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Protein

Glutamate-ammonia-ligase adenylyltransferase

Gene

glnE

Organism
Yersinia pestis bv. Antiqua (strain Nepal516)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Adenylation and deadenylation of glutamate--ammonia ligase.UniRule annotation

Catalytic activityi

ATP + [glutamine synthetase]-L-tyrosine = diphosphate + [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

ATP-binding, Magnesium, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate-ammonia-ligase adenylyltransferaseUniRule annotation (EC:2.7.7.42UniRule annotation)
Alternative name(s):
Glutamine-synthetase adenylyltransferase
Short name:
ATaseUniRule annotation
[Glutamate--ammonia-ligase] adenylyltransferaseUniRule annotation
Gene namesi
Name:glnEUniRule annotation
Ordered Locus Names:YPN_0513
ORF Names:YP516_0533
OrganismiYersinia pestis bv. Antiqua (strain Nepal516)
Taxonomic identifieri377628 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000008936 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000470221 – 951Glutamate-ammonia-ligase adenylyltransferaseAdd BLAST951

Structurei

3D structure databases

ProteinModelPortaliQ1CMD5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni91 – 302GlnE 1Add BLAST212
Regioni609 – 830GlnE 2Add BLAST222

Sequence similaritiesi

Belongs to the GlnE family.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

HOGENOMiHOG000256491.
KOiK00982.
OMAiEFMVQYA.

Family and domain databases

HAMAPiMF_00802. GlnE. 1 hit.
InterProiIPR023057. GlnE.
IPR005190. GlnE_rpt_dom.
IPR013546. PII_UdlTrfase/GS_AdlTrfase.
[Graphical view]
PfamiPF08335. GlnD_UR_UTase. 2 hits.
PF03710. GlnE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1CMD5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPLPSELQI QAQSIKQRFS ELPAPPDLRD EDIAVLALSD FVSDMLLIHP
60 70 80 90 100
QWLEELHQQP PQPQEWQYYS QWLSQALAGV QDEAALLTAL RLFRRRVMVR
110 120 130 140 150
IAWSQVLQTS GTAETLQQLS TLAESMIIAA RDWLYQVCCR ELGTPCNRQG
160 170 180 190 200
VPQPLLILGM GKLGGGELNF SSDIDLIFAY PENGQTQGGR RELDNAQFFT
210 220 230 240 250
RLGQRLIKAL DQHTIDGFVY RVDMRLRPFG DSGPLVLSFA ALEDYYQEQG
260 270 280 290 300
RDWERYAMVK ARLMGGADDP YSQELRQMLR PFVFRRYIDF SVIQSLRNMK
310 320 330 340 350
GMIAREVRRR GLKDNIKLGA GGIREIEFIT QVFQLIRGGR EPRLQERALL
360 370 380 390 400
PTLQAVAELG LLPEQQVADL SGSYLFLRRL ENLLQAIADE QTQTLPNDPL
410 420 430 440 450
NQARLAWGMG YADWAAMSTA LENHMQAVRV VFDDLIGDET PDIGEDPSHG
460 470 480 490 500
LYKSLWQDVL EESDLAPLTP HLEEAARRQL LATISGFRHD VDKRTIGPRG
510 520 530 540 550
REVLDQLMPR LFAEVCPRPD ANVALSRLIL LLLSIVTRTT YLELLVEYHA
560 570 580 590 600
ALKHVIRLCS ASPMVASQLA RYPLLLDELL DPQSLYQPLA PSAYRDELRQ
610 620 630 640 650
YLLRVPEDDE EQQLEALRQF KQAQQLRIAA GDITEALPVM KVSDHLTYLA
660 670 680 690 700
EAIIDAVIQQ AWNQMVARYG QPSHLQQSEG RGFAVIGYGK LGGWELGYSS
710 720 730 740 750
DLDLVFLLDC PLDVMTDGDR SIDGRQFYLR LAQRIMHLFS TRTSSGILYE
760 770 780 790 800
VDARLRPSGE AGMLVSTIEA FADYQRNEAW TWEHQALVRA RIVYGSPKLH
810 820 830 840 850
QQFDAIRQQI LCRHREDPQL QQEVREMREK MRNHLGSKQR DIFDIKADAG
860 870 880 890 900
GITDIEFIAQ YLVLRYAASE PRLTRWSDNV RIFESMAHYD IMSPEEAAAL
910 920 930 940 950
TRAYVTMRDE IHHLALQEQS SKVAADSFIA EREQVAASWH KWLAANDANV

S
Length:951
Mass (Da):108,330
Last modified:July 11, 2006 - v1
Checksum:iB9FFEF8FC128B97E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000305 Genomic DNA. Translation: ABG16845.1.
ACNQ01000006 Genomic DNA. Translation: EEO78303.1.
RefSeqiWP_002212194.1. NZ_ACNQ01000006.1.

Genome annotation databases

EnsemblBacteriaiABG16845; ABG16845; YPN_0513.
EEO78303; EEO78303; YP516_0533.
KEGGiypn:YPN_0513.
PATRICi18600055. VBIYerPes46733_0712.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000305 Genomic DNA. Translation: ABG16845.1.
ACNQ01000006 Genomic DNA. Translation: EEO78303.1.
RefSeqiWP_002212194.1. NZ_ACNQ01000006.1.

3D structure databases

ProteinModelPortaliQ1CMD5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG16845; ABG16845; YPN_0513.
EEO78303; EEO78303; YP516_0533.
KEGGiypn:YPN_0513.
PATRICi18600055. VBIYerPes46733_0712.

Phylogenomic databases

HOGENOMiHOG000256491.
KOiK00982.
OMAiEFMVQYA.

Family and domain databases

HAMAPiMF_00802. GlnE. 1 hit.
InterProiIPR023057. GlnE.
IPR005190. GlnE_rpt_dom.
IPR013546. PII_UdlTrfase/GS_AdlTrfase.
[Graphical view]
PfamiPF08335. GlnD_UR_UTase. 2 hits.
PF03710. GlnE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLNE_YERPN
AccessioniPrimary (citable) accession number: Q1CMD5
Secondary accession number(s): C4GP71
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 11, 2006
Last modified: November 2, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.