Q1CIA7 (Q1CIA7_YERPN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Ordered Locus Names:	YPN_1944 EMBL ABG18273.1
ORF Names:	YP516_2164 EMBL EEO76570.1

Organism

Yersinia pestis bv. Antiqua (strain Nepal516) [Complete proteome] [HAMAP] EMBL ABG18273.1

Taxonomic identifier

377628 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia › Yersinia pestis

Protein attributes

Sequence length	409 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Domain	Signal EMBL ABG18273.1
Ligand	Pyridoxal phosphate SAAS SAAS020622
Molecular function	Isomerase SAAS SAAS020622 EMBL ABG18273.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 26	26	Potential EMBL ABG18273.1
	Chain	27 – 409	383	Potential		PRO_5000115363

Sequences

	Sequence		Length	Mass (Da)
	Q1CIA7 [UniParc]. Last modified July 11, 2006. Version 1. Checksum: BBFCC8C5A2E4241C	FASTA	409	44,770
	10 20 30 40 50 60 MHVRFRHLFL LPLITLVACS QPVSKNHLSL TSLSANAQQP VVNNAWLEIS QGALDFNTKK 70 80 90 100 110 120 MLTLLDNKST LCAILKGDAY GHDLTLVTPV MLKNNVQCIG VASNQELKTV RDLGFTGQLI 130 140 150 160 170 180 RVRSATLKEM QQAMAYDVEE LIGDKTVAEQ LNNIAKLNGK VLRIHLALNS AGMSRNGLEV 190 200 210 220 230 240 SKARGLNDAK TIAGLKNLTI VGIMSHYPVE DASEIKADLA RFQQQAKDVI AVTGLKREKI 250 260 270 280 290 300 KLHVANTFAT LAVPDSWLDM VRVGGVFYGD TIASTEYKRV MTFKSNIASL NNYPKGGTVG 310 320 330 340 350 360 YDRTYTLKRD SLLANIPVGY ADGYRRVFSN AGHVIIQGQR LPVLGKTSMN TVIVDVTDLK 370 380 390 400 KVSLGDEVVL FGKQGNAEIQ AEEIEDLSGA LFTEMSILWG ATNKRILVD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516: evidence of gene reduction in an emerging pathogen." Chain P.S., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M., Worsham P., Chu M.C., Andersen G.L. J. Bacteriol. 188:4453-4463(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nepal516 EMBL ABG18273.1.
[2]	"Complete sequence of chromosome of Yersinia pestis Nepal516." US DOE Joint Genome Institute Barry K., Lucas S., Lapidus A., Copeland A., Detter J.C., Glavina del Rio T., Hammon N., Dalin E., Tice H., Pitluck S., Chain P., Hu P., Malfatti S.A., Radnedge L., Vergez L.M., Larimer F., Land M., Hauser L. , Worsham P., Chu M.C., Andersen G., Richardson P. Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Nepal516 EMBL ABG18273.1.
[3]	"Yersinia pestis Nepal516A whole genome shotgun sequencing project." Plunkett G.III., Anderson B.D., Baumler D.J., Burland V., Cabot E.L., Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C., Tapia R., Green L.D., Rogers Y.C., Detter J.C., Bruce D.C., Brettin T.S. Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nepal516 EMBL EEO76570.1.
[4]	"Yersinia pestis Nepal516A whole genome shotgun sequencing project." Plunkett G. III, Anderson B.D., Baumler D.J., Burland V., Cabot E.L., Glasner J.D., Mau B., Neeno-Eckwall E., Perna N.T., Munk A.C., Tapia R., Green L.D., Rogers Y.C., Detter J.C., Bruce D.C., Brettin T.S. Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nepal516.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000305 Genomic DNA. Translation: ABG18273.1. ACNQ01000011 Genomic DNA. Translation: EEO76570.1.
RefSeq	YP_647873.1. NC_008149.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	377628.YPN_1944.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABG18273; ABG18273; YPN_1944. EEO76570; EEO76570; YP516_2164.
GeneID	4122717.
KEGG	ypn:YPN_1944.
PATRIC	18603372. VBIYerPes46733_2346.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0787.
HOGENOM	HOG000279190.
KO	K01775.
OMA	NTVGYDR.
ProtClustDB	PRK13340.
Enzyme and pathway databases
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q1CIA7_YERPN

Accession

Primary (citable) accession number: Q1CIA7

Entry history

Integrated into UniProtKB/TrEMBL:	July 11, 2006
Last sequence update:	July 11, 2006
Last modified:	May 1, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)