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Q1CJU5

- GLK_YERPN

UniProt

Q1CJU5 - GLK_YERPN

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Protein

Glucokinase

Gene

glk

Organism
Yersinia pestis bv. Antiqua (strain Nepal516)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi8 – 136ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glucokinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYPES377628:GIXK-1463-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlucokinaseUniRule annotation (EC:2.7.1.2UniRule annotation)
Alternative name(s):
Glucose kinaseUniRule annotation
Gene namesi
Name:glkUniRule annotation
Ordered Locus Names:YPN_1405
ORF Names:YP516_1560
OrganismiYersinia pestis bv. Antiqua (strain Nepal516)
Taxonomic identifieri377628 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000008936: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 323323GlucokinasePRO_0000268795Add
BLAST

Proteomic databases

PRIDEiQ1CJU5.

Interactioni

Protein-protein interaction databases

STRINGi377628.YPN_1405.

Structurei

3D structure databases

ProteinModelPortaliQ1CJU5.
SMRiQ1CJU5. Positions 2-321.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial glucokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiDWVEMTN.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

Q1CJU5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTTYALVGDV GGTNARLALC AVATGEILQA KTYSGLEYES LEDVIKQYLS
60 70 80 90 100
EHQAKVTDAC IAIACPITGD WVAMTNHTWA FSIAAMQQNL GLDHLEVIND
110 120 130 140 150
FTAVSMAIPV LPAQDVLQFG GTQPQPGKPV AVYGAGTGLG VAHLVNVDRR
160 170 180 190 200
WISLAGEGGH VDFAPNSEEE DQILAVLRQE LGHVSAERVL SGPGLVNLYR
210 220 230 240 250
AIVISDARLP EKLAPKDITA RALADSCTDC RRALSLFCVI MGRFGGNLAL
260 270 280 290 300
NLSTFGGVYI AGGIVPRFME FFKASGFRAA FEDKGRFKDF LQDIPVYMIT
310 320
HPQPGLLGAG AYLRQKLGYE LSS
Length:323
Mass (Da):34,664
Last modified:July 11, 2006 - v1
Checksum:iA2465D600781CE37
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000305 Genomic DNA. Translation: ABG17735.1.
ACNQ01000009 Genomic DNA. Translation: EEO76833.1.
RefSeqiYP_647335.1. NC_008149.1.

Genome annotation databases

EnsemblBacteriaiABG17735; ABG17735; YPN_1405.
EEO76833; EEO76833; YP516_1560.
GeneIDi4123645.
KEGGiypn:YPN_1405.
PATRICi18602155. VBIYerPes46733_1738.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000305 Genomic DNA. Translation: ABG17735.1 .
ACNQ01000009 Genomic DNA. Translation: EEO76833.1 .
RefSeqi YP_647335.1. NC_008149.1.

3D structure databases

ProteinModelPortali Q1CJU5.
SMRi Q1CJU5. Positions 2-321.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 377628.YPN_1405.

Proteomic databases

PRIDEi Q1CJU5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG17735 ; ABG17735 ; YPN_1405 .
EEO76833 ; EEO76833 ; YP516_1560 .
GeneIDi 4123645.
KEGGi ypn:YPN_1405.
PATRICi 18602155. VBIYerPes46733_1738.

Phylogenomic databases

eggNOGi COG0837.
HOGENOMi HOG000274469.
KOi K00845.
OMAi DWVEMTN.
OrthoDBi EOG64BQ47.

Enzyme and pathway databases

BioCyci YPES377628:GIXK-1463-MONOMER.

Family and domain databases

HAMAPi MF_00524. Glucokinase.
InterProi IPR003836. Glucokinase.
[Graphical view ]
Pfami PF02685. Glucokinase. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00749. glk. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516: evidence of gene reduction in an emerging pathogen."
    Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M., Worsham P., Chu M.C., Andersen G.L.
    J. Bacteriol. 188:4453-4463(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nepal516.
  2. "Yersinia pestis Nepal516A whole genome shotgun sequencing project."
    Plunkett G. III, Anderson B.D., Baumler D.J., Burland V., Cabot E.L., Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C., Tapia R., Green L.D., Rogers Y.C., Detter J.C., Bruce D.C., Brettin T.S.
    Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiGLK_YERPN
AccessioniPrimary (citable) accession number: Q1CJU5
Secondary accession number(s): C4GS23
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: July 11, 2006
Last modified: October 29, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3