Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q1CWF0

- Q1CWF0_MYXXD

UniProt

Q1CWF0 - Q1CWF0_MYXXD

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Alanine racemase

Gene

alr

Organism
Myxococcus xanthus (strain DK 1622)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei57 – 571Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei160 – 1601SubstrateUniRule annotation
Active sitei301 – 3011Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei349 – 3491Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciMXAN246197:GIWU-7097-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:MXAN_7160Imported
OrganismiMyxococcus xanthus (strain DK 1622)Imported
Taxonomic identifieri246197 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeMyxococcaceaeMyxococcus
ProteomesiUP000002402: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei57 – 571N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi246197.MXAN_7160.

Structurei

3D structure databases

ProteinModelPortaliQ1CWF0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiFIMSHLA.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1CWF0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAASVVEVNV ESIGSGPGDA VHSSWLELSA SALRHNVAVF RALEGQGAPR
60 70 80 90 100
ALGVVLKGNA YGHGLAQVLP VVHGEVDLLY VIAPQDALKV REYERAQGLG
110 120 130 140 150
PRQVLVLGAV APDEAVVLAR EGVDAVVADR GWADAAAVLR AAKLERPLRV
160 170 180 190 200
HVHLDTGLGR EGFTLEGLPT ESRFLSESRD VLEVVGVLSH FANTEDVTEQ
210 220 230 240 250
GYALAQVDAF EKGLAFLSEQ LAPARPLQRH IAASAATLVL PRARYEALRV
260 270 280 290 300
GISLYGLWPS PETRLSARLV LGEVPVLKPV LSWRCRSQVV KWLSAGSYVG
310 320 330 340 350
YGCTYRCPEP TRIAVLPVGY YDGYPRLVSG KAHVLVNGRR CPVLGRVMMN
360 370 380 390 400
HLIVDVTRAT SDERPVTATL MGRDGEESVP AESLAGWAQT IHYELVTRLG

AHLKRTVVA
Length:409
Mass (Da):44,019
Last modified:July 11, 2006 - v1
Checksum:i32819678F000E814
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000113 Genomic DNA. Translation: ABF93060.1.
RefSeqiYP_635273.1. NC_008095.1.

Genome annotation databases

EnsemblBacteriaiABF93060; ABF93060; MXAN_7160.
GeneIDi4107756.
KEGGimxa:MXAN_7160.
PATRICi22656813. VBIMyxXan43560_7051.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000113 Genomic DNA. Translation: ABF93060.1 .
RefSeqi YP_635273.1. NC_008095.1.

3D structure databases

ProteinModelPortali Q1CWF0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 246197.MXAN_7160.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABF93060 ; ABF93060 ; MXAN_7160 .
GeneIDi 4107756.
KEGGi mxa:MXAN_7160.
PATRICi 22656813. VBIMyxXan43560_7051.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OMAi FIMSHLA.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci MXAN246197:GIWU-7097-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DK 1622Imported.

Entry informationi

Entry nameiQ1CWF0_MYXXD
AccessioniPrimary (citable) accession number: Q1CWF0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 11, 2006
Last sequence update: July 11, 2006
Last modified: November 26, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3