ID   Q1DFW6_MYXXD            Unreviewed;       530 AA.
AC   Q1DFW6;
DT   11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2006, sequence version 1.
DT   27-MAR-2024, entry version 93.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:ABF91199.1};
GN   OrderedLocusNames=MXAN_0174 {ECO:0000313|EMBL:ABF91199.1};
OS   Myxococcus xanthus (strain DK1622).
OC   Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC   Myxococcaceae; Myxococcus.
OX   NCBI_TaxID=246197 {ECO:0000313|EMBL:ABF91199.1, ECO:0000313|Proteomes:UP000002402};
RN   [1] {ECO:0000313|EMBL:ABF91199.1, ECO:0000313|Proteomes:UP000002402}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DK1622 {ECO:0000313|Proteomes:UP000002402};
RX   PubMed=17015832; DOI=10.1073/pnas.0607335103;
RA   Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S.,
RA   Eisen J.A., Ronning C.M., Barbazuk W.B., Blanchard M., Field C.,
RA   Halling C., Hinkle G., Iartchuk O., Kim H.S., Mackenzie C., Madupu R.,
RA   Miller N., Shvartsbeyn A., Sullivan S.A., Vaudin M., Wiegand R.,
RA   Kaplan H.B.;
RT   "Evolution of sensory complexity recorded in a myxobacterial genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15200-15205(2006).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000113; ABF91199.1; -; Genomic_DNA.
DR   RefSeq; WP_011550321.1; NC_008095.1.
DR   AlphaFoldDB; Q1DFW6; -.
DR   STRING; 246197.MXAN_0174; -.
DR   EnsemblBacteria; ABF91199; ABF91199; MXAN_0174.
DR   GeneID; 41357677; -.
DR   KEGG; mxa:MXAN_0174; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_27_7; -.
DR   OrthoDB; 5503993at2; -.
DR   Proteomes; UP000002402; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002402};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        175..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          200..253
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          258..494
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   530 AA;  56135 MW;  AA10C8BDB933DA98 CRC64;
     MRLKLKQKMM LLPAVVAVFL VAILVAFIAL GARSGGVYAR ISSSQVPTIE LNREVMHRFP
     GLHRNVLAAV AAKAGGLEPL SAEVDELQSK LDLAGAVPDA NRQRVDELKS SLATYWTNSR
     AAVTFAVEGD EKAASALASV ESLAAALSHE LERAVEADGQ AIATSYAEVA GLHRATTWTV
     CVLVLLCIAL TVGLAYWLHR EVTLPLAKLT HVATRIAEKG DLTQAIDVSA HDEVGELARG
     FQVMVTRLRN VPTTIQTVVT DLTNAAKTLT QASQEQVNFL TNQSRSLTEA STTIAEIAQT
     SSMAASRAEM VLRVAGQADA FSASGQESIE KSAEGLQQIR QRVGALVGSI AHLSDQAVHA
     GEIIGSVKDL ADQSNVLALN AAIEAARAGE QGRGFAVVAR EMRSLSGQSL QSTQRIGKIL
     LEINQAIRQT VGIAEGDSEK MEEGIEQVLA SANTLKEITT VVQESSQAAR QIVASVTQQN
     AGIAQMTEVM TTLSSMMADV VTATMTAEQA VTQINASLGQ LHELSTGFRV
//