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Q1CSG4

- GLK_HELPH

UniProt

Q1CSG4 - GLK_HELPH

Protein

Glucokinase

Gene

glk

Organism
Helicobacter pylori (strain HPAG1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (11 Jul 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi12 – 176ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. glucokinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciHPYL357544:GH1F-1067-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GlucokinaseUniRule annotation (EC:2.7.1.2UniRule annotation)
    Alternative name(s):
    Glucose kinaseUniRule annotation
    Gene namesi
    Name:glkUniRule annotation
    Ordered Locus Names:HPAG1_1041
    OrganismiHelicobacter pylori (strain HPAG1)
    Taxonomic identifieri357544 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
    ProteomesiUP000008835: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 336336GlucokinasePRO_0000268775Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi357544.HPAG1_1041.

    Structurei

    3D structure databases

    ProteinModelPortaliQ1CSG4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the bacterial glucokinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0837.
    HOGENOMiHOG000274469.
    KOiK00845.
    OMAiDKAPHSA.
    OrthoDBiEOG64BQ47.

    Family and domain databases

    HAMAPiMF_00524. Glucokinase.
    InterProiIPR003836. Glucokinase.
    [Graphical view]
    PfamiPF02685. Glucokinase. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00749. glk. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q1CSG4-1 [UniParc]FASTAAdd to Basket

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    MPKTETYPRL LADIGGTNAR FGLEVAPRQI ECIEVLRCED FESLSDAVRF    50
    YLSKCKESLK LHPIYGSFAV ATPIMGDFVQ MTNNHWTFSI ETTRQCLTLK 100
    KLLVINDFVA QAYAISAMQE NDLAQIGGIK CEINAPKAIL GPGTGLGVST 150
    LIQNSDGSLK VLPGEGGHVS FAPFDDLEIL VWQYARSKFN HVSAERFLSG 200
    SGLVLIYEAL SKRKGLEKVA KLSKAELTPQ IISERALNGD YPICRLTLDT 250
    FCSMLGTLAA DVALTLGARG GVYLCGGIIP RFIDYFKTSP FRARFETKGR 300
    MGAFLASIPV HVVMKKTPGL DGAGIALENY LLHDKI 336
    Length:336
    Mass (Da):36,732
    Last modified:July 11, 2006 - v1
    Checksum:iEE941BE7411A51A8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000241 Genomic DNA. Translation: ABF85108.1.
    RefSeqiYP_627782.1. NC_008086.1.

    Genome annotation databases

    EnsemblBacteriaiABF85108; ABF85108; HPAG1_1041.
    GeneIDi4099283.
    KEGGihpa:HPAG1_1041.
    PATRICi20603501. VBIHelPyl56048_1082.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000241 Genomic DNA. Translation: ABF85108.1 .
    RefSeqi YP_627782.1. NC_008086.1.

    3D structure databases

    ProteinModelPortali Q1CSG4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 357544.HPAG1_1041.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABF85108 ; ABF85108 ; HPAG1_1041 .
    GeneIDi 4099283.
    KEGGi hpa:HPAG1_1041.
    PATRICi 20603501. VBIHelPyl56048_1082.

    Phylogenomic databases

    eggNOGi COG0837.
    HOGENOMi HOG000274469.
    KOi K00845.
    OMAi DKAPHSA.
    OrthoDBi EOG64BQ47.

    Enzyme and pathway databases

    BioCyci HPYL357544:GH1F-1067-MONOMER.

    Family and domain databases

    HAMAPi MF_00524. Glucokinase.
    InterProi IPR003836. Glucokinase.
    [Graphical view ]
    Pfami PF02685. Glucokinase. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00749. glk. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The complete genome sequence of a chronic atrophic gastritis Helicobacter pylori strain: evolution during disease progression."
      Oh J.D., Kling-Baeckhed H., Giannakis M., Xu J., Fulton R.S., Fulton L.A., Cordum H.S., Wang C., Elliott G., Edwards J., Mardis E.R., Engstrand L.G., Gordon J.I.
      Proc. Natl. Acad. Sci. U.S.A. 103:9999-10004(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: HPAG1.

    Entry informationi

    Entry nameiGLK_HELPH
    AccessioniPrimary (citable) accession number: Q1CSG4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 12, 2006
    Last sequence update: July 11, 2006
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3