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Q1CX51 (G6PI_MYXXD) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:MXAN_6908
OrganismMyxococcus xanthus (strain DK 1622) [Complete proteome] [HAMAP]
Taxonomic identifier246197 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeMyxococcaceaeMyxococcus

Protein attributes

Sequence length529 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 529529Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000252631

Sites

Active site3221Proton donor By similarity
Active site3511 By similarity
Active site4551 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q1CX51 [UniParc].

Last modified July 11, 2006. Version 1.
Checksum: 26510B9D51A9DD5A

FASTA52958,323
        10         20         30         40         50         60 
MTERELWERY QRYLCVVPAL DFTLDVSRMR FPADYLERMR PRLEEAFGAM EALEKGAVAN 

        70         80         90        100        110        120 
PDEKRKVGHY WLRAPELAPE PALQKEITDT VAAIHAFAKN VHEGRVKPQK AQRFTHMLIV 

       130        140        150        160        170        180 
GIGGSALGPQ LVADALGTAK DPMQVSFFDN TDPDGFDRVL AQLGERLSET LTLVISKSGG 

       190        200        210        220        230        240 
TKETRNGMLE AERGYSARGL DFSKHAVAVT GAGSELDNHA KKQGWLRAFP MWDWVGGRTS 

       250        260        270        280        290        300 
VTSAVGLLPA RLQGLDIDAL LKGARDMDAA TRERDALKNP AALLALMWHY AGDGRGHKDM 

       310        320        330        340        350        360 
VILPYKDRLL LMSRYLQQLV MESLGKETDL DGQVVNQGIA VYGNKGSTDQ HAYVQQLREG 

       370        380        390        400        410        420 
VLNFFATFIE VLKDRDGGSQ EVEPGVTSGD YLLGFLLGTR RALYEKDRES LTLTVPDVSA 

       430        440        450        460        470        480 
RTLGALIALY ERAVGFYATL VHINAYHQPG VEAGKKAAGV VLELQRKLTT RLREARAEAR 

       490        500        510        520 
TAEQLAADIG MPDEVETVFK VLQHLAANPD RGVTRTPGAT PTQARFQAK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000113 Genomic DNA. Translation: ABF87421.1.
RefSeqYP_635022.1. NC_008095.1.

3D structure databases

ProteinModelPortalQ1CX51.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING246197.MXAN_6908.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABF87421; ABF87421; MXAN_6908.
GeneID4104539.
KEGGmxa:MXAN_6908.
PATRIC22656301. VBIMyxXan43560_6795.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000131425.
KOK01810.
OMARQVGHYW.
OrthoDBEOG64R61J.
ProtClustDBPRK14096.

Enzyme and pathway databases

BioCycMXAN246197:GIWU-6845-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 2 hits.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_MYXXD
AccessionPrimary (citable) accession number: Q1CX51
Entry history
Integrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: July 11, 2006
Last modified: February 19, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways