Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q1G9Z4

- BGAL_LACDA

UniProt

Q1G9Z4 - BGAL_LACDA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Beta-galactosidase

Gene

lacZ

Organism
Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei465 – 4651Proton donorBy similarity
Active sitei532 – 5321NucleophileBy similarity

GO - Molecular functioni

  1. beta-galactosidase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Enzyme and pathway databases

BioCyciLDEL390333:GIXG-1187-MONOMER.
SABIO-RKQ1G9Z4.

Protein family/group databases

CAZyiGH2. Glycoside Hydrolase Family 2.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidase (EC:3.2.1.23)
Short name:
Beta-gal
Alternative name(s):
Lactase
Gene namesi
Name:lacZ
Ordered Locus Names:Ldb1201
OrganismiLactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081)
Taxonomic identifieri390333 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000001259: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. beta-galactosidase complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 10081007Beta-galactosidasePRO_0000250751Add
BLAST

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi390333.Ldb1201.

Structurei

3D structure databases

ProteinModelPortaliQ1G9Z4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 2 family.Curated

Phylogenomic databases

eggNOGiCOG3250.
HOGENOMiHOG000252444.
KOiK01190.
OMAiDPKKPYI.
OrthoDBiEOG6XWV0T.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
2.60.40.320. 2 hits.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02929. Bgal_small_N. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view]
PRINTSiPR00132. GLHYDRLASE2.
SMARTiSM01038. Bgal_small_N. 1 hit.
[Graphical view]
SUPFAMiSSF49303. SSF49303. 2 hits.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 1 hit.
PROSITEiPS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q1G9Z4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSNKLVKEKR VDQADLAWLT DPEVYEVNTI PPHSDHESFQ SQEELEEGKS
60 70 80 90 100
SLVQSLDGDW LIDYAENGQG PVNFYAEDFD DSNFKSVKVP GNLELQGFGQ
110 120 130 140 150
PQYVNVQYPW DGSEEIFPPQ IPSKNPLASY VRYFDLDEAF WDKEVSLKFD
160 170 180 190 200
GAATAIYVWL NGHFVGYGED SFTPSEFMVT KFLKKENNRL AVALYKYSSA
210 220 230 240 250
SWLEDQDFWR MSGLFRSVTL QAKPRLHLED LKLTASLTDN YQKGKLEVEA
260 270 280 290 300
NIAYRLPNAS FKLEVRDSEG DLVAEKLGPI RSEQLEFTLA DLPVAAWSAE
310 320 330 340 350
KPNLYQVRLY LYQAGSLLEV SRQEVGFRNF ELKDGIMYLN GQRIVFKGAN
360 370 380 390 400
RHEFDSKLGR AITEEDMIWD IKTMKRSNIN AVRCSHYPNQ SLFYRLCDKY
410 420 430 440 450
GLYVIDEANL ESHGTWEKVG GHEDPSFNVP GDDQHWLGAS LSRVKNMMAR
460 470 480 490 500
DKNHASILIW SLGNESYAGT VFAQMADYVR KADPTRVQHY EGVTHNRKFD
510 520 530 540 550
DATQIESRMY APAKVIEEYL TNKPAKPFIS VEYAHAMGNS VGDLAAYTAL
560 570 580 590 600
EKYPHYQGGF IWDWIDQGLE KDGHLLYGGD FDDRPTDYEF CGNGLVFADR
610 620 630 640 650
TESPKLANVK ALYANLKLEV KDGQLFLKND NLFTNSSSYY FLTSLLVDGK
660 670 680 690 700
LTYQSRPLTF GLEPGESGTF ALPWPEVADE KGEVVYRVTA HLKEDLPWAD
710 720 730 740 750
EGFTVAEAEE VAQKLPEFKP EGRPDLVDSD YNLGLKGNNF QILFSKVKGW
760 770 780 790 800
PVSLKYAGRE YLKRLPEFTF WRALTDNDRG AGYGYDLARW ENAGKYARLK
810 820 830 840 850
DISCEVKEDS VLVKTAFTLP VALKGDLTVT YEVDGRGKIA VTADFPGAEE
860 870 880 890 900
AGLLPAFGLN LALPKELTDY RYYGLGPNES YPDRLEGNYL GIYQGAVKKN
910 920 930 940 950
FSPYLRPQET GNRSKVRWYQ LFDEKGGLEF TANGADLNLS ALPYSAAQIE
960 970 980 990 1000
AADHAFELTN NYTWVRALSA QMGVGGDDSW GQKVHPEFCL DAQKARQLRL

VIQPLLLK
Length:1,008
Mass (Da):114,160
Last modified:January 23, 2007 - v3
Checksum:i4681BFCA448F731F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M55068 Genomic DNA. Translation: AAA25244.1.
CR954253 Genomic DNA. Translation: CAI98003.1.
RefSeqiWP_003619632.1. NC_008054.1.
YP_619096.1. NC_008054.1.

Genome annotation databases

EnsemblBacteriaiCAI98003; CAI98003; Ldb1201.
GeneIDi4085367.
KEGGildb:Ldb1201.
PATRICi22217901. VBILacDel123523_1070.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M55068 Genomic DNA. Translation: AAA25244.1 .
CR954253 Genomic DNA. Translation: CAI98003.1 .
RefSeqi WP_003619632.1. NC_008054.1.
YP_619096.1. NC_008054.1.

3D structure databases

ProteinModelPortali Q1G9Z4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 390333.Ldb1201.

Protein family/group databases

CAZyi GH2. Glycoside Hydrolase Family 2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAI98003 ; CAI98003 ; Ldb1201 .
GeneIDi 4085367.
KEGGi ldb:Ldb1201.
PATRICi 22217901. VBILacDel123523_1070.

Phylogenomic databases

eggNOGi COG3250.
HOGENOMi HOG000252444.
KOi K01190.
OMAi DPKKPYI.
OrthoDBi EOG6XWV0T.

Enzyme and pathway databases

BioCyci LDEL390333:GIXG-1187-MONOMER.
SABIO-RK Q1G9Z4.

Family and domain databases

Gene3Di 2.60.120.260. 1 hit.
2.60.40.320. 2 hits.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
InterProi IPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF02929. Bgal_small_N. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view ]
PRINTSi PR00132. GLHYDRLASE2.
SMARTi SM01038. Bgal_small_N. 1 hit.
[Graphical view ]
SUPFAMi SSF49303. SSF49303. 2 hits.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 1 hit.
PROSITEi PS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Lactose metabolism in Lactobacillus bulgaricus: analysis of the primary structure and expression of the genes involved."
    Leong-Morgenthaler P.M., Zwahlen M.-C., Hottinger H.
    J. Bacteriol. 173:1951-1957(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 11842 / DSM 20081.

Entry informationi

Entry nameiBGAL_LACDA
AccessioniPrimary (citable) accession number: Q1G9Z4
Secondary accession number(s): P20043
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: January 23, 2007
Last modified: October 1, 2014
This is version 56 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3