Q1EG59 (Q1EG59_RHIAP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Tryptase inhibitor EMBL AAW32666.1
Organism	Rhipicephalus appendiculatus (Brown ear tick) EMBL AAW32666.1
Taxonomic identifier	34631 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Chelicerata › Arachnida › Acari › Parasitiformes › Ixodida › Ixodoidea › Ixodidae › Rhipicephalinae › Rhipicephalus › Rhipicephalus

Protein attributes

Sequence length	118 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

Ontologies

Keywords
Domain	Signal EMBL AAW32666.1
Technical term	3D-structure PDB 2UUX PDB 2UUY PDB 2LFK PDB 2LFL
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 21	21	Potential EMBL AAW32666.1
	Chain	22 – 118	97	tryptase inhibitor EMBL AAW32666.1		PRO_5000094004

Sequences

	Sequence		Length	Mass (Da)
	Q1EG59 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: A1B78F15E3BFFE25	FASTA	118	13,216
	10 20 30 40 50 60 MGRTTLIVAI VLVAFVASTL GNAYPKVEER RNRPNWDFGK RKEECTVPIG WSEPVKGLCK 70 80 90 100 110 ARFTRYYCMG NCCKVYEGCY TGGYSRMGEC ARNCPGFKRP TPGFRPRHGL ENGTEPGP

References

[1]	"A tick protein with a modified Kunitz fold inhibits human tryptase." Paesen G.C., Siebold C., Harlos K., Peacey M.F., Nuttall P.A., Stuart D.I. J. Mol. Biol. 368:1172-1186(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Salivary glands EMBL AAW32666.1.
[2]	"Oxidative folding and structural analyses of a Kunitz-related inhibitor and its disulfide intermediates: functional implications." Bronsoms S., Pantoja-Uceda D., Gabrijelcic-Geiger D., Sanglas L., Aviles F.X., Santoro J., Sommerhoff C.P., Arolas J.L. J. Mol. Biol. 414:427-441(2011) [PubMed] [Europe PMC] [Abstract] Cited for: STRUCTURE BY NMR OF 42-96.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AY710292 mRNA. Translation: AAW32666.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2LFK	NMR	-	A	42-96	[»]
2LFL	NMR	-	A	42-96	[»]
2UUX	X-ray	1.40	A	44-96	[»]
2UUY	X-ray	1.15	B	45-95	[»]

ProteinModelPortal

Q1EG59.

SMR

Q1EG59. Positions 44-96.

ModBase

Search...

Protein family/group databases

MEROPS

I02.053.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

ProtoNet

Search...

Other

EvolutionaryTrace

Q1EG59.

Entry information

Entry name

Q1EG59_RHIAP

Accession

Primary (citable) accession number: Q1EG59

Entry history

Integrated into UniProtKB/TrEMBL:	July 11, 2006
Last sequence update:	July 11, 2006
Last modified:	October 3, 2012
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)