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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Myxococcus xanthus (strain DK 1622)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-lysyl-[protein].UniRule annotation
L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-arginyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BioCyciMXAN246197:G1G53-1283-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:MXAN_1311
OrganismiMyxococcus xanthus (strain DK 1622)
Taxonomic identifieri246197 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeMyxococcaceaeMyxococcus
Proteomesi
  • UP000002402 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002580661 – 234Leucyl/phenylalanyl-tRNA--protein transferaseAdd BLAST234

Interactioni

Protein-protein interaction databases

STRINGi246197.MXAN_1311

Structurei

3D structure databases

ProteinModelPortaliQ1DCQ5
SMRiQ1DCQ5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R4Z Bacteria
COG2360 LUCA
HOGENOMiHOG000102326
KOiK00684
OMAiYRQGIFP
OrthoDBiPOG091H045I

Family and domain databases

HAMAPiMF_00688 Leu_Phe_trans, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR004616 Leu/Phe-tRNA_Trfase
PANTHERiPTHR30098 PTHR30098, 1 hit
PfamiView protein in Pfam
PF03588 Leu_Phe_trans, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
TIGRFAMsiTIGR00667 aat, 1 hit

Sequencei

Sequence statusi: Complete.

Q1DCQ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPIYLLSDEH PELFPPPERA DKSGVVAVGG DLRPERLLAA YARGIFPWYS
60 70 80 90 100
EGDPILWHSP DPRFVLSPDK LHVGRSLRKT MARGIYEVRY DTAFRRVITE
110 120 130 140 150
CSQVPRPGQT GTWITEEMME AYVTLHEAGF AHSVEAWAEG ELKGGLYGVS
160 170 180 190 200
LGAAFFGESM FALAPDASKV AFVTAAERFQ GWGFQLIDCQ VETEHLARFG
210 220 230
AENWPRRRFL SALARAMKEP TRRGKWTEGA AADP
Length:234
Mass (Da):26,158
Last modified:July 11, 2006 - v1
Checksum:iAE5F6E8062BBC729
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000113 Genomic DNA Translation: ABF90423.1
RefSeqiWP_011551428.1, NC_008095.1

Genome annotation databases

EnsemblBacteriaiABF90423; ABF90423; MXAN_1311
KEGGimxa:MXAN_1311

Similar proteinsi

Entry informationi

Entry nameiLFTR_MYXXD
AccessioniPrimary (citable) accession number: Q1DCQ5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: July 11, 2006
Last modified: February 28, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome