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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Helicobacter pylori (strain HPAG1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei156GTPUniRule annotation1
Binding sitei160GTPUniRule annotation1
Binding sitei204GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi37 – 41GTPUniRule annotation5
Nucleotide bindingi125 – 127GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseImported
Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciHPYL357544:G1G5Q-991-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:HPAG1_0960Imported
OrganismiHelicobacter pylori (strain HPAG1)Imported
Taxonomic identifieri357544 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000008835 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ1CSP5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 222TubulinInterPro annotationAdd BLAST194
Domaini224 – 343Tubulin_CInterPro annotationAdd BLAST120

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili96 – 116Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q1CSP5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHQSEMENY NIGQASIEEV SDPAYKGAKI VVIGVGGGGS NMIKHLVEYG
60 70 80 90 100
VHQDVTPIAT NTDGQHLKNN PAPVKILLGK ESTGGLGAGG VPDIGRKAAE
110 120 130 140 150
ESANEIREAI KDAKLVIIST GLGGGTGTGA TPTIVKIAKE VGALTIAIVT
160 170 180 190 200
KPFKYEGNQK RKRAEEGLKE LEQSSDSILV IPNDKILLTM KKNASTTECY
210 220 230 240 250
REVDDVLVRA VSGISTIITK PGNINVDFAD LKSALGFKGF ALMGIGEATG
260 270 280 290 300
EESAKLAVQN AIQSPLLDDA SIEGAKSIIV FFEHHPDYPM MAYSQACDFI
310 320 330 340 350
QDQAHQDVDV KFGQHTSDNI PIDHVRVTII ATGAERNSGG ASLESIATPS
360 370 380
QPVVKQTRKV GNGEYLKIPT EEELSIPTTM RIQQD
Length:385
Mass (Da):40,968
Last modified:July 11, 2006 - v1
Checksum:iD7738E822E31BBE2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000241 Genomic DNA Translation: ABF85027.1
RefSeqiWP_000233612.1, NC_008086.1

Genome annotation databases

EnsemblBacteriaiABF85027; ABF85027; HPAG1_0960
KEGGihpa:HPAG1_0960

Similar proteinsi

Entry informationi

Entry nameiQ1CSP5_HELPH
AccessioniPrimary (citable) accession number: Q1CSP5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 11, 2006
Last sequence update: July 11, 2006
Last modified: March 28, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health