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Protein

Abscisic acid receptor PYL7

Gene

PYL7

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei65ABABy similarity1
Sitei66Involved in ABA bindingBy similarity1
Sitei92Involved in interactions with PP2CsBy similarity1
Sitei112Involved in ABA bindingBy similarity1
Binding sitei145ABABy similarity1
Sitei156Involved in interactions with PP2CsBy similarity1
Sitei164Involved in ABA bindingBy similarity1
Sitei167Involved in ABA bindingBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionProtein phosphatase inhibitor, Receptor
Biological processAbscisic acid signaling pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Abscisic acid receptor PYL7
Alternative name(s):
ABI1-binding protein 7
PYR1-like protein 7
Regulatory components of ABA receptor 2
Gene namesi
Name:PYL7
Synonyms:ABIP7, RCAR2
Ordered Locus Names:At4g01026
ORF Names:F3I3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G01026.
TAIRilocus:505006424. AT4G01026.

Subcellular locationi

  • Cytoplasm By similarity
  • Nucleus By similarity
  • Cell membrane By similarity

  • Note: Localizes at the plasma membrane in the presence of a CAR protein.By similarity

GO - Cellular componenti

  • cytoplasm Source: UniProtKB
  • nucleus Source: TAIR
  • plasma membrane Source: UniProtKB-SubCell

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003917421 – 211Abscisic acid receptor PYL7Add BLAST211

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi31 ↔ 161ReversibleBy similarity
Disulfide bondi36 ↔ 161ReversibleBy similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ1ECF1.

Expressioni

Gene expression databases

ExpressionAtlasiQ1ECF1. baseline and differential.
GenevisibleiQ1ECF1. AT.

Interactioni

Subunit structurei

Homodimer. Binds ABA on one subunit only. Binds to CARs protein in an ABA-independent manner, both at the plasma membrane and in the nucleus (By similarity). Interacts with ABI1, and possibly with other PP2Cs (PubMed:19874541).By similarity1 Publication

GO - Molecular functioni

Protein-protein interaction databases

BioGridi13214. 6 interactors.
IntActiQ1ECF1. 2 interactors.
STRINGi3702.AT4G01026.1.

Structurei

3D structure databases

ProteinModelPortaliQ1ECF1.
SMRiQ1ECF1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni29 – 180START-likeAdd BLAST152
Regioni93 – 98ABA bindingBy similarity6
Regioni120 – 126ABA bindingBy similarity7

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi89 – 93Gate loopBy similarity5
Motifi119 – 121Latch loopBy similarity3

Domaini

Upon interaction with ABA, the 'latch' and 'gate' loops change in conformation leading to a tight dimerization and the creation a surface that enables the receptor to dock into and inhibit the PP2C active site.By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG410JSF3. Eukaryota.
ENOG41108V9. LUCA.
HOGENOMiHOG000238422.
InParanoidiQ1ECF1.
KOiK14496.
OMAiCTSVLVK.
OrthoDBiEOG09360OHL.
PhylomeDBiQ1ECF1.

Family and domain databases

Gene3Di3.30.530.20. 1 hit.
InterProiView protein in InterPro
IPR019587. Polyketide_cyclase/dehydratase.
IPR023393. START-like_dom.
PfamiView protein in Pfam
PF10604. Polyketide_cyc2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1ECF1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEMIGGDDTD TEMYGALVTA QSLRLRHLHH CRENQCTSVL VKYIQAPVHL
60 70 80 90 100
VWSLVRRFDQ PQKYKPFISR CTVNGDPEIG CLREVNVKSG LPATTSTERL
110 120 130 140 150
EQLDDEEHIL GINIIGGDHR LKNYSSILTV HPEMIDGRSG TMVMESFVVD
160 170 180 190 200
VPQGNTKDDT CYFVESLIKC NLKSLACVSE RLAAQDITNS IATFCNASNG
210
YREKNHTETN L
Length:211
Mass (Da):23,676
Last modified:July 11, 2006 - v1
Checksum:i6381793C94A43C32
GO

Sequence cautioni

The sequence AAM65054 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence CAB45785 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene At4g01020 has been split into 2 genes: At4g01020 and At4g01026.Curated
The sequence CAB80911 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene At4g01020 has been split into 2 genes: At4g01020 and At4g01026.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL080237 Genomic DNA. Translation: CAB45785.1. Sequence problems.
AL161491 Genomic DNA. Translation: CAB80911.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE81969.1.
BT025783 mRNA. Translation: ABF83673.1.
AY087511 mRNA. Translation: AAM65054.1. Different initiation.
PIRiT10542.
RefSeqiNP_567208.1. NM_116332.4.
UniGeneiAt.19744.
At.75231.

Genome annotation databases

EnsemblPlantsiAT4G01026.1; AT4G01026.1; AT4G01026.
GeneIDi827923.
GrameneiAT4G01026.1; AT4G01026.1; AT4G01026.
KEGGiath:AT4G01026.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiPYL7_ARATH
AccessioniPrimary (citable) accession number: Q1ECF1
Secondary accession number(s): Q8LAZ6, Q9SV27
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 2, 2010
Last sequence update: July 11, 2006
Last modified: June 7, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families