true2008-01-152024-03-2798LIPA_YERPNComplete genome sequence of Yersinia pestis strains Antiqua and Nepal516: evidence of gene reduction in an emerging pathogen.Chain P.S.G.Hu P.Malfatti S.A.Radnedge L.Larimer F.Vergez L.M.Worsham P.Chu M.C.Andersen G.L.doi:10.1128/jb.00124-062006J. Bacteriol.1884453-4463NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]Nepal516Yersinia pestis Nepal516A whole genome shotgun sequencing project.Plunkett G. IIIAnderson B.D.Baumler D.J.Burland V.Cabot E.L.Glasner J.D.Mau B.Neeno-Eckwall E.Perna N.T.Munk A.C.Tapia R.Green L.D.Rogers Y.C.Detter J.C.Bruce D.C.Brettin T.S.2009-04EMBL/GenBank/DDBJNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]Radical_SAMAldolase class ILipoyl_synthAldolase_TIMElp3/MiaA/NifB-like_rSAMLIAS_NLipoyl_synthrSAMlipALIPOYL SYNTHASELIPOYL SYNTHASE, MITOCHONDRIALLIAS_NRadical_SAMLipoyl_synthlipoyl_synthaselipoyl_synthase_likeElp3Radical SAM enzymesRADICAL_SAMLipoyl synthase2.8.1.8Lip-synLSLipoate synthaseLipoic acid synthaseSulfur insertion protein LipAlipAYPN_1083YP516_1177Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.Belongs to the radical SAM superfamily. Lipoyl synthase family.Lipoyl synthase360861321Radical SAM core802976873799498101308124Fe-4S-S-AdoMet2006-07-11136086c11b031c550889f9fc70034d0cd85dd5MSKPIQMERGVKYRDADKMALIPVKNVVTERQELLRKPEWLKIKLPTDSSRIQGIKAAMRKNGLHSVCEEASCPNLSECFNHGTATFMILGAICTRRCPFCDVAHGRPVTPDANEPEKLAQTIQDMGLRYVVITSVDRDDLRDGGAQHFADCISAIRAKNPTIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRVYRQVRPGANYDWSLKLLERFKEAHPDIPTKSGLMVGLGETNAEIVEVMHDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPAEFDEMKAEAMAMGFTHAACGPFVRSSYHADLQAKGMEVKtruetrue