Q1DC08 (Q1DC08_MYXXD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alkyl hydroperoxide reductase AhpD HAMAP MF_01676
EC=1.11.1.15 HAMAP MF_01676

Alternative name(s):
Alkylhydroperoxidase AhpD HAMAP MF_01676

Gene names

Name:	ahpD HAMAP MF_01676
Ordered Locus Names:	MXAN_1563

Organism

Myxococcus xanthus (strain DK 1622) [Complete proteome] [HAMAP] EMBL ABF90463.1

Taxonomic identifier

246197 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Myxococcales › Cystobacterineae › Myxococcaceae › Myxococcus

Protein attributes

Sequence length	174 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity By similarity. HAMAP MF_01676 SAAS SAAS004674
Catalytic activity	2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. HAMAP MF_01676 SAAS SAAS004674
Sequence similarities	Belongs to the AhpD family. HAMAP MF_01676

Ontologies

Keywords
Domain	Redox-active center HAMAP MF_01676 SAAS SAAS004674
Molecular function	Antioxidant HAMAP MF_01676 SAAS SAAS004674 Oxidoreductase Peroxidase HAMAP MF_01676 SAAS SAAS004674
PTM	Disulfide bond HAMAP MF_01676 SAAS SAAS004674
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	alkyl hydroperoxide reductase activity Inferred from electronic annotation. Source: HAMAP peroxidase activity Inferred from electronic annotation. Source: UniProtKB-KW peroxiredoxin activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	134	1	Proton donor By similarity HAMAP MF_01676
	Active site	137	1	Cysteine sulfenic acid (-SOH) intermediate By similarity HAMAP MF_01676
Amino acid modifications
	Disulfide bond	134 ↔ 137		Alternate By similarity HAMAP MF_01676
	Disulfide bond	137		Interchain (with AhpC); in linked form By similarity HAMAP MF_01676

Sequences

	Sequence		Length	Mass (Da)
	Q1DC08 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: 86B0739278EB7BC6	FASTA	174	18,943
	10 20 30 40 50 60 MASLEVVRSE LADSHKDTRL NLQGVLEGGS LTAEQRWGVA VACAFAARNE RLKEAMLNEA 70 80 90 100 110 120 KKALANPEPV IEDARAAASL MAMNNVYYRF RHMIGKESYS TKRAGLRMNR LAQVLTNKVD 130 140 150 160 170 FELVCLAVSA INGCEMCMQS HEKVVLDGGL SEDQVHDAVR IASVIHAAAV GLES

References

[1]

"Evolution of sensory complexity recorded in a myxobacterial genome." Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S., Eisen J., Ronning C.M., Barbazuk W.B., Blanchard M., Field C., Halling C., Hinkle G., Iartchuk O., Kim H.S., Mackenzie C., Madupu R., Miller N., Shvartsbeyn A. , Sullivan S.A., Vaudin M., Wiegand R., Kaplan H.B. Proc. Natl. Acad. Sci. U.S.A. 103:15200-15205(2006) [PubMed: 17015832] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000113 Genomic DNA. Translation: ABF90463.1.
RefSeq	YP_629815.1. NC_008095.1.
3D structure databases
ProteinModelPortal	Q1DC08.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1DC08.
Protein family/group databases
PeroxiBase	4641. MxAhpD.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4100831.
GenomeReviews	Gene locus MXAN_1563 in contig CP000113_GR.
KEGG	mxa:MXAN_1563.
PATRIC	22645713. VBIMyxXan43560_1554.
TIGR	MXAN_1563.
Phylogenomic databases
eggNOG	COG2128.
HOGENOM	HBG414634.
OMA	RAGLRMN.
ProtClustDB	CLSK944971.
Family and domain databases
HAMAP	MF_01676. AhpD. [Tree]
InterPro	IPR004674. AhpD. IPR004675. AhpD_core. IPR003779. CMD. [Graphical view]
KO	K04756.
Pfam	PF02627. CMD. 1 hit. [Graphical view]
TIGRFAMs	TIGR00778. AhpD_dom. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q1DC08_MYXXD

Accession

Primary (citable) accession number: Q1DC08

Entry history

Integrated into UniProtKB/TrEMBL:	July 11, 2006
Last sequence update:	July 11, 2006
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)