Q1CV49 (Q1CV49_HELPH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cystathionine gamma-synthase EMBL ABF84173.1
EC=2.5.1.48 EMBL ABF84173.1

Gene names

Ordered Locus Names:

HPAG1_0106

Organism

Helicobacter pylori (strain HPAG1) [Complete proteome] [HAMAP]

Taxonomic identifier

357544 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter

Protein attributes

Sequence length	380 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Pyridoxal phosphate By similarity. RuleBase RU004507
Sequence similarities	Belongs to the trans-sulfuration enzymes family. RuleBase RU004079

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU004507
Molecular function	Transferase EMBL ABF84173.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular amino acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	cystathionine gamma-synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q1CV49 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: 8DDBAA6425ABEF3E	FASTA	380	41,205
	10 20 30 40 50 60 MRMQTKLIHG GISEDTTTGA VSVPIYQTST YRQDAIGHHK GYEYSRSGNP TRFALEELIA 70 80 90 100 110 120 DLEGGVKGFA FASGLAGIHA VFSLLQSGDH VLLGDDVYGG TFRLFNKVLV KNGLSCTIID 130 140 150 160 170 180 TSDLSQIKKA IKQNTKALYL ETPSNPLLKI TDLAQCASVA KDHGLLTIVD NTFATPYYQN 190 200 210 220 230 240 PLLLGADIVV HSGTKYLGGH SDVVAGLVTT NNEALSQEIA FFQNAIGGVL GPQDSWLLQR 250 260 270 280 290 300 GIKTLALRME AHQKNALCVA EFLEKHPKVE KVYYPGLPTH PNYELAKAQM RGFSGMLSFT 310 320 330 340 350 360 LKNDSEATLF VESLKLFILG ESLGGVESLV GIPAFMTHAC IPKEQREAAG IRDGLVRLSV 370 380 GIEHEQDLLE DLEQAFAKIG

References

[1]

"The complete genome sequence of a chronic atrophic gastritis Helicobacter pylori strain: evolution during disease progression." Oh J.D., Kling-Baeckhed H., Giannakis M., Xu J., Fulton R.S., Fulton L.A., Cordum H.S., Wang C., Elliott G., Edwards J., Mardis E.R., Engstrand L.G., Gordon J.I. Proc. Natl. Acad. Sci. U.S.A. 103:9999-10004(2006) [PubMed: 16788065] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000241 Genomic DNA. Translation: ABF84173.1.
RefSeq	YP_626847.1. NC_008086.1.
3D structure databases
ProteinModelPortal	Q1CV49.
ModBase	Search...
Protein-protein interaction databases
STRING	Q1CV49.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4099199.
GenomeReviews	Gene locus HPAG1_0106 in contig CP000241_GR.
KEGG	hpa:HPAG1_0106.
PATRIC	20601514. VBIHelPyl56048_0110.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0626.
HOGENOM	HBG754729.
OMA	NQYEYSR.
ProtClustDB	PRK06176.
Family and domain databases
InterPro	IPR000277. Cys/Met-Metab_PyrdxlP-dep_enz. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K01760.
PANTHER	PTHR11808. Cys_Met_Meta_PP. 1 hit.
Pfam	PF01053. Cys_Met_Meta_PP. 1 hit. [Graphical view]
PIRSF	PIRSF001434. CGS. 1 hit.
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITE	PS00868. CYS_MET_METAB_PP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q1CV49_HELPH

Accession

Primary (citable) accession number: Q1CV49

Entry history

Integrated into UniProtKB/TrEMBL:	July 11, 2006
Last sequence update:	July 11, 2006
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)