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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Yersinia pestis bv. Antiqua (strain Nepal516)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciYPES377628:GIXK-396-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:YPN_0364
ORF Names:YP516_0372
OrganismiYersinia pestis bv. Antiqua (strain Nepal516)
Taxonomic identifieri377628 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
Proteomesi
  • UP000008936 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 289289Bis(5'-nucleosyl)-tetraphosphatase, symmetricalPRO_1000012110Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ1CMT4.
SMRiQ1CMT4. Positions 2-266.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000251871.
KOiK01525.
OMAiINAFTRM.

Family and domain databases

Gene3Di3.60.21.10. 2 hits.
HAMAPiMF_00199. ApaH. 1 hit.
InterProiIPR004617. ApaH.
IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFiPIRSF000903. B5n-ttraPtase_sm. 1 hit.
SUPFAMiSSF56300. SSF56300. 1 hit.
TIGRFAMsiTIGR00668. apaH. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1CMT4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTYLIGDIH GCLDELLALL AQVNFDPQQD TLWLTGDLVA RGPASLDVLR
60 70 80 90 100
YVRSLGPAVR MVLGNHDLHL LAVYAGISRN KPKDRITPLL DAPDADELIN
110 120 130 140 150
WLRRQPVLQV DDQLKLIMAH AGITPQWDIE TAKMCAREVE AVLSSDSYPL
160 170 180 190 200
FLDAMYGDMP NNWSPELTGL ARLRFSTNAL TRMRFCFPNG QLDMICKDTP
210 220 230 240 250
ENAPAPLKPW FDLPRLVDPE YSIIFGHWAS LEGKGVPEGI YGLDTGCCWG
260 270 280
GDLTLLRWDD KRYFTQRAFK AEAEINNNNG FAAGEAVQH
Length:289
Mass (Da):32,341
Last modified:July 11, 2006 - v1
Checksum:i6E761EBC8A6A4A4A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000305 Genomic DNA. Translation: ABG16696.1.
ACNQ01000006 Genomic DNA. Translation: EEO78148.1.
RefSeqiWP_002210492.1. NZ_ACNQ01000006.1.

Genome annotation databases

EnsemblBacteriaiABG16696; ABG16696; YPN_0364.
EEO78148; EEO78148; YP516_0372.
KEGGiypn:YPN_0364.
PATRICi18599719. VBIYerPes46733_0544.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000305 Genomic DNA. Translation: ABG16696.1.
ACNQ01000006 Genomic DNA. Translation: EEO78148.1.
RefSeqiWP_002210492.1. NZ_ACNQ01000006.1.

3D structure databases

ProteinModelPortaliQ1CMT4.
SMRiQ1CMT4. Positions 2-266.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG16696; ABG16696; YPN_0364.
EEO78148; EEO78148; YP516_0372.
KEGGiypn:YPN_0364.
PATRICi18599719. VBIYerPes46733_0544.

Phylogenomic databases

HOGENOMiHOG000251871.
KOiK01525.
OMAiINAFTRM.

Enzyme and pathway databases

BioCyciYPES377628:GIXK-396-MONOMER.

Family and domain databases

Gene3Di3.60.21.10. 2 hits.
HAMAPiMF_00199. ApaH. 1 hit.
InterProiIPR004617. ApaH.
IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFiPIRSF000903. B5n-ttraPtase_sm. 1 hit.
SUPFAMiSSF56300. SSF56300. 1 hit.
TIGRFAMsiTIGR00668. apaH. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiAPAH_YERPN
AccessioniPrimary (citable) accession number: Q1CMT4
Secondary accession number(s): C4GNR6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 11, 2006
Last modified: September 7, 2016
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.