Reviewed,
UniProtKB/Swiss-Prot Q1D823 (AGLZ_MYXXD)
Last modified
December 15, 2009.
Version 34.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Adventurous-gliding motility protein Z | ||||
| Gene names |
| ||||
| Organism | Myxococcus xanthus (strain DK 1622) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 246197 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Deltaproteobacteria › Myxococcales › Cystobacterineae › Myxococcaceae › Myxococcus |
Protein attributes
| Sequence length | 1395 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Required for adventurous-gliding motility (A motility), in response to environmental signals sensed by the frz chemosensory system. Forms ordered clusters that span the cell length and that remain stationary relative to the surface across which the cells move, serving as anchor points (focal, transient adhesion sites) that allow the bacterium to move forward. Clusters disassemble at the lagging cell pole. Ref.1 Ref.3 |
| Subunit structure | Interacts with mglA. Ref.1 |
| Subcellular location | Cytoplasm. Note: In motile cells, localizes in ordered clusters spanning the cell length. In stalled cells, localizes at the leading cell pole. Ref.3 |
| Sequence similarities | Contains 1 response regulatory domain. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Domain | Coiled coil |
| Molecular function | Motor protein |
| PTM | Phosphoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro two-component signal transduction system (phosphorelay)Inferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | motor activity Inferred from electronic annotation. Source: UniProtKB-KW two-component response regulator activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 1395 | 1395 | Adventurous-gliding motility protein Z | PRO_0000282834 | |||||
Regions | |||||||||
| Domain | 4 – 122 | 119 | Response regulatory | ||||||
| Coiled coil | 213 – 911 | 699 | Potential | ||||||
| Compositional bias | 123 – 212 | 90 | Pro-rich | ||||||
| Compositional bias | 1095 – 1361 | 267 | Ala-rich | ||||||
Amino acid modifications | |||||||||
| Modified residue | 48 | 1 | 4-aspartylphosphate Potential | ||||||
Experimental info | |||||||||
| Sequence conflict | 763 | 1 | Q → R in AAR39422. Ref.1 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "AglZ is a filament-forming coiled-coil protein required for adventurous gliding motility of Myxococcus xanthus." Yang R., Bartle S., Otto R., Stassinopoulos A.G., Rogers M., Plamann L., Hartzell P.L. J. Bacteriol. 186:6168-6178(2004) [PubMed: 15342587] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, INTERACTION WITH MGLA. |
| [2] | "Evolution of sensory complexity recorded in a myxobacterial genome." Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S., Eisen J., Ronning C.M., Barbazuk W.B., Blanchard M., Field C., Halling C., Hinkle G., Iartchuk O., Kim H.S., Mackenzie C., Madupu R., Miller N., Shvartsbeyn A. Kaplan H.B.Proc. Natl. Acad. Sci. U.S.A. 103:15200-15205(2006) [PubMed: 17015832] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
| [3] | "Evidence that focal adhesion complexes power bacterial gliding motility." Mignot T., Shaevitz J.W., Hartzell P.L., Zusman D.R. Science 315:853-856(2007) [PubMed: 17289998] [Abstract] Cited for: ROLE IN A-TYPE GLIDING MOTILITY, SUBCELLULAR LOCATION. |
Cross-references
Sequence databases | |
|---|---|
| AY487937 Genomic DNA. Translation: AAR39422.1. CP000113 Genomic DNA. Translation: ABF92300.1. | |
| RefSeq | YP_631200.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| IntAct | Q1D823. 9 interactions. |
| STRING | Q1D823. |
Genome annotation databases | |
| GeneID | 4106990. |
| GenomeReviews | Gene locus MXAN_2991 in contig CP000113_GR. |
| KEGG | mxa:MXAN_2991. |
| TIGR | MXAN_2991. |
Phylogenomic databases | |
| OMA | WAANGYL. |
Enzyme and pathway databases | |
| BioCyc | MXAN246197:MXAN_2991-MON. |
Family and domain databases | |
| InterPro | IPR011006. CheY-like. IPR001789. Sig_transdc_resp-reg_receiver. [Graphical view] |
| Pfam | PF00072. Response_reg. 1 hit. [Graphical view] |
| SMART | SM00448. REC. 1 hit. [Graphical view] |
| PROSITE | PS50110. RESPONSE_REGULATORY. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | AGLZ_MYXXD | ||||||||
| Accession | Primary (citable) accession number: Q1D823 Secondary accession number(s): Q6RW49 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Protein Spotlight Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries |
| SIMILARITY comments Index of protein domains and families |

Clusters with


