Reviewed, UniProtKB/Swiss-Prot Q1CIX8 (ARAB_YERPN)

Names and origin

Protein names

Recommended name:
    Ribulokinase
    EC=2.7.1.16

Gene names

Name:	araB
Ordered Locus Names:	YPN_1723
ORF Names:	YP516_1914

Organism

Yersinia pestis bv. Antiqua (strain Nepal516) [Complete proteome] [HAMAP]

Taxonomic identifier

377628 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia

Protein attributes

Sequence length	567 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate. HAMAP MF_00520
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 2/3. HAMAP MF_00520
Sequence similarities	Belongs to the ribulokinase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	L-arabinose catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ribulokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 567	567	Ribulokinase HAMAP MF_00520		PRO_0000263411

Sequences

	Sequence		Length	Mass (Da)
	Q1CIX8-1 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: A614A0434E334B5D	FASTA	567	62,205
	10 20 30 40 50 60 MTGNVISADG AIALGLDFGS DSVRVLAVDC QHGTEIDTEV VYYPRWKKGL YCQAAQNQFR 70 80 90 100 110 120 HHPLDYIEAM EQAIRQMVKR LSEEQRQHIV GIGVDSTGST PAPIDEQGQV LALRPDFADN 130 140 150 160 170 180 PNAMFVLWKD HTAIEEAEEI NRLCRSGEFA DYSRYIGGVY SSEWFWAKIL HVTRADVAVR 190 200 210 220 230 240 EAAVSWIELC DWVPALLSGT TAPQDIQRGR CSAGHKSLWH PSWGGLPPRA FLAALDTSLV 250 260 270 280 290 300 NDLDYPMFTD TYTAERPVGQ ITAEWAERLG LPTTVILSGG AFDCHMGAVG AGAQPYTLVK 310 320 330 340 350 360 VIGTSTCDIL IADDQRVGDR AIAGICGQVE GSVLPGWIGM EAGQSAFGDM YAWFSNLLSW 370 380 390 400 410 420 PLHQAALTQP EWQPQLKQIE SNLLASLTRA WAQNPSLDHL PVVLDWFNGR RTPNANQRLK 430 440 450 460 470 480 GVITDLNLGT DAPTLFGGFI AATAFGARAI MECFEQQDIP IDNVLALGGI ARKSPVIMQV 490 500 510 520 530 540 CADVMNRPLQ IVASDQCCAL GAAIFAAVAA GAHDDVPTAQ RHMACNIERT LIPDPVQVVR 550 560 YQQLYQRYQQ WCHTAEPHYA PVTKVIH

References

[1]	"Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516: evidence of gene reduction in an emerging pathogen." Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M., Worsham P., Chu M.C., Andersen G.L. J. Bacteriol. 188:4453-4463(2006) [PubMed: 16740952] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Yersinia pestis Nepal516A whole genome shotgun sequencing project." Plunkett G. III, Anderson B.D., Baumler D.J., Burland V., Cabot E.L., Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C., Tapia R., Green L.D., Rogers Y.C., Detter J.C., Bruce D.C., Brettin T.S. Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000305 Genomic DNA. Translation: ABG18052.1. ACNQ01000009 Genomic DNA. Translation: EEO77179.1.
RefSeq	YP_647652.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q1CIX8.
Genome annotation databases
GeneID	4123199.
GenomeReviews	Gene locus YPN_1723 in contig CP000305_GR.
KEGG	ypn:YPN_1723.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q1CIX8.
OMA	NGRRTPD.
Enzyme and pathway databases
BioCyc	YPES377628:YPN_1723-MON.
Family and domain databases
HAMAP	MF_00520. [Tree]
InterPro	IPR000577. Carb_kinase_FGGY. IPR018485. Carb_kinase_FGGY_C. IPR018484. Carb_kinase_FGGY_N. IPR005929. L_ribulokin. [Graphical view]
PANTHER	PTHR10196. FGGY_kin. 1 hit.
Pfam	PF02782. FGGY_C. 1 hit. PF00370. FGGY_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR01234. L-ribulokinase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARAB_YERPN

Accession

Primary (citable) accession number: Q1CIX8
Secondary accession number(s): C4GT19

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	July 11, 2006
Last modified:	November 3, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)