Q1CWA4 (Q1CWA4_MYXXD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Sensor histidine kinase/response regulator EMBL ABF86135.1

Gene names

Ordered Locus Names:

MXAN_7206

Organism

Myxococcus xanthus (strain DK 1622) [Complete proteome] [HAMAP] EMBL ABF86135.1

Taxonomic identifier

246197 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Deltaproteobacteria › Myxococcales › Cystobacterineae › Myxococcaceae › Myxococcus › Myxococcus xanthus

Protein attributes

Sequence length	1379 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 histidine kinase domain. SAAS SAAS004358

Ontologies

Keywords
Molecular function	Kinase EMBL ABF86135.1 Transferase
PTM	Phosphoprotein SAAS SAAS004358
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	intracellular signal transduction Inferred from electronic annotation. Source: GOC regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro signal transduction by phosphorylation Inferred from electronic annotation. Source: GOC
Cellular_component	membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro phosphorelay response regulator activity Inferred from electronic annotation. Source: InterPro phosphorelay sensor kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
itself		3	EBI-1574045,EBI-1574045
MXAN_1679	Q1DBP2	3	EBI-1574045,EBI-1574075
MXAN_2606	Q1D948	3	EBI-1574045,EBI-1574166
MXAN_5314	Q1D1K8	4	EBI-1574045,EBI-1574223

Sequences

	Sequence		Length	Mass (Da)
	Q1CWA4 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: C4DC3B02F4933E9A	FASTA	1,379	148,797
	10 20 30 40 50 60 MASGPFLPDT AGDMRTPGQR ARALGRGFIG WFFVVGLVLA TPGMALDPQR RVSQYSQDMW 70 80 90 100 110 120 RSDDGLPQNS LLSMVQTRDG YLWLGTWEGL ARFDGARFTV FDKRNAPELR NHTIKALAED 130 140 150 160 170 180 ASGTLWVGTG QGLVAYRKGH FERAPGAAAS LDSARVETLV AADGVLWVGT TTGLWQVPLG 190 200 210 220 230 240 EGVARQYTEA DGLPASHITA LTPGEGTSLW VGTPEGLARW VDGRVEPAPF PFPGPESRPY 250 260 270 280 290 300 VMALRRDATG VLWLGTKAGL YSWNGLVASR FTTDEGLPSL SVNALYADGD GNLWVGTHRG 310 320 330 340 350 360 GLTRHNSKGF SEPVPGMEWM AESAVLSLLE DRDGHLWVGT YSGLMRLRDG PFATYGIPEG 370 380 390 400 410 420 LADETVSAVL EDRRGTLWVG TTSGLFRYEN RTFHHVGTEQ GLPESVIPAM HEAHDGTLWV 430 440 450 460 470 480 GTLTGAYRYD GQRFTRVSRA QGLPHDVVTA ILVDSRGDTW LGTQAGLARM HGGGVTVYGP 490 500 510 520 530 540 KHGFTNPIIV MVEDSRGRVW FGSDTGLVRW DGEQKGFQRF TQQDGLPGDL VLALHADPDG 550 560 570 580 590 600 TVWVGTETGL GRWREDTWAR FTVAQGLYDD AVFSLVPDGD GSLWMSSNKG VSRVSRRDLE 610 620 630 640 650 660 DVAAGVRPRL TTMDFDTRDG MRSAECNGNT QPSAWRGEDG RLWFTNLRGA IVVDPVRVRE 670 680 690 700 710 720 SRQPPEVRIE EVRVQGTPVP MEGPVELEPG ASRLEIRFTA FTPVDAARLP FRYRLAGHDD 730 740 750 760 770 780 TWVHAESRRA LYNGLRPGSY RFEVQAKGRD GGWTEPVSLD VVLEPKLWQR TGFWLLCVLG 790 800 810 820 830 840 VGILGVSVYL LRVGQLKDRE RWLAERVKDR TQALARANAE LEANMHTLRQ AQAQLVQTGR 850 860 870 880 890 900 LAAVGQLAAG VGHEINNPLA YIVSNLEHAS EEADALAREL DGTRDVGARL KDVNQALRDA 910 920 930 940 950 960 LLGADRVRRI VQDLKMFSRP DDEKQGPVEL HAVLDSAVKI AMGELRPRAK LVRDYGDVPR 970 980 990 1000 1010 1020 VEGNEARLAQ VFLNLLINAA QALPEGQAGT NEVRLVTRRG PDGRVVTEVR DTGSGISLEL 1030 1040 1050 1060 1070 1080 LGRIFDPFYT TKPVGVGTGL GLSLCHAYLT AMGGTIAVDS EAGRGSVFRV TLRAAAEAQR 1090 1100 1110 1120 1130 1140 VGGDGASVEP PATSDRGVPG AAVPVTPASS GDIATVPDVS VEHGVAASDA TTMRLRGEAA 1150 1160 1170 1180 1190 1200 PRAELDSTPQ ASAPERTQGA GWGITPPQAK STDGRAADSA ALAASQENGG RMAAQNASVT 1210 1220 1230 1240 1250 1260 SGMSRSSEAG TVGSHQGEPS STHASAEGSP PDRMGEDGRF SATEAATRGR VLVVDDDALV 1270 1280 1290 1300 1310 1320 SGAIRRTLAR ENDVDVLVSA RRALEKLTGT EARYDVVLCD LMMPEMTGMD LYDALAQVDS 1330 1340 1350 1360 1370 RAAERIVFIT GGAFTATART FLERVANPRV EKPFDPEALR QLVRSEVARA RREASGRAA

