620        630        640        650        660 
ITFMHGRGGT VGRGGGPSYE AITSQPFGSI KDRIRTTEQG EIIQNKYGNK DAAYYNLEML 

       670        680        690        700        710        720 
VSAAVDRMVS KQKVSQDHIQ DFTASMDGIV EDSNRVYREL VFDNPHFHDY FFQATPIKEV 

       730        740        750        760        770        780 
SSLNIGSRPA ARKKITELSG LRAIPWVFSW SQSRVMFPGW YGVGSAFKHF IDADPNNLKE 

       790        800        810        820        830        840 
LQEMYQGWPF FHSLLSNVDM VLSKSNMEIA EKYADLCEDE ATRSVFDIIK KEWELTKEVI 

       850        860        870        880        890        900 
LQIEGHSKLL EDNPSLERSL DYRLPYFNVL NYVQLEMIKR GRQEKLSGIY ESIIHITING 


VASGLRNSG 

« Hide

References

[1]"The complete genome sequence of Lactobacillus bulgaricus reveals extensive and ongoing reductive evolution."
van de Guchte M., Penaud S., Grimaldi C., Barbe V., Bryson K., Nicolas P., Robert C., Oztas S., Mangenot S., Couloux A., Loux V., Dervyn R., Bossy R., Bolotin A., Batto J.-M., Walunas T., Gibrat J.-F., Bessieres P. expand/collapse author list , Weissenbach J., Ehrlich S.D., Maguin E.
Proc. Natl. Acad. Sci. U.S.A. 103:9274-9279(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 11842 / DSM 20081.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR954253 Genomic DNA. Translation: CAI97332.1.
RefSeqYP_618606.1. NC_008054.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING390333.Ldb0501.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAI97332; CAI97332; Ldb0501.
GeneID4085087.
KEGGldb:Ldb0501.
PATRIC22216604. VBILacDel123523_0450.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2352.
HOGENOMHOG000238647.
KOK01595.
OMAAIPWVFG.
OrthoDBEOG6TJ7T8.
ProtClustDBPRK00009.

Enzyme and pathway databases

BioCycLDEL390333:GIXG-497-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_LACDA
AccessionPrimary (citable) accession number: Q1GBD4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 27, 2006
Last modified: February 19, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families