Q1D9W6 (CYSD_MYXXD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sulfate adenylyltransferase subunit 2
EC=2.7.7.4

Alternative name(s):
ATP-sulfurylase small subunit
Sulfate adenylate transferase
Short name=SAT

Gene names

Name:	cysD
Ordered Locus Names:	MXAN_2337

Organism

Myxococcus xanthus (strain DK 1622) [Complete proteome] [HAMAP]

Taxonomic identifier

246197 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Myxococcales › Cystobacterineae › Myxococcaceae › Myxococcus

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of CysD, the smaller subunit, and CysN By similarity.
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 305	305	Sulfate adenylyltransferase subunit 2 HAMAP MF_00064		PRO_0000340208

Sequences

	Sequence		Length	Mass (Da)
	Q1D9W6 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: B6114720DD8F577A	FASTA	305	35,338
	10 20 30 40 50 60 MSEHTFARAS HLSELEAESI HILRETVAEF ANPVMLYSIG KDSQVLLHLA RKAFHPAPLP 70 80 90 100 110 120 FPLLHVDTTW KFRDMYAFRD AFVARHGLRL IIHRNQRALA EGINPFDHGS QKYTHAMKTQ 130 140 150 160 170 180 ALLEALAAHG FDAAFGGARR DEEKSRAKER VFSFRDRHGQ WDPRRQRPEL WNLFNGRVDA 190 200 210 220 230 240 GESMRVFPLS NWTELDVWHY VLRERIPVVP LYFAAERPVI DRGGTLLMVD DERMRLRPGE 250 260 270 280 290 300 KPEIRRVRFR TLGCYPLSGA IESSATTVET VIHEMVNARQ SERQGRLIDH DEEGSMELKK REGYF

References

[1]

"Evolution of sensory complexity recorded in a myxobacterial genome." Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S., Eisen J., Ronning C.M., Barbazuk W.B., Blanchard M., Field C., Halling C., Hinkle G., Iartchuk O., Kim H.S., Mackenzie C., Madupu R., Miller N., Shvartsbeyn A. , Sullivan S.A., Vaudin M., Wiegand R., Kaplan H.B. Proc. Natl. Acad. Sci. U.S.A. 103:15200-15205(2006) [PubMed: 17015832] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DK 1622.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000113 Genomic DNA. Translation: ABF91544.1.
RefSeq	YP_630557.1. NC_008095.1.
3D structure databases
ProteinModelPortal	Q1D9W6.
SMR	Q1D9W6. Positions 4-215.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1D9W6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4106229.
GenomeReviews	Gene locus MXAN_2337 in contig CP000113_GR.
KEGG	mxa:MXAN_2337.
PATRIC	22647203. VBIMyxXan43560_2288.
TIGR	MXAN_2337.
Phylogenomic databases
eggNOG	COG0175.
HOGENOM	HBG758022.
OMA	NARIHPG.
PhylomeDB	Q1D9W6.
ProtClustDB	PRK05253.
Enzyme and pathway databases
BioCyc	MXAN246197:MXAN_2337-MONOMER.
Family and domain databases
HAMAP	MF_00064. Sulf_adenylyltr_sub2. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K00957.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD_MYXXD

Accession

Primary (citable) accession number: Q1D9W6

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	July 11, 2006
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program