Q1GAP1 (Q1GAP1_LACDA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrofolate reductase EMBL CAI97615.1
EC=1.5.1.3 EMBL CAI97615.1

Gene names

Name:	folA EMBL CAI97615.1
Ordered Locus Names:	Ldb0788

Organism

Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081) [Complete proteome] [HAMAP]

Taxonomic identifier

390333 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	162 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dihydrofolate reductase family. RuleBase RU004474

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL CAI97615.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1GAP1 [UniParc]. Last modified June 27, 2006. Version 1. Checksum: CDC550C4BF9C6E94	FASTA	162	18,151
	10 20 30 40 50 60 MLSYVWAEDE KGAIGYQGRL PWHLPADLAH FKAKTMGHPM LMGRKTFESL PGLLPGRQHV 70 80 90 100 110 120 VLSTRKLDLP AGVLQLKSEE EVSAWLKEQA GEVCVIGGSS LFALLADQVD KLEVTRIKGI 130 140 150 160 FSADTYMPNL DWAAFALVKS EAHRADGKNK YDYVFETYLR KK

References

[1]

"The complete genome sequence of Lactobacillus bulgaricus reveals extensive and ongoing reductive evolution." van de Guchte M., Penaud S., Grimaldi C., Barbe V., Bryson K., Nicolas P., Robert C., Oztas S., Mangenot S., Couloux A., Loux V., Dervyn R., Bossy R., Bolotin A., Batto J.-M., Walunas T., Gibrat J.-F., Bessieres P. , Weissenbach J., Ehrlich S.D., Maguin E. Proc. Natl. Acad. Sci. U.S.A. 103:9274-9279(2006) [PubMed: 16754859] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR954253 Genomic DNA. Translation: CAI97615.1.
RefSeq	YP_618849.1. NC_008054.1.
3D structure databases
ProteinModelPortal	Q1GAP1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1GAP1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4083932.
GenomeReviews	Gene locus Ldb0788 in contig CR954253_GR.
KEGG	ldb:Ldb0788.
PATRIC	22217183. VBILacDel123523_0735.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0262.
HOGENOM	HBG665708.
OMA	QDEEGVI.
PhylomeDB	Q1GAP1.
ProtClustDB	CLSK925341.
Family and domain databases
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR017925. DHFR_CS. IPR001796. DHFR_dom. [Graphical view]
Gene3D	G3DSA:3.40.430.10. G3DSA:3.40.430.10. 1 hit.
KO	K00287.
PANTHER	PTHR11549:SF1. DHFR. 1 hit.
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PIRSF	PIRSF000194. DHFR. 1 hit.
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS00075. DHFR_1. 1 hit. PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q1GAP1_LACDA

Accession

Primary (citable) accession number: Q1GAP1

Entry history

Integrated into UniProtKB/TrEMBL:	June 27, 2006
Last sequence update:	June 27, 2006
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)