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Q1CN91

- Q1CN91_YERPN

UniProt

Q1CN91 - Q1CN91_YERPN

Protein
Submitted name:

Bifunctional biotin-[acetylCoA carboxylase] holoenzyme synthetase/DNA-binding transcriptional repressor, bio-5'-AMP-binding

Gene

birA

Organism
Yersinia pestis bv. Antiqua (strain Nepal516)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (11 Jul 2006)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. biotin-[acetyl-CoA-carboxylase] ligase activity Source: UniProtKB-EC
    2. DNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. cellular protein modification process Source: InterPro
    2. regulation of transcription, DNA-templated Source: InterPro

    Keywords - Molecular functioni

    LigaseImported

    Keywords - Ligandi

    DNA-bindingImported

    Enzyme and pathway databases

    BioCyciYPES377628:GIXK-228-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Bifunctional biotin-[acetylCoA carboxylase] holoenzyme synthetase/DNA-binding transcriptional repressor, bio-5'-AMP-bindingImported (EC:6.3.4.15Imported)
    Submitted name:
    Bifunctional protein BirAImported (EC:6.3.4.15Imported)
    Gene namesi
    Name:birAImported
    Ordered Locus Names:YPN_0206Imported
    ORF Names:YP516_0181Imported
    OrganismiYersinia pestis bv. Antiqua (strain Nepal516)Imported
    Taxonomic identifieri377628 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000008936: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi377628.YPN_0206.

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG0340.
    HOGENOMiHOG000041812.
    KOiK03524.
    OMAiADVCHVV.
    OrthoDBiEOG6DNTBX.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    InterProiIPR004408. Biotin_CoA_COase_ligase.
    IPR004409. Biotin_operon_repress_HTH.
    IPR003142. BPL_C.
    IPR004143. BPL_LipA_LipB.
    IPR013196. HTH_11.
    IPR008988. Transcriptional_repressor_C.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PANTHERiPTHR12835. PTHR12835. 1 hit.
    PfamiPF02237. BPL_C. 1 hit.
    PF03099. BPL_LplA_LipB. 1 hit.
    PF08279. HTH_11. 1 hit.
    [Graphical view]
    SUPFAMiSSF50037. SSF50037. 1 hit.
    TIGRFAMsiTIGR00121. birA_ligase. 1 hit.
    TIGR00122. birA_repr_reg. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q1CN91-1 [UniParc]FASTAAdd to Basket

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    MKDIRVPLRL VSILSDGFFH SGEQLGETLG MSRAAINKHM QTIRDWGLDV    50
    FTVPGKGYSL PTSIQLLDEQ KILSYLPTGH VTVLPVVDST NQYLLDRITE 100
    LKSGDACVAE YQQAGRGRRG RQWVSPFGAN LYLSMYWRLE QGPAAAMGLS 150
    LVVGIVMAEV LQNLGAEKVR VKWPNDLYLN DKKLAGILVE LTGKTGDAAQ 200
    LVIGAGINLT MRGSETNAIN QDWINLQDAG VTIDRNKLTA EILSELRLAV 250
    VKFENEGLSA FLSRWQKMDN YLNRPVKLII GNQEIFGIAR GIDQQGALLL 300
    EQDGNIKPYI GGEISLRGV 319
    Length:319
    Mass (Da):35,165
    Last modified:July 11, 2006 - v1
    Checksum:iB58E9306939E3B2A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000305 Genomic DNA. Translation: ABG16539.1.
    ACNQ01000003 Genomic DNA. Translation: EEO78492.1.
    RefSeqiYP_646139.1. NC_008149.1.

    Genome annotation databases

    EnsemblBacteriaiABG16539; ABG16539; YPN_0206.
    EEO78492; EEO78492; YP516_0181.
    GeneIDi4126530.
    KEGGiypn:YPN_0206.
    PATRICi18599349. VBIYerPes46733_0368.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000305 Genomic DNA. Translation: ABG16539.1 .
    ACNQ01000003 Genomic DNA. Translation: EEO78492.1 .
    RefSeqi YP_646139.1. NC_008149.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 377628.YPN_0206.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABG16539 ; ABG16539 ; YPN_0206 .
    EEO78492 ; EEO78492 ; YP516_0181 .
    GeneIDi 4126530.
    KEGGi ypn:YPN_0206.
    PATRICi 18599349. VBIYerPes46733_0368.

    Phylogenomic databases

    eggNOGi COG0340.
    HOGENOMi HOG000041812.
    KOi K03524.
    OMAi ADVCHVV.
    OrthoDBi EOG6DNTBX.

    Enzyme and pathway databases

    BioCyci YPES377628:GIXK-228-MONOMER.

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    InterProi IPR004408. Biotin_CoA_COase_ligase.
    IPR004409. Biotin_operon_repress_HTH.
    IPR003142. BPL_C.
    IPR004143. BPL_LipA_LipB.
    IPR013196. HTH_11.
    IPR008988. Transcriptional_repressor_C.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    PANTHERi PTHR12835. PTHR12835. 1 hit.
    Pfami PF02237. BPL_C. 1 hit.
    PF03099. BPL_LplA_LipB. 1 hit.
    PF08279. HTH_11. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50037. SSF50037. 1 hit.
    TIGRFAMsi TIGR00121. birA_ligase. 1 hit.
    TIGR00122. birA_repr_reg. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516: evidence of gene reduction in an emerging pathogen."
      Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M., Worsham P., Chu M.C., Andersen G.L.
      J. Bacteriol. 188:4453-4463(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Nepal516Imported.
    2. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Nepal516Imported.
    3. "Yersinia pestis Nepal516A whole genome shotgun sequencing project."
      Plunkett G.III., Anderson B.D., Baumler D.J., Burland V., Cabot E.L., Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C., Tapia R., Green L.D., Rogers Y.C., Detter J.C., Bruce D.C., Brettin T.S.
      Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Nepal516Imported.

    Entry informationi

    Entry nameiQ1CN91_YERPN
    AccessioniPrimary (citable) accession number: Q1CN91
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 11, 2006
    Last sequence update: July 11, 2006
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3