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Q1CS88 (DEOD_HELPH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Purine nucleoside phosphorylase DeoD-type

Short name=PNP
EC=2.4.2.1
Gene names
Name:deoD
Ordered Locus Names:HPAG1_1117
OrganismHelicobacter pylori (strain HPAG1) [Complete proteome] [HAMAP]
Taxonomic identifier357544 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length233 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Subunit structure

Homohexamer By similarity. HAMAP-Rule MF_01627

Sequence similarities

Belongs to the PNP/UDP phosphorylase family.

Ontologies

Keywords
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpurine nucleoside metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionpurine-nucleoside phosphorylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 233233Purine nucleoside phosphorylase DeoD-type HAMAP-Rule MF_01627
PRO_1000069635

Sequences

Sequence LengthMass (Da)Tools
Q1CS88 [UniParc].

Last modified July 11, 2006. Version 1.
Checksum: 8712253353DBE765

FASTA23325,761
        10         20         30         40         50         60 
MTPHINAKIG DFYPQCLLCG DPLRVSYIAK KFLQDAKEIT NVRNMLGFSG KYKGKGISLM 

        70         80         90        100        110        120 
GHGMGIASCT IYVTELIKTY QVKELLRIGT CGAISPKVGL KDIIMAMGAS TDSKTNRVRF 

       130        140        150        160        170        180 
LNHDLSATPD FELSLRAYQT AKRLGIDLKV GNVFSSDFFY SFETHAFDLM AQYNHLAIEM 

       190        200        210        220        230 
EAAGLYATAM ELSAKALCLC SVSDHLITKE ALSPKERVES FDNMIILALE MMS 

« Hide

References

[1]"The complete genome sequence of a chronic atrophic gastritis Helicobacter pylori strain: evolution during disease progression."
Oh J.D., Kling-Baeckhed H., Giannakis M., Xu J., Fulton R.S., Fulton L.A., Cordum H.S., Wang C., Elliott G., Edwards J., Mardis E.R., Engstrand L.G., Gordon J.I.
Proc. Natl. Acad. Sci. U.S.A. 103:9999-10004(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HPAG1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000241 Genomic DNA. Translation: ABF85184.1.
RefSeqYP_627858.1. NC_008086.1.

3D structure databases

ProteinModelPortalQ1CS88.
SMRQ1CS88. Positions 1-231.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING357544.HPAG1_1117.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABF85184; ABF85184; HPAG1_1117.
GeneID4098262.
KEGGhpa:HPAG1_1117.
PATRIC20603659. VBIHelPyl56048_1160.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0813.
HOGENOMHOG000274896.
KOK03784.
OMASFETHAF.
OrthoDBEOG6BKJC5.
ProtClustDBCLSK496399.

Enzyme and pathway databases

BioCycHPYL357544:GH1F-1144-MONOMER.

Family and domain databases

Gene3D3.40.50.1580. 1 hit.
HAMAPMF_01627. Pur_nucleosid_phosp.
InterProIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERPTHR21234. PTHR21234. 1 hit.
PfamPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMSSF53167. SSF53167. 1 hit.
TIGRFAMsTIGR00107. deoD. 1 hit.
PROSITEPS01232. PNP_UDP_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDEOD_HELPH
AccessionPrimary (citable) accession number: Q1CS88
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 11, 2006
Last modified: April 16, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families