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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei142GTPUniRule annotation1
Binding sitei146GTPUniRule annotation1
Binding sitei190GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi24 – 28GTPUniRule annotation5
Nucleotide bindingi111 – 113GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:Ldb0744Imported
OrganismiLactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778)Imported
Taxonomic identifieri390333 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000001259 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi390333.Ldb0744

Structurei

3D structure databases

ProteinModelPortaliQ1GAT2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 208TubulinInterPro annotationAdd BLAST193
Domaini210 – 327Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q1GAT2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALDFTFDSD DNNNAVIKVI GVGGAGGNAV NRMIEDGVQG VSFIAANTDV
60 70 80 90 100
QALNSNNAEV KIQLGPKLTR GLGAGSHPET GQKAAEESEE TIEDALKGAD
110 120 130 140 150
MIFITAGMGG GTGTGAAPVI AQIARETGAL TVGVVTRPFS FEGPKRSKNA
160 170 180 190 200
AEGIDKLKEY VDTLVIVANN RLLEIVDKKT PMMEALKEAD NVLKQGVQGI
210 220 230 240 250
SDLITSTDYV NLDFADVKTV MENQGAALMG IGRASGENRT VEATKMAISS
260 270 280 290 300
PLLEVSIDGA KQVLLNITGG PDLTLFEAQD ASEIVSTAAG EDVNIIFGTA
310 320 330 340 350
INPNLGDEVV VTVIATGIDD EAEAAASKQF PGRGHQVSAP REKPAAPKIL
360 370 380 390 400
TPEEAAPAAP VQEAPVQAEA AKPTSPVKEE KPAMMDPISV WGLNDDDYSR
410 420 430 440 450
RKKPEEQKRR AEEKEAVSDA DPSSAISQID INTDYDDDDD DDIPFFKHRR

DR
Length:452
Mass (Da):47,752
Last modified:June 27, 2006 - v1
Checksum:i79309A4714DE6D4F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR954253 Genomic DNA Translation: CAI97571.1

Genome annotation databases

EnsemblBacteriaiCAI97571; CAI97571; Ldb0744
KEGGildb:Ldb0744
PATRICifig|390333.13.peg.55

Similar proteinsi

Entry informationi

Entry nameiQ1GAT2_LACDA
AccessioniPrimary (citable) accession number: Q1GAT2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 27, 2006
Last sequence update: June 27, 2006
Last modified: March 28, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health