References

[1]

"Evolution of sensory complexity recorded in a myxobacterial genome." Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S., Eisen J., Ronning C.M., Barbazuk W.B., Blanchard M., Field C., Halling C., Hinkle G., Iartchuk O., Kim H.S., Mackenzie C., Madupu R., Miller N., Shvartsbeyn A. , Sullivan S.A., Vaudin M., Wiegand R., Kaplan H.B. Proc. Natl. Acad. Sci. U.S.A. 103:15200-15205(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DK 1622.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000113 Genomic DNA. Translation: ABF86135.1.
RefSeq	YP_635319.1. NC_008095.1.
3D structure databases
ProteinModelPortal	Q1CWA4.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q1CWA4. 33 interactions.
STRING	246197.MXAN_7206.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABF86135; ABF86135; MXAN_7206.
GeneID	4100748.
KEGG	mxa:MXAN_7206.
PATRIC	22656899. VBIMyxXan43560_7094.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0642.
KO	K10819.
OMA	DKEKMAT.
Enzyme and pathway databases
BioCyc	MXAN246197:GIWU-7143-MONOMER.
Family and domain databases
Gene3D	1.10.287.130. 1 hit. 2.120.10.30. 2 hits. 3.30.565.10. 1 hit.
InterPro	IPR011042. 6-blade_b-propeller_TolB-like. IPR011006. CheY-like_superfamily. IPR003594. HATPase_ATP-bd. IPR011110. Reg_prop. IPR004358. Sig_transdc_His_kin-like_C. IPR003661. Sig_transdc_His_kin_sub1_dim/P. IPR005467. Sig_transdc_His_kinase_core. IPR009082. Sig_transdc_His_kinase_dimeric. IPR001789. Sig_transdc_resp-reg_receiver. IPR011123. Y_Y_Y. [Graphical view]
Pfam	PF02518. HATPase_c. 1 hit. PF00512. HisKA. 1 hit. PF07494. Reg_prop. 5 hits. PF00072. Response_reg. 1 hit. PF07495. Y_Y_Y. 1 hit. [Graphical view]
PRINTS	PR00344. BCTRLSENSOR.
SMART	SM00387. HATPase_c. 1 hit. SM00388. HisKA. 1 hit. SM00448. REC. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF52172. CheY_like. 1 hit. SSF47384. His_kin_homodim. 1 hit.
PROSITE	PS50109. HIS_KIN. 1 hit. PS50110. RESPONSE_REGULATORY. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q1CWA4_MYXXD

Accession

Primary (citable) accession number: Q1CWA4

Entry history

Integrated into UniProtKB/TrEMBL:	July 11, 2006
Last sequence update:	July 11, 2006
Last modified:	May 1, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)