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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Yersinia pestis bv. Antiqua (strain Nepal516)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:YPN_1523
ORF Names:YP516_1690
OrganismiYersinia pestis bv. Antiqua (strain Nepal516)
Taxonomic identifieri377628 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000008936 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000181471 – 576Arginine--tRNA ligaseAdd BLAST576

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ1CJH7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi122 – 132"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247212.
KOiK01887.
OMAiKLVGNYY.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q1CJH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIQALLSDK VSQALIAAGA PADCEAQVRQ SAKAQFGDYQ ANGVMAVAKK
60 70 80 90 100
LGMQPRQLAE RVVELLDLTG IASKIEIAGP GFINIFLDRQ WVAEKVEYAL
110 120 130 140 150
TAPKLGVAPV EPQTIVVDYS APNVAKQMHV GHLRSTIIGD AAVRTLAFLG
160 170 180 190 200
HNVIRANHVG DWGTQFGMLI AYLEKMQNEN ASDMGLSDLE LFYQQAKKTY
210 220 230 240 250
DEDEEFSLRA RAYVVKLQSG DEYCRQMWRK LVDITMAQNQ VAYDRLNVTL
260 270 280 290 300
TKDDVMGESL YNAMLPEIVA DLKAKGLAVE SEGATVVYLD EYKNKDGEPM
310 320 330 340 350
GVIIQKKDGG YLYTTTDIAC AKYRYETLGA DRILYYIDSR QHQHLMQAWT
360 370 380 390 400
IVRKAGYVPE SVPLEHHMFG MMLGKDGKPF KTRSGGTVKL SDLLDEAVER
410 420 430 440 450
AGKLIAEKNP DMPADELKQV INAVGIGAVK YADLSKSRTT DYIFDWDNML
460 470 480 490 500
ALDGNTAPYM QYAYTRVVSV FRRAGVDETS LTLPLVVTED REATLATRLL
510 520 530 540 550
QFEEIITTVA REGTPHVMCS YLYDLAGLFS SFYEHCQILN AESEEIRQSR
560 570
LKLAMLTAKT LKQGLDTLGI QTVERM
Length:576
Mass (Da):64,158
Last modified:July 11, 2006 - v1
Checksum:iC63BF8030B059913
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000305 Genomic DNA. Translation: ABG17853.1.
ACNQ01000009 Genomic DNA. Translation: EEO76958.1.
RefSeqiWP_002228433.1. NZ_ACNQ01000009.1.

Genome annotation databases

EnsemblBacteriaiABG17853; ABG17853; YPN_1523.
EEO76958; EEO76958; YP516_1690.
KEGGiypn:YPN_1523.
PATRICi18602424. VBIYerPes46733_1872.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000305 Genomic DNA. Translation: ABG17853.1.
ACNQ01000009 Genomic DNA. Translation: EEO76958.1.
RefSeqiWP_002228433.1. NZ_ACNQ01000009.1.

3D structure databases

ProteinModelPortaliQ1CJH7.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG17853; ABG17853; YPN_1523.
EEO76958; EEO76958; YP516_1690.
KEGGiypn:YPN_1523.
PATRICi18602424. VBIYerPes46733_1872.

Phylogenomic databases

HOGENOMiHOG000247212.
KOiK01887.
OMAiKLVGNYY.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSYR_YERPN
AccessioniPrimary (citable) accession number: Q1CJH7
Secondary accession number(s): C4GSE8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 11, 2006
Last modified: November 2, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.