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Q1CN91

- Q1CN91_YERPN

UniProt

Q1CN91 - Q1CN91_YERPN

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Protein
Submitted name:

Bifunctional biotin-[acetylCoA carboxylase] holoenzyme synthetase/DNA-binding transcriptional repressor, bio-5'-AMP-binding

Gene
birA, YPN_0206, YP516_0181
Organism
Yersinia pestis bv. Antiqua (strain Nepal516)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. biotin-[acetyl-CoA-carboxylase] ligase activity Source: UniProtKB-EC
  2. DNA binding Source: UniProtKB-KW

GO - Biological processi

  1. cellular protein modification process Source: InterPro
  2. regulation of transcription, DNA-templated Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Keywords - Ligandi

DNA-bindingImported

Enzyme and pathway databases

BioCyciYPES377628:GIXK-228-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Bifunctional biotin-[acetylCoA carboxylase] holoenzyme synthetase/DNA-binding transcriptional repressor, bio-5'-AMP-bindingImported (EC:6.3.4.15Imported)
Submitted name:
Bifunctional protein BirAImported (EC:6.3.4.15Imported)
Gene namesi
Name:birAImported
Ordered Locus Names:YPN_0206Imported
ORF Names:YP516_0181Imported
OrganismiYersinia pestis bv. Antiqua (strain Nepal516)Imported
Taxonomic identifieri377628 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000008936: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi377628.YPN_0206.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0340.
HOGENOMiHOG000041812.
KOiK03524.
OMAiADVCHVV.
OrthoDBiEOG6DNTBX.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR004408. Biotin_CoA_COase_ligase.
IPR004409. Biotin_operon_repress_HTH.
IPR003142. BPL_C.
IPR004143. BPL_LipA_LipB.
IPR013196. HTH_11.
IPR008988. Transcriptional_repressor_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERiPTHR12835. PTHR12835. 1 hit.
PfamiPF02237. BPL_C. 1 hit.
PF03099. BPL_LplA_LipB. 1 hit.
PF08279. HTH_11. 1 hit.
[Graphical view]
SUPFAMiSSF50037. SSF50037. 1 hit.
TIGRFAMsiTIGR00121. birA_ligase. 1 hit.
TIGR00122. birA_repr_reg. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1CN91-1 [UniParc]FASTAAdd to Basket

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MKDIRVPLRL VSILSDGFFH SGEQLGETLG MSRAAINKHM QTIRDWGLDV    50
FTVPGKGYSL PTSIQLLDEQ KILSYLPTGH VTVLPVVDST NQYLLDRITE 100
LKSGDACVAE YQQAGRGRRG RQWVSPFGAN LYLSMYWRLE QGPAAAMGLS 150
LVVGIVMAEV LQNLGAEKVR VKWPNDLYLN DKKLAGILVE LTGKTGDAAQ 200
LVIGAGINLT MRGSETNAIN QDWINLQDAG VTIDRNKLTA EILSELRLAV 250
VKFENEGLSA FLSRWQKMDN YLNRPVKLII GNQEIFGIAR GIDQQGALLL 300
EQDGNIKPYI GGEISLRGV 319
Length:319
Mass (Da):35,165
Last modified:July 11, 2006 - v1
Checksum:iB58E9306939E3B2A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000305 Genomic DNA. Translation: ABG16539.1.
ACNQ01000003 Genomic DNA. Translation: EEO78492.1.
RefSeqiYP_646139.1. NC_008149.1.

Genome annotation databases

EnsemblBacteriaiABG16539; ABG16539; YPN_0206.
EEO78492; EEO78492; YP516_0181.
GeneIDi4126530.
KEGGiypn:YPN_0206.
PATRICi18599349. VBIYerPes46733_0368.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000305 Genomic DNA. Translation: ABG16539.1 .
ACNQ01000003 Genomic DNA. Translation: EEO78492.1 .
RefSeqi YP_646139.1. NC_008149.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 377628.YPN_0206.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG16539 ; ABG16539 ; YPN_0206 .
EEO78492 ; EEO78492 ; YP516_0181 .
GeneIDi 4126530.
KEGGi ypn:YPN_0206.
PATRICi 18599349. VBIYerPes46733_0368.

Phylogenomic databases

eggNOGi COG0340.
HOGENOMi HOG000041812.
KOi K03524.
OMAi ADVCHVV.
OrthoDBi EOG6DNTBX.

Enzyme and pathway databases

BioCyci YPES377628:GIXK-228-MONOMER.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR004408. Biotin_CoA_COase_ligase.
IPR004409. Biotin_operon_repress_HTH.
IPR003142. BPL_C.
IPR004143. BPL_LipA_LipB.
IPR013196. HTH_11.
IPR008988. Transcriptional_repressor_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
PANTHERi PTHR12835. PTHR12835. 1 hit.
Pfami PF02237. BPL_C. 1 hit.
PF03099. BPL_LplA_LipB. 1 hit.
PF08279. HTH_11. 1 hit.
[Graphical view ]
SUPFAMi SSF50037. SSF50037. 1 hit.
TIGRFAMsi TIGR00121. birA_ligase. 1 hit.
TIGR00122. birA_repr_reg. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516: evidence of gene reduction in an emerging pathogen."
    Chain P.S., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M., Worsham P., Chu M.C., Andersen G.L.
    J. Bacteriol. 188:4453-4463(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nepal516Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Nepal516Imported.
  3. "Yersinia pestis Nepal516A whole genome shotgun sequencing project."
    Plunkett G. III, Anderson B.D., Baumler D.J., Burland V., Cabot E.L., Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C., Tapia R., Green L.D., Rogers Y.C., Detter J.C., Bruce D.C., Brettin T.S.
    Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nepal516.
  4. "Yersinia pestis Nepal516A whole genome shotgun sequencing project."
    Plunkett G.III., Anderson B.D., Baumler D.J., Burland V., Cabot E.L., Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C., Tapia R., Green L.D., Rogers Y.C., Detter J.C., Bruce D.C., Brettin T.S.
    Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nepal516Imported.

Entry informationi

Entry nameiQ1CN91_YERPN
AccessioniPrimary (citable) accession number: Q1CN91
Entry historyi
Integrated into UniProtKB/TrEMBL: July 11, 2006
Last sequence update: July 11, 2006
Last modified: July 9, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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