Q1GBC1 (Q1GBC1_LACDA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Uridine kinase HAMAP-Rule MF_00551
EC=2.7.1.48 HAMAP-Rule MF_00551

Alternative name(s):
Cytidine monophosphokinase HAMAP-Rule MF_00551
Uridine monophosphokinase HAMAP-Rule MF_00551

Gene names

Name:	udk1 EMBL CAI97347.1
Synonyms:	udk HAMAP-Rule MF_00551
Ordered Locus Names:	Ldb0516

Organism

Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081) [Complete proteome] [HAMAP]

Taxonomic identifier

390333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus › Lactobacillus delbrueckii › Lactobacillus delbrueckii subsp. bulgaricus

Protein attributes

Sequence length	217 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + cytidine = ADP + CMP. HAMAP-Rule MF_00551 RuleBase RU003825 ATP + uridine = ADP + UMP. HAMAP-Rule MF_00551 RuleBase RU003825
Pathway	Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3. HAMAP-Rule MF_00551 RuleBase RU003825 Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1. HAMAP-Rule MF_00551 RuleBase RU003825
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00551.
Sequence similarities	Belongs to the uridine kinase family. HAMAP-Rule MF_00551 RuleBase RU003824

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP-Rule MF_00551
Ligand	ATP-binding HAMAP-Rule MF_00551 SAAS SAAS000764 RuleBase RU003528 Nucleotide-binding
Molecular function	Kinase HAMAP-Rule MF_00551 SAAS SAAS000764 RuleBase RU003528 EMBL CAI97347.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	CTP salvage Inferred from electronic annotation. Source: UniProtKB-UniPathway UMP salvage Inferred from electronic annotation. Source: UniProtKB-UniPathway
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP phosphotransferase activity, alcohol group as acceptor Inferred from electronic annotation. Source: InterPro uridine kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	14 – 21	8	ATP By similarity HAMAP-Rule MF_00551

Sequences

	Sequence		Length	Mass (Da)
	Q1GBC1 [UniParc]. Last modified June 27, 2006. Version 1. Checksum: 5413C0746D7A734B	FASTA	217	24,866
	10 20 30 40 50 60 MSKKQHPIII GIAGGSGSGK TTIAHELYDQ FKTDRIRIIT EDSYYKNHPE MSMAERNKIN 70 80 90 100 110 120 FDHPDAFDTE LLISQLQDLL NGKAIEMPIY DFTTHLRSPE TVHVEPADII ILEGILVLAS 130 140 150 160 170 180 EELRNLMDIK IFVDTDDDIR LIRRQRRDMA ERGRSFDSII DQYLATVKPS YHQFVEPSKR 190 200 210 YANIIVPEGG ANDVALDMLI TKVRDILRRN DLAEKEA

References

[1]

"The complete genome sequence of Lactobacillus bulgaricus reveals extensive and ongoing reductive evolution." van de Guchte M., Penaud S., Grimaldi C., Barbe V., Bryson K., Nicolas P., Robert C., Oztas S., Mangenot S., Couloux A., Loux V., Dervyn R., Bossy R., Bolotin A., Batto J.-M., Walunas T., Gibrat J.-F., Bessieres P. , Weissenbach J., Ehrlich S.D., Maguin E. Proc. Natl. Acad. Sci. U.S.A. 103:9274-9279(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 11842 / DSM 20081.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR954253 Genomic DNA. Translation: CAI97347.1.
RefSeq	YP_618619.1. NC_008054.1.
3D structure databases
ProteinModelPortal	Q1GBC1.
ModBase	Search...
Protein-protein interaction databases
STRING	390333.Ldb0516.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAI97347; CAI97347; Ldb0516.
GeneID	4083866.
KEGG	ldb:Ldb0516.
PATRIC	22216636. VBILacDel123523_0466.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0572.
HOGENOM	HOG000262756.
KO	K00876.
OMA	RKTVRPM.
ProtClustDB	PRK05480.
Enzyme and pathway databases
BioCyc	LDEL390333:GIXG-512-MONOMER.
UniPathway	UPA00574; UER00637. UPA00579; UER00640.
Family and domain databases
HAMAP	MF_00551. Uridine_kinase.
InterPro	IPR006083. PRK/URK. IPR000764. Uridine_kinase. [Graphical view]
Pfam	PF00485. PRK. 1 hit. [Graphical view]
PRINTS	PR00988. URIDINKINASE.
TIGRFAMs	TIGR00235. udk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q1GBC1_LACDA

Accession

Primary (citable) accession number: Q1GBC1

Entry history

Integrated into UniProtKB/TrEMBL:	June 27, 2006
Last sequence update:	June 27, 2006
Last modified:	May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)