ID   Q1D222_MYXXD            Unreviewed;       605 AA.
AC   Q1D222;
DT   11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2006, sequence version 1.
DT   27-MAR-2024, entry version 100.
DE   SubName: Full=Chemoreceptor McP2 {ECO:0000313|EMBL:ABF90272.1};
GN   Name=mcP2 {ECO:0000313|EMBL:ABF90272.1};
GN   OrderedLocusNames=MXAN_5148 {ECO:0000313|EMBL:ABF90272.1};
OS   Myxococcus xanthus (strain DK1622).
OC   Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC   Myxococcaceae; Myxococcus.
OX   NCBI_TaxID=246197 {ECO:0000313|EMBL:ABF90272.1, ECO:0000313|Proteomes:UP000002402};
RN   [1] {ECO:0000313|EMBL:ABF90272.1, ECO:0000313|Proteomes:UP000002402}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DK1622 {ECO:0000313|Proteomes:UP000002402};
RX   PubMed=17015832; DOI=10.1073/pnas.0607335103;
RA   Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S.,
RA   Eisen J.A., Ronning C.M., Barbazuk W.B., Blanchard M., Field C.,
RA   Halling C., Hinkle G., Iartchuk O., Kim H.S., Mackenzie C., Madupu R.,
RA   Miller N., Shvartsbeyn A., Sullivan S.A., Vaudin M., Wiegand R.,
RA   Kaplan H.B.;
RT   "Evolution of sensory complexity recorded in a myxobacterial genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15200-15205(2006).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000113; ABF90272.1; -; Genomic_DNA.
DR   RefSeq; WP_011555119.1; NC_008095.1.
DR   AlphaFoldDB; Q1D222; -.
DR   STRING; 246197.MXAN_5148; -.
DR   EnsemblBacteria; ABF90272; ABF90272; MXAN_5148.
DR   GeneID; 41362431; -.
DR   KEGG; mxa:MXAN_5148; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_452514_0_0_7; -.
DR   OrthoDB; 5522708at2; -.
DR   Proteomes; UP000002402; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002402};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        50..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        110..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        134..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        192..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        242..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          266..318
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          323..559
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   605 AA;  63858 MW;  44D3343FB3F819F3 CRC64;
     MSAQKGPRRA SFSRHLMAPV PLANLVGAAL SLRFASLTLA EPLAGRMGLM GILGGALCAT
     ALVSGAAVSL GRQRTLRGLE RGDVPTTPQT LASAVAEVTR APDEAFLGSL GLWLVTTLTL
     GACMWLGVGV ELAVAARIAA LGLLFGPLTA LLVYCLVVLR SRKVVLWLAE LGMTHAQLIE
     AMPRRAELRA RLAAFAFVAV MTPAVLSAQL ASALSNHIFT RLMAERDVSR QLMLAQELRV
     EALTQGGGLV LLVFALALTA AYLGGTMLGR PLRELSREAK RIAEGDLASP RVVPAEDEVW
     DVSAAFTTMR VHLADVMSQL QRAGAQISAT TEEILTTSGR YEAGATEQAS SLDETSATTE
     ELARSARQIA ENAGSVAEIA QRTLGAAQQG QGSAEAFLGS MARMRQDNGA ISSAVVRLNK
     RVQQIGKIVE FINGVADKSE LLALNAELEG TKASEVGRGF SLVAAEMRRL AENVLESTKE
     IEGLIEEVRE ASAAAVSATE GGVRAVETGT TLAQQVSESL RQIVDLAGQT SYAVRSISLA
     TQQQQMGTDQ LADTMADILR ITQQSLNATK QVTTANTDLL VLARDLQGVV ERFQIGQEPL
     GEEGG
//