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Q1CWF0

- Q1CWF0_MYXXD

UniProt

Q1CWF0 - Q1CWF0_MYXXD

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Protein
Alanine racemase
Gene
alr, MXAN_7160
Organism
Myxococcus xanthus (strain DK 1622)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei57 – 571Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei160 – 1601Substrate By similarityUniRule annotation
Active sitei301 – 3011Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei349 – 3491Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciMXAN246197:GIWU-7097-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:MXAN_7160Imported
OrganismiMyxococcus xanthus (strain DK 1622)Imported
Taxonomic identifieri246197 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaMyxococcalesCystobacterineaeMyxococcaceaeMyxococcus
ProteomesiUP000002402: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei57 – 571N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi246197.MXAN_7160.

Structurei

3D structure databases

ProteinModelPortaliQ1CWF0.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiFIMSHLA.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1CWF0-1 [UniParc]FASTAAdd to Basket

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MAASVVEVNV ESIGSGPGDA VHSSWLELSA SALRHNVAVF RALEGQGAPR    50
ALGVVLKGNA YGHGLAQVLP VVHGEVDLLY VIAPQDALKV REYERAQGLG 100
PRQVLVLGAV APDEAVVLAR EGVDAVVADR GWADAAAVLR AAKLERPLRV 150
HVHLDTGLGR EGFTLEGLPT ESRFLSESRD VLEVVGVLSH FANTEDVTEQ 200
GYALAQVDAF EKGLAFLSEQ LAPARPLQRH IAASAATLVL PRARYEALRV 250
GISLYGLWPS PETRLSARLV LGEVPVLKPV LSWRCRSQVV KWLSAGSYVG 300
YGCTYRCPEP TRIAVLPVGY YDGYPRLVSG KAHVLVNGRR CPVLGRVMMN 350
HLIVDVTRAT SDERPVTATL MGRDGEESVP AESLAGWAQT IHYELVTRLG 400
AHLKRTVVA 409
Length:409
Mass (Da):44,019
Last modified:July 11, 2006 - v1
Checksum:i32819678F000E814
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000113 Genomic DNA. Translation: ABF93060.1.
RefSeqiYP_635273.1. NC_008095.1.

Genome annotation databases

EnsemblBacteriaiABF93060; ABF93060; MXAN_7160.
GeneIDi4107756.
KEGGimxa:MXAN_7160.
PATRICi22656813. VBIMyxXan43560_7051.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000113 Genomic DNA. Translation: ABF93060.1 .
RefSeqi YP_635273.1. NC_008095.1.

3D structure databases

ProteinModelPortali Q1CWF0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 246197.MXAN_7160.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABF93060 ; ABF93060 ; MXAN_7160 .
GeneIDi 4107756.
KEGGi mxa:MXAN_7160.
PATRICi 22656813. VBIMyxXan43560_7051.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OMAi FIMSHLA.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci MXAN246197:GIWU-7097-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DK 1622Imported.

Entry informationi

Entry nameiQ1CWF0_MYXXD
AccessioniPrimary (citable) accession number: Q1CWF0
Entry historyi
Integrated into UniProtKB/TrEMBL: July 11, 2006
Last sequence update: July 11, 2006
Last modified: July 9, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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