ID   Q1CX08_MYXXD            Unreviewed;       547 AA.
AC   Q1CX08;
DT   11-JUL-2006, integrated into UniProtKB/TrEMBL.
DT   11-JUL-2006, sequence version 1.
DT   27-MAR-2024, entry version 99.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:ABF87794.1};
GN   OrderedLocusNames=MXAN_6950 {ECO:0000313|EMBL:ABF87794.1};
OS   Myxococcus xanthus (strain DK1622).
OC   Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC   Myxococcaceae; Myxococcus.
OX   NCBI_TaxID=246197 {ECO:0000313|EMBL:ABF87794.1, ECO:0000313|Proteomes:UP000002402};
RN   [1] {ECO:0000313|EMBL:ABF87794.1, ECO:0000313|Proteomes:UP000002402}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DK1622 {ECO:0000313|Proteomes:UP000002402};
RX   PubMed=17015832; DOI=10.1073/pnas.0607335103;
RA   Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S.,
RA   Eisen J.A., Ronning C.M., Barbazuk W.B., Blanchard M., Field C.,
RA   Halling C., Hinkle G., Iartchuk O., Kim H.S., Mackenzie C., Madupu R.,
RA   Miller N., Shvartsbeyn A., Sullivan S.A., Vaudin M., Wiegand R.,
RA   Kaplan H.B.;
RT   "Evolution of sensory complexity recorded in a myxobacterial genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15200-15205(2006).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000113; ABF87794.1; -; Genomic_DNA.
DR   RefSeq; WP_011556871.1; NC_008095.1.
DR   AlphaFoldDB; Q1CX08; -.
DR   SMR; Q1CX08; -.
DR   STRING; 246197.MXAN_6950; -.
DR   EnsemblBacteria; ABF87794; ABF87794; MXAN_6950.
DR   GeneID; 41364128; -.
DR   KEGG; mxa:MXAN_6950; -.
DR   eggNOG; COG0840; Bacteria.
DR   eggNOG; COG5278; Bacteria.
DR   HOGENOM; CLU_000445_107_27_7; -.
DR   OrthoDB; 2489132at2; -.
DR   Proteomes; UP000002402; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd19410; HK9-like_sensor; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR007891; CHASE3.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF05227; CHASE3; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002402};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        180..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          204..256
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          275..511
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
SQ   SEQUENCE   547 AA;  58841 MW;  74569E7B81FF735B CRC64;
     MSIGNRIALG FGLSLLMLLI VAGVSFQGAN QLTTSTAGLL TAHENFRIIR EVRALLMDAE
     SGQRGFILTG DESYLVPYRE AAVALQNDLS RLRDAMADHP NQRARLNRLE PIVTQRVNRL
     EEGIRLRRQE GLEAGAKFIQ AGQGREVMLQ VKQIIDEMLV AEQERWDEHA TAARDMAQRI
     LWVLGIGTLL GVVIVGGGSY IITRGITTPL RALMVGAEQL GRGKLEHRID VKGQDETAQL
     ARAFNDMAEK RQQNEVQLEK ESEQREHTLR TVAEFVNQLA GASAEILSST TEQVAGAQEQ
     GSAVTETVST IEEITKTSEE AAGRARAVSD SARHAEDVGR SGRRAVEEAV GAMGAVREQV
     ESIASRILAL AEQAQAIGDI ITTVNDISEQ THMLALNASI EASRAGEHGR GFAVVASEVK
     ALADQSKKAT GQVRQILGQI QKATHGAVMT TEEGTKSVAT ATRVVSEAGA NIQTLSDLLA
     QASLTAAQIA ASANQQATGI GQIRQAMHDV NQATQQALIS SRQTERAMQD LNGMGQKLKG
     LLGEYGR
//