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Q1ECF1

- PYL7_ARATH

UniProt

Q1ECF1 - PYL7_ARATH

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Protein

Abscisic acid receptor PYL7

Gene

PYL7

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli

Functioni

Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA (By similarity).By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei65 – 651ABABy similarity
Sitei92 – 921Involved in interactions with PP2CsBy similarity
Binding sitei145 – 1451ABABy similarity
Sitei156 – 1561Involved in interactions with PP2CsBy similarity

GO - Molecular functioni

  1. abscisic acid binding Source: UniProtKB
  2. protein homodimerization activity Source: UniProtKB
  3. receptor activity Source: UniProtKB

GO - Biological processi

  1. abscisic acid-activated signaling pathway Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Receptor

Keywords - Biological processi

Abscisic acid signaling pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Abscisic acid receptor PYL7
Alternative name(s):
ABI1-binding protein 7
PYR1-like protein 7
Regulatory components of ABA receptor 2
Gene namesi
Name:PYL7
Synonyms:ABIP7, RCAR2
Ordered Locus Names:At4g01026
ORF Names:F3I3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 4

Organism-specific databases

TAIRiAT4G01026.

Subcellular locationi

Cytoplasm By similarity. Nucleus By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB
  2. nucleus Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 211211Abscisic acid receptor PYL7PRO_0000391742Add
BLAST

Proteomic databases

PRIDEiQ1ECF1.

Expressioni

Gene expression databases

GenevestigatoriQ1ECF1.

Interactioni

Subunit structurei

Homodimer. Binds ABA on one subunit only (By similarity). Interacts with ABI1, and possibly with other PP2Cs.By similarity1 Publication

Protein-protein interaction databases

BioGridi13214. 5 interactions.
IntActiQ1ECF1. 2 interactions.
STRINGi3702.AT4G01026.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ1ECF1.
SMRiQ1ECF1. Positions 21-186.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni29 – 180152START-likeAdd
BLAST
Regioni93 – 986ABA bindingBy similarity
Regioni120 – 1267ABA bindingBy similarity

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi89 – 935Gate loopBy similarity
Motifi119 – 1213Latch loopBy similarity

Domaini

Upon interaction with ABA, the 'latch' and 'gate' loops change in conformation leading to a tight dimerization and the creation a surface that enables the receptor to dock into and inhibit the PP2C active site.By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG303563.
HOGENOMiHOG000238422.
InParanoidiQ1ECF1.
KOiK14496.
OMAiEHILGIN.
PhylomeDBiQ1ECF1.

Family and domain databases

Gene3Di3.30.530.20. 1 hit.
InterProiIPR019587. Polyketide_cyclase/dehydratase.
IPR023393. START-like_dom.
[Graphical view]
PfamiPF10604. Polyketide_cyc2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1ECF1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEMIGGDDTD TEMYGALVTA QSLRLRHLHH CRENQCTSVL VKYIQAPVHL
60 70 80 90 100
VWSLVRRFDQ PQKYKPFISR CTVNGDPEIG CLREVNVKSG LPATTSTERL
110 120 130 140 150
EQLDDEEHIL GINIIGGDHR LKNYSSILTV HPEMIDGRSG TMVMESFVVD
160 170 180 190 200
VPQGNTKDDT CYFVESLIKC NLKSLACVSE RLAAQDITNS IATFCNASNG
210
YREKNHTETN L
Length:211
Mass (Da):23,676
Last modified:July 11, 2006 - v1
Checksum:i6381793C94A43C32
GO

Sequence cautioni

The sequence AAM65054.1 differs from that shown. Reason: Erroneous initiation.
The sequence CAB45785.1 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene At4g01020 has been split into 2 genes: At4g01020 and At4g01026.
The sequence CAB80911.1 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene At4g01020 has been split into 2 genes: At4g01020 and At4g01026.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL080237 Genomic DNA. Translation: CAB45785.1. Sequence problems.
AL161491 Genomic DNA. Translation: CAB80911.1. Sequence problems.
CP002687 Genomic DNA. Translation: AEE81969.1.
BT025783 mRNA. Translation: ABF83673.1.
AY087511 mRNA. Translation: AAM65054.1. Different initiation.
PIRiT10542.
RefSeqiNP_567208.1. NM_116332.3.
UniGeneiAt.19744.
At.75231.

Genome annotation databases

EnsemblPlantsiAT4G01026.1; AT4G01026.1; AT4G01026.
GeneIDi827923.
KEGGiath:AT4G01026.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL080237 Genomic DNA. Translation: CAB45785.1 . Sequence problems.
AL161491 Genomic DNA. Translation: CAB80911.1 . Sequence problems.
CP002687 Genomic DNA. Translation: AEE81969.1 .
BT025783 mRNA. Translation: ABF83673.1 .
AY087511 mRNA. Translation: AAM65054.1 . Different initiation.
PIRi T10542.
RefSeqi NP_567208.1. NM_116332.3.
UniGenei At.19744.
At.75231.

3D structure databases

ProteinModelPortali Q1ECF1.
SMRi Q1ECF1. Positions 21-186.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 13214. 5 interactions.
IntActi Q1ECF1. 2 interactions.
STRINGi 3702.AT4G01026.1-P.

Proteomic databases

PRIDEi Q1ECF1.

Protocols and materials databases

DNASUi 827923.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT4G01026.1 ; AT4G01026.1 ; AT4G01026 .
GeneIDi 827923.
KEGGi ath:AT4G01026.

Organism-specific databases

TAIRi AT4G01026.

Phylogenomic databases

eggNOGi NOG303563.
HOGENOMi HOG000238422.
InParanoidi Q1ECF1.
KOi K14496.
OMAi EHILGIN.
PhylomeDBi Q1ECF1.

Gene expression databases

Genevestigatori Q1ECF1.

Family and domain databases

Gene3Di 3.30.530.20. 1 hit.
InterProi IPR019587. Polyketide_cyclase/dehydratase.
IPR023393. START-like_dom.
[Graphical view ]
Pfami PF10604. Polyketide_cyc2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
    Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B.
    , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
    Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Arabidopsis ORF clones."
    Kim C.J., Chen H., Quinitio C., Shinn P., Ecker J.R.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Full-length cDNA from Arabidopsis thaliana."
    Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  5. "PYR/PYL/RCAR family members are major in-vivo ABI1 protein phosphatase 2C-interacting proteins in Arabidopsis."
    Nishimura N., Sarkeshik A., Nito K., Park S.-Y., Wang A., Carvalho P.C., Lee S., Caddell D.F., Cutler S.R., Chory J., Yates J.R., Schroeder J.I.
    Plant J. 61:290-299(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH ABI1, IDENTIFICATION BY MASS SPECTROMETRY.
  6. "Regulators of PP2C phosphatase activity function as abscisic acid sensors."
    Ma Y., Szostkiewicz I., Korte A., Moes D., Yang Y., Christmann A., Grill E.
    Science 324:1064-1068(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY.
  7. Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiPYL7_ARATH
AccessioniPrimary (citable) accession number: Q1ECF1
Secondary accession number(s): Q8LAZ6, Q9SV27
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 2, 2010
Last sequence update: July 11, 2006
Last modified: October 29, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3