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Protein
Submitted name:

Putative RNA methylase

Gene

Ldb1411

Organism
Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei279S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei307S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei326S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei379NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotationImported, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Putative RNA methylaseImported
Gene namesi
Ordered Locus Names:Ldb1411Imported
OrganismiLactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778)Imported
Taxonomic identifieri390333 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000001259 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi390333.Ldb1411.

Structurei

3D structure databases

ProteinModelPortaliQ1G9I2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini168 – 437SAM_MT_RSMB_NOPInterPro annotationAdd BLAST270

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CYJ. Bacteria.
COG0144. LUCA.
HOGENOMiHOG000037300.
KOiK03500.
OMAiLRVNRQH.

Family and domain databases

Gene3Di1.10.940.10. 1 hit.
InterProiView protein in InterPro
IPR018314. Fmu/NOL1/Nop2p_CS.
IPR001678. MeTrfase_RsmB/NOP2.
IPR006027. NusB_RsmB_TIM44.
IPR023267. RCMT.
IPR004573. rRNA_ssu_MeTfrase_B.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF01029. NusB. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF48013. SSF48013. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00563. rsmB. 1 hit.
PROSITEiView protein in PROSITE
PS01153. NOL1_NOP2_SUN. 1 hit.
PS51686. SAM_MT_RSMB_NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1G9I2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTNARTVAL DTLMKVINQG SYSNISLNHA LKAAKLPGEE SRLATNLVYG
60 70 80 90 100
TIQYQLYLEY QLKDLVKARL REPYIKPLLL MSAYQIFFLD KVPNRAVLDE
110 120 130 140 150
ANKLAKVYGR PKSSGYRLVN GILHSLLRRG EVLPEKDAPD YLSVKCSMPL
160 170 180 190 200
WLSDYFVANW GKSRAEKIMA SFNSKAKNEI RISALADEKR VVRDLDRAHF
210 220 230 240 250
APQESPLASR SYALSRGGIV MTDFFKDGEV TVQDEAASLV AEAFDFKGNE
260 270 280 290 300
QALDACSAPG GKTIQIAEQL PDGQVTALDI HEKKLRLVKE NAARMRVADR
310 320 330 340 350
VKVKALDARK AREYFSGQEF DKILIDAPCS GLGLLRRKPE IRYTKTAEDI
360 370 380 390 400
SHLAEIQLDI LNEVSGLLKK GGELVYSTCS ISVEENEENV RKFLAAHPDF
410 420 430
ALKPFETAKI SAPKGMLKIL PDSYNSDGFF IAKFTTRG
Length:438
Mass (Da):48,901
Last modified:June 27, 2006 - v1
Checksum:iD3A3BBC6591F221B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR954253 Genomic DNA. Translation: CAI98212.1.
RefSeqiWP_011544040.1. NZ_JQAV01000009.1.

Genome annotation databases

EnsemblBacteriaiCAI98212; CAI98212; Ldb1411.
GeneIDi4084743.
KEGGildb:Ldb1411.
PATRICifig|390333.7.peg.1264.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR954253 Genomic DNA. Translation: CAI98212.1.
RefSeqiWP_011544040.1. NZ_JQAV01000009.1.

3D structure databases

ProteinModelPortaliQ1G9I2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi390333.Ldb1411.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAI98212; CAI98212; Ldb1411.
GeneIDi4084743.
KEGGildb:Ldb1411.
PATRICifig|390333.7.peg.1264.

Phylogenomic databases

eggNOGiENOG4105CYJ. Bacteria.
COG0144. LUCA.
HOGENOMiHOG000037300.
KOiK03500.
OMAiLRVNRQH.

Family and domain databases

Gene3Di1.10.940.10. 1 hit.
InterProiView protein in InterPro
IPR018314. Fmu/NOL1/Nop2p_CS.
IPR001678. MeTrfase_RsmB/NOP2.
IPR006027. NusB_RsmB_TIM44.
IPR023267. RCMT.
IPR004573. rRNA_ssu_MeTfrase_B.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF01029. NusB. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF48013. SSF48013. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00563. rsmB. 1 hit.
PROSITEiView protein in PROSITE
PS01153. NOL1_NOP2_SUN. 1 hit.
PS51686. SAM_MT_RSMB_NOP. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ1G9I2_LACDA
AccessioniPrimary (citable) accession number: Q1G9I2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 27, 2006
Last sequence update: June 27, 2006
Last modified: June 7, 2017
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.