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Q1CNS4

- G6PI_YERPN

UniProt

Q1CNS4 - G6PI_YERPN

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Protein
Glucose-6-phosphate isomerase
Gene
pgi, YPN_0023, YP516_4559
Organism
Yersinia pestis bv. Antiqua (strain Nepal516)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei355 – 3551Proton donor By similarity
Active sitei386 – 3861 By similarity
Active sitei514 – 5141 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciYPES377628:GIXK-29-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:YPN_0023
ORF Names:YP516_4559
OrganismiYersinia pestis bv. Antiqua (strain Nepal516)
Taxonomic identifieri377628 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000008936: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 548548Glucose-6-phosphate isomeraseUniRule annotation
PRO_1000014033Add
BLAST

Proteomic databases

PRIDEiQ1CNS4.

Interactioni

Protein-protein interaction databases

STRINGi377628.YPN_0023.

Structurei

3D structure databases

ProteinModelPortaliQ1CNS4.
SMRiQ1CNS4. Positions 7-548.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiNCHFVAN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1CNS4-1 [UniParc]FASTAAdd to Basket

« Hide

MKNINPSQTA AWKALQQHFE QMKDVTISSL FAKDDQRFNR FSATFDDQML    50
VDFSKNRITS ETLEKLQDLA KETDLAGAIK SMFSGEKINR TEDRAVLHIA 100
LRNRSNTPIV VDGKDVMPEV NAVLAKMKQF CDRVISGDWK GYTGKAITDV 150
VNIGIGGSDL GPYMVTEALR PYKNHLNMHF VSNVDGTHIA EALKPLNPET 200
TLFLVASKTF TTQETMTNAH SARDWFLSAA GDPAHVAKHF AALSTNAKAV 250
GEFGIDTNNM FEFWDWVGGR YSLWSAIGLS IALSVGFEHF EQLLSGAHAM 300
DKHFAETPAE KNLPVLLALI GIWYNNFFGA ETEAILPYDQ YMHRFPAYFQ 350
QGNMESNGKY VDRNGHPVDY QTGPIIWGEP GTNGQHAFYQ LIHQGTKLIP 400
CDFIAPAISH NPLSDHHAKL LSNFFAQTEA LAFGKSLEDV EAEFAAAGKT 450
PEQVAHVAPF KVFEGNRPTN SILLREITPF SLGALIALYE HKIFTQGVIL 500
NIYTFDQWGV ELGKQLANRI LPELADDQEV TSHDSSTNAL INRFKNWR 548
Length:548
Mass (Da):61,161
Last modified:July 11, 2006 - v1
Checksum:i3ED9D49B3A308A3B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000305 Genomic DNA. Translation: ABG16356.1.
ACNQ01000019 Genomic DNA. Translation: EEO74942.1.
RefSeqiYP_645956.1. NC_008149.1.

Genome annotation databases

EnsemblBacteriaiABG16356; ABG16356; YPN_0023.
EEO74942; EEO74942; YP516_4559.
GeneIDi4124258.
KEGGiypn:YPN_0023.
PATRICi18598910. VBIYerPes46733_0164.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000305 Genomic DNA. Translation: ABG16356.1 .
ACNQ01000019 Genomic DNA. Translation: EEO74942.1 .
RefSeqi YP_645956.1. NC_008149.1.

3D structure databases

ProteinModelPortali Q1CNS4.
SMRi Q1CNS4. Positions 7-548.
ModBasei Search...

Protein-protein interaction databases

STRINGi 377628.YPN_0023.

Proteomic databases

PRIDEi Q1CNS4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG16356 ; ABG16356 ; YPN_0023 .
EEO74942 ; EEO74942 ; YP516_4559 .
GeneIDi 4124258.
KEGGi ypn:YPN_0023.
PATRICi 18598910. VBIYerPes46733_0164.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi NCHFVAN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci YPES377628:GIXK-29-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516: evidence of gene reduction in an emerging pathogen."
    Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M., Worsham P., Chu M.C., Andersen G.L.
    J. Bacteriol. 188:4453-4463(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nepal516.
  2. "Yersinia pestis Nepal516A whole genome shotgun sequencing project."
    Plunkett G. III, Anderson B.D., Baumler D.J., Burland V., Cabot E.L., Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C., Tapia R., Green L.D., Rogers Y.C., Detter J.C., Bruce D.C., Brettin T.S.
    Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiG6PI_YERPN
AccessioniPrimary (citable) accession number: Q1CNS4
Secondary accession number(s): D1Q339
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 11, 2006
Last modified: June 11, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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