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Protein

Endochitinase 1

Gene

CTS1

Organism
Coccidioides immitis (strain RS) (Valley fever fungus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Chitin degradation, Polysaccharide degradation
LigandChitin-binding

Protein family/group databases

CAZyiGH18. Glycoside Hydrolase Family 18.

Names & Taxonomyi

Protein namesi
Recommended name:
Endochitinase 1 (EC:3.2.1.14)
Alternative name(s):
Complement-fixation antigen
Short name:
CF-AG
Short name:
CF-antigen
Gene namesi
Name:CTS1
ORF Names:CIMG_02795
OrganismiCoccidioides immitis (strain RS) (Valley fever fungus)
Taxonomic identifieri246410 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesOnygenales incertae sedisCoccidioides
Proteomesi
  • UP000001261 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:CIMG_02795.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17By similarityAdd BLAST17
ChainiPRO_000025228618 – 427Endochitinase 1Add BLAST410

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi387N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi246410.XP_001249024.1.

Structurei

3D structure databases

ProteinModelPortaliQ1E3R8.
SMRiQ1E3R8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG2806. Eukaryota.
COG3325. LUCA.
InParanoidiQ1E3R8.
KOiK01183.
OrthoDBiEOG092C2AAM.

Family and domain databases

InterProiView protein in InterPro
IPR011583. Chitinase_II.
IPR029070. Chitinase_insertion_sf.
IPR001223. Glyco_hydro18_cat.
IPR001579. Glyco_hydro_18_chit_AS.
IPR017853. Glycoside_hydrolase_SF.
PfamiView protein in Pfam
PF00704. Glyco_hydro_18. 1 hit.
SMARTiView protein in SMART
SM00636. Glyco_18. 1 hit.
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF54556. SSF54556. 1 hit.
PROSITEiView protein in PROSITE
PS01095. CHITINASE_18. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q1E3R8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFLIGALLT LQTLVQASSM SSMPNSYPVP EAPAEGGFRS VVYFVNWAIY
60 70 80 90 100
GRGHNPQDLK ADQFTHILYA FANIRPSGEV YLSDTWADTD KHYPGDKWDE
110 120 130 140 150
PGNNVYGCIK QMYLLKKNNR NLKTLLSIGG WTYSPNFKTP ASTEEGRKKF
160 170 180 190 200
ADTSLKLMKD LGFDGIDIDW EYPEDEKQAN DFVLLLKACR EALDAYSAKH
210 220 230 240 250
PNGKKFLLTI ASPAGPQNYN KLKLAEMDKY LDFWNLMAYD FSGSWDKVSG
260 270 280 290 300
HMSNVFPSTT KPESTPFSSD KAVKDYIKAG VPANKIVLGM PLYGRAFAST
310 320 330 340 350
DGIGTSFNGV GGGSWENGVW DYKDMPQQGA QVTELEDIAA SYSYDKNKRY
360 370 380 390 400
LISYDTVKIA GKKAEYITKN GMGGGMWWES SSDKTGNESL VGTVVNGLGG
410 420
TGKLEQRENE LSYPESVYDN LKNGMPS
Length:427
Mass (Da):47,398
Last modified:July 11, 2006 - v1
Checksum:iF55F6DF8D0FCB15D
GO

Sequence cautioni

The sequence BAE20296 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BAE20297 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BAE20299 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BAE20300 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BAE20303 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG704911 Genomic DNA. Translation: EAS37441.1.
AB232752 Genomic DNA. Translation: BAE20296.1. Sequence problems.
AB232753 Genomic DNA. Translation: BAE20297.1. Sequence problems.
AB232755 Genomic DNA. Translation: BAE20299.1. Sequence problems.
AB232756 Genomic DNA. Translation: BAE20300.1. Sequence problems.
AB232759 Genomic DNA. Translation: BAE20303.1. Sequence problems.
AJ408865 Genomic DNA. Translation: CAC29131.1.
AJ408866 Genomic DNA. Translation: CAC29132.1.
AJ408867 Genomic DNA. Translation: CAC29133.1.
RefSeqiXP_001249024.1. XM_001249023.2.

Genome annotation databases

EnsemblFungiiEAS37441; EAS37441; CIMG_02795.
GeneIDi4566471.
KEGGicim:CIMG_02795.

Similar proteinsi

Entry informationi

Entry nameiCHI1_COCIM
AccessioniPrimary (citable) accession number: Q1E3R8
Secondary accession number(s): J3KAA2, Q400W2, Q9C0M7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: July 11, 2006
Last modified: November 22, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